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Recent Progress in the Development and Clinical Application of New Drugs for Transthyretin Cardiac Amyloidosis
Recent Progress in the Development and Clinical Application of New Drugs for Transthyretin Cardiac Amyloidosis
Abstract: Transthyretincardiac amyloidosis is a rare disease that has gained significant attentio
Knockout of Matrix Metalloproteinase 2 Opposes Hypertension- and Diabetes-induced Nephropathy
Knockout of Matrix Metalloproteinase 2 Opposes Hypertension- and Diabetes-induced Nephropathy
Abstract: The progression of chronic kidney disease results from the accumulation of extracellula
Transcription Factor TCF3 Promotes Macrophage-Mediated Inflammation and MMP Secretion in Abdominal Aortic Aneurysm by Regulating miR-143-5p/CCL20
Transcription Factor TCF3 Promotes Macrophage-Mediated Inflammation and MMP Secretion in Abdominal Aortic Aneurysm by Regulating miR-143-5p/CCL20
Abstract: Damage to the abdominal aortic wall and the local inflammatory response are key factors
Matrix Metalloproteinase 2 Is Crucial for Hypertension- and Hyperglycemia-Induced Kidney Injury Independent of Blood Pressure
Matrix Metalloproteinase 2 Is Crucial for Hypertension- and Hyperglycemia-Induced Kidney Injury Independent of Blood Pressure
In the United States, kidney diseases are a leading cause of death. According to the Center for Disease Control and Preven...
Molecular Insights on Ischemic Heart Failure: From Core Genes to Hearts
Molecular Insights on Ischemic Heart Failure: From Core Genes to Hearts
Because of this, originality consists in returning to the origin — Antoni Gaudi The in...
Anthracyclines and Cardiotoxicity: Is CARP a Forgotten Biomarker?
Anthracyclines and Cardiotoxicity: Is CARP a Forgotten Biomarker?
In this issue of the Journal of Cardiovascular Pharmacology, Li et al1 show that cardiac adriamycin-responsive protein (CA...
GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
Abstract: Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is
Post-Acute Myocardial Infarction Heart Failure Core Genes and Relevant Signaling Pathways
Post-Acute Myocardial Infarction Heart Failure Core Genes and Relevant Signaling Pathways
Abstract: There is increasing concern about heart failure after myocardial infarction and the cur
Influence of Regional Nerve Block in Addition to General Anesthesia on Postoperative Delirium, Pain, and In-hospital Stay in Patients Undergoing Cardiothoracic Surgery: A Meta-analysis
Influence of Regional Nerve Block in Addition to General Anesthesia on Postoperative Delirium, Pain, and In-hospital Stay in Patients Undergoing Cardiothoracic Surgery: A Meta-analysis
Abstract: This study aims to investigate whether venous injection of sedative agent or regional n
Potential Biomarker of Acute Anthracycline-induced Cardiotoxicity Among Children With Acute Lymphoblastic Leukemia: Cardiac Adriamycin-responsive Protein
Potential Biomarker of Acute Anthracycline-induced Cardiotoxicity Among Children With Acute Lymphoblastic Leukemia: Cardiac Adriamycin-responsive Protein
Abstract: This study aimed to investigate whether serum cardiac adriamycin-responsive protein (CA
Statins in Patients With Established Heart Failure: Time for Reflection
Statins in Patients With Established Heart Failure: Time for Reflection
The development and clinical application of statins has been one of the most significant advances in health care over the ...
The Potential Role of Visfatin in Mediating Vascular Dysfunction and Hypertension
The Potential Role of Visfatin in Mediating Vascular Dysfunction and Hypertension
Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) was first discovered as a cytokine named pre-B-cell colony-enhanci...
Association of the L3MBTL3 rs1125970 and rs4897367 Gene Polymorphisms With Coronary Heart Disease Susceptibility in the Chinese Population: A Case–Control Study
Association of the L3MBTL3 rs1125970 and rs4897367 Gene Polymorphisms With Coronary Heart Disease Susceptibility in the Chinese Population: A Case–Control Study
Abstract: Coronary heart disease (CHD) is a prevalent heart disease with high incidence and morta
MiR-590-3p Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells by Targeting Lysyl Oxidase
MiR-590-3p Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells by Targeting Lysyl Oxidase
Abstract: We investigated the clinical characteristics of patients with acute aortic dissection (
The STING-IRF3 Signaling Pathway, Mediated by Endoplasmic Reticulum Stress, Contributes to Impaired Myocardial Autophagic Flux After Ischemia/Reperfusion
The STING-IRF3 Signaling Pathway, Mediated by Endoplasmic Reticulum Stress, Contributes to Impaired Myocardial Autophagic Flux After Ischemia/Reperfusion
This study aimed to determine whether endoplasmic reticulum (ER) stress is involved in impaired auto
Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2–associated PINK/Parkin Pathway
Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2–associated PINK/Parkin Pathway
Chronic alcohol intake contributes to high mortality rates due to ethanol-induced cardiac hypertroph
Long-term Cardiovascular Adverse Events Induced by Fluoroquinolones: A Retrospective Case–control Study
Long-term Cardiovascular Adverse Events Induced by Fluoroquinolones: A Retrospective Case–control Study
Abstract: A correlation is already established between fluoroquinolones (FQs) use and cardiovascu
Clinical and Hemodynamic Improvement in Pulmonary Hypertension After Switching to Sacubitril/Valsartan in Patients With Heart Failure With Preserved Ejection Fraction
Clinical and Hemodynamic Improvement in Pulmonary Hypertension After Switching to Sacubitril/Valsartan in Patients With Heart Failure With Preserved Ejection Fraction
Abstract: Patients with heart failure with preserved ejection fraction (HFpEF) and pulmonary hype
Comparison of Ticagrelor Monotherapy and Ticagrelor Plus Aspirin Among Patients With Acute Coronary Syndrome Combined With High-Risk of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Retrospective Cohort Study
Comparison of Ticagrelor Monotherapy and Ticagrelor Plus Aspirin Among Patients With Acute Coronary Syndrome Combined With High-Risk of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Retrospective Cohort Study
Abstract: To date, no studies have specifically examined the efficacy of P2Y12 inhibitor monother
San Jie Tong Mai Fang Protects Against Atherosclerosis Progression by Regulating Macroautophagy through the PI3K/AKT/mTOR Signaling Pathway
San Jie Tong Mai Fang Protects Against Atherosclerosis Progression by Regulating Macroautophagy through the PI3K/AKT/mTOR Signaling Pathway
Abstract: Many studies have confirmed that macrophage autophagy injury negatively impacts the pat
Anti-inflammatory (Colchicine) Treatment for Secondary Prevention in Coronary Artery Disease: A Milestone has Been Met
Anti-inflammatory (Colchicine) Treatment for Secondary Prevention in Coronary Artery Disease: A Milestone has Been Met
On July 20, 2023, the United States Food and Drug Administration (FDA) approved colchicine 0.5 mg daily as the first anti-...
Cooling Down Inflammation in the Cardiovascular System via the Nicotinic Acetylcholine Receptor
Cooling Down Inflammation in the Cardiovascular System via the Nicotinic Acetylcholine Receptor
Abstract: Inflammation is a major player in many cardiovascular diseases including hypertension,
Oral Oncolytics and Cardiovascular Risk Management and Monitoring
Oral Oncolytics and Cardiovascular Risk Management and Monitoring
Abstract: Oral oncolytic treatment options have expanded over the last decade and have brought to
Advanced Imaging Guiding Early Sodium–Glucose Cotransporter-2 Inhibitor Therapy: An Outlook to the Future?
Advanced Imaging Guiding Early Sodium–Glucose Cotransporter-2 Inhibitor Therapy: An Outlook to the Future?
“Sing me something new” Noel Gallagher1 NEW CHALLENGES We live in the era of the aging society. Owin...
Trimetazidine After Coronary Revascularization: Much Ado About Nothing?
Trimetazidine After Coronary Revascularization: Much Ado About Nothing?
Expectation is the root of all heartache - William Shakespeare Ischemic heart disease (IHD) continu...
Effectiveness and Safety of P2Y12 Inhibitor Pretreatment for Primary PCI in STEMI: Systematic Review and Meta-analysis
Effectiveness and Safety of P2Y12 Inhibitor Pretreatment for Primary PCI in STEMI: Systematic Review and Meta-analysis
Abstract: Dual antiplatelet therapy with aspirin and P2Y12 inhibitors in patients with ST-segment
SGLT2 Inhibitor-pretreated Macrophage Transplantation Improves Adverse Ventricular Remodeling After Acute Myocardial Infarction
SGLT2 Inhibitor-pretreated Macrophage Transplantation Improves Adverse Ventricular Remodeling After Acute Myocardial Infarction
Abstract: Macrophages play an important role in the progression of acute myocardial infarction (A
Impact of Trimetazidine on the Incident Heart Failure After Coronary Artery Revascularization
Impact of Trimetazidine on the Incident Heart Failure After Coronary Artery Revascularization
Abstract: Abnormal myocardial metabolism is a common pathophysiological process underlying ischem
Metformin Alleviates Sepsis-Associated Myocardial Injury by Enhancing AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Signaling Pathway–Mediated Autophagy
Metformin Alleviates Sepsis-Associated Myocardial Injury by Enhancing AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Signaling Pathway–Mediated Autophagy
Abstract: Sepsis-associated myocardial injury is one of the main causes of death in intensive car
Myocardial Protection by Desflurane: From Basic Mechanisms to Clinical Applications
Myocardial Protection by Desflurane: From Basic Mechanisms to Clinical Applications
Abstract: Coronary heart disease is an affliction that is common and has an adverse effect on pat
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