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Transition metal-catalyzed redox-neutral 1,3-dienylation of propargylic esters and divergent synthesis
1,3-Dienes are important scaffolds that extensively exist in natural products and bioactive molecules. They are also valua...
Phosphine-Controlled Divergent Reactions of MBH-Carbonates with Azaheptafulvenes: Access to o-Anilinyl diene and Benzazepine Derivatives
We disclosed a phosphine catalysts controlled divergent cascade reaction of MBH-carbonates with azaheptafulvenes. In the p...
18F-Labelling of Nitrogen-containing Aryl Boronates − Anti-cancer Drug Melflufen as a Case Study
18F-Labelling of nitrogen-containing arenes via copper mediated radiofluorination (CMRF) was investigated. The studies tar...
A Cucurbit[8]uril-mediated Host-guest Complex for Red Light Photocatalysis
A red light supramolecular photocatalytic system is developed by fabricating a cucurbit[8]uril-mediated 3:2 host-guest com...
Asymmetric Synthesis of (Aza)flavanones by the Evolution of CarOx Ligands
Amino-pyridine-oxazoline (NHPyOx) is conceived as an unprecedented model via the core-emulating optimization of CarOx liga...
Photoredox copper-catalyzed regioselective syntheses of allenols via HAT-mediated propargyl radical generation
Selectivity control of the reactions of propargylic and/or allenylic radicals remains particularly elusive. Here, a visibl...
Chiral synthetic unprecedented spiro[indoline-2,3'-thiophen]-3-ones via organocatalytic asymmetric sulfa-Michael/aldol cascade reaction
An asymmetric sulfa-Michael/aldol cascade reaction of 2-ylideneoxindoles with 1,4-dithiane-2,5-diol catalyzed by squaramid...
Design, Synthesis and Application of Bipyridine-N,N’-dioxides Catalysts in Asymmetric Synthesis of Chiral Cyclopropanes
A novel type of highly efficient chiral C2-symmetric bipyridine-N,N’-dioxides ligands prepared from L-octahydroindole-2-ca...
A pillar[5]arene-based three-component supramolecular copolymer for the fluorescence detection of spermine
The supramolecular polymerization of a bis-pillar[5]arene dicarboxylic acid monomer (H) in the presence of a mixture of co...
Catalyst-Free C-H Methylation of Heteroarenes Enabled by Electron Donor-Acceptor Complex Photoactivation
An efficient, additive- and catalyst -free, visible-light-driven radical C-H methylation of heteroarenes (including quinox...
Well-Defined Chiral Dinuclear Copper-Catalyzed Tandem Asymmetric Propargylic Amination-Carboxylative Cyclization Sequence to Chiral 2-Oxazolidinone Derivatives
We report a novel strategy for the synthesis of chiral 2-oxazolidinones via a dinuclear copper-catalyzed asymmetric propar...
The general method for E-selective olefination of acylsilanes with isocyanides via silver catalysis
Trisubstituted alkenes are valuable intermediates in synthetic organic chemistry. The olefination of acylsilanes is expect...
Visible-Light-Promoted Catalytic Epoxidation of Alkenes under Metal-Free Conditions
A new practical approach for mild olefin epoxidations has been developed through visible-light-promoted photoredox catalys...
Photoredox-catalyzed bisarylation of Bromonitroalkanes enabled by the dual role of nitro functionality: synthesis of bis(indolyl)methanes as promising α-glucosidase inhibitors
Disclosed herein is an interesting photoredox catalyzed direct bisarylation of Bromonitroalkanes with 2-Arylindoles to pro...
Visualizing in-field detection of HCV using One-pot RT-RAA-CRISPR/Cas12a platform
Hepatitis C, one of the major infectious diseases posing a serious threat to human health, contributes a significant disea...
Porous boron-doped graphitic carbon nitride-based label-free electrochemical immunoassay of vascular endothelial cadherin
As a main connecting protein between endothelial cells, vascular endothelial cadherin (CD144) is involved in regulating va...
Direct comparison of colorimetric signal amplification techniques in lateral flow immunoassays
The lateral flow immunoassay (LFIA) is widely embraced for point-of-care testing, but its limit of detection (LoD) falls s...
A Sensitive, Rapid and Cost-Effective RP-HPLC-UV Method for Detection and Quantification of Bedaquiline in Physiological fluid (pH 7.4).
Bedaquiline, a highly lipophilic molecule, is used in the treatment regimen of multi-drug resistant tuberculosis. A rare c...
A disposable homemade screen printed electrode for famotidine analysis using computer-designed molecularly imprinted polymer based on MWCNT-Fe3O4 nanocomposite in simulated real samples
A home-made screen printed electrode (SPE) was designed with magnetic multi-walled carbon nanotube (MWCNT-Fe3O4) and molec...
A highly sensitive SERS sensor based on PVDF/Au nanofibers for trace analysis of nitrite ions
Nitrite ions present a significant risk to both environmental and human health, necessitating precise and sensitive detect...
Discrimination of serum samples of prostate cancer and benign prostatic hyperplasia with 1H-NMR metabolomics
Prostate cancer continues to be a prominent health concern for men globally. Current screening techniques, primarily the p...
The Preparation of Fluorescence Dual-Modality Nanosensor for Discrimination and Determination of Biothiols in Real Sample and Its Practical Detection Kit
Biothiols widely exist in living organisms and have a crucial function in the human body for maintaining redox balance. It...
A polar viscosity-sensitive fluorescent probe with large Stokes shifts for simultaneous imaging of lipid droplets and lysosomes in tobacco leaf vein cells and biological systems
Lipid droplets (LDs) and lysosomes were dynamic organelles present in most eukaryotic cells that were interconnected and w...
Development of a novel and useful methodology for the simultaneous analysis of multiclass contaminants in bovine fat
The instrumental development of tandem mass spectrometers fosters the actual trend in the trace analysis of organic compou...
Coaxial burner system for solid-sample flame emission spectroscopy
We present a burner system to analyze solid, inflammable samples by flame emission spectroscopy without requiring any samp...
Electrochemical determination of captopril using disposable graphite electrode modified with a molecularly imprinted film, accompanied by a ratiometric read-out
In this research paper, a novel 'signal on-off' ratiometric-based electrochemical platform was developed for the s...
Production and characterization of collagen-blended electrospun nanofiber matrix for arginase immobilization
Enzyme immobilization onto nanofiber matrices presents a promising avenue for various biotechnological applications. In th...
A Multifunctional Nanoporous Carbon Platform Derived from Zeolitic Imidazolate Framework for Sensing and Enzyme-like Catalyst
Nanoporous carbon materials have gained significant attention in the fields of sensing and catalysts due to their unique r...
Highly Efficient Nano-octahedral Au/γ-Fe2O3 Catalyst Synthesized by Dealloying Combined with Calcination for Low-Temperature CO Oxidation
Environmental pollution, especially air pollution, has become a critical issue requiring prompt resolution. Herein, we hav...
Construction of an off-on fluorescence sensing platform for FRET-based detection of coumarin in cosmetic samples
2-hydroxypropyl-β-Cyclodextrin (2-Hp-β-CD) -functionalized CdTe quantum dots (QDs) were used for coumarin-sensing with hig...
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