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Interleukin-6 drives endothelial glycocalyx damage in COVID-19 and bacterial sepsis
Interleukin-6 drives endothelial glycocalyx damage in COVID-19 and bacterial sepsis
Damage of the endothelial glycocalyx (eGC) plays a central role in the development of vascular hyperpermeability and organ...
2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinases
2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinases
Angiogenesis is a crucial process in the progression of various pathologies, like solid tumors, wet age-related macular de...
Evidence of premature vascular dysfunction in young adults who regularly use e-cigarettes and the impact of usage length
Evidence of premature vascular dysfunction in young adults who regularly use e-cigarettes and the impact of usage length
Electronic (e-) cigarettes are increasingly popular tobacco products on the US market. Traditional tobacco products are kn...
Connective tissue disorders in COVID-19: Reply to “People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing”
Connective tissue disorders in COVID-19: Reply to “People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing”
Connective tissue serves as a framework for other tissues and organs, supporting their functions, shielding them from harm...
Group XIV C-type lectins: emerging targets in tumor angiogenesis
Group XIV C-type lectins: emerging targets in tumor angiogenesis
C-type lectins, distinguished by a C-type lectin binding domain (CTLD), are an evolutionarily conserved superfamily of gly...
A high-resolution view of the heterogeneous aging endothelium
A high-resolution view of the heterogeneous aging endothelium
Vascular endothelial cell (EC) aging has a strong impact on tissue perfusion and overall cardiovascular health. While stud...
Vascularized organoid-on-a-chip: design, imaging, and analysis
Vascularized organoid-on-a-chip: design, imaging, and analysis
Vascularized organoid-on-a-chip (VOoC) models achieve substance exchange in deep layers of organoids and provide a more ph...
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors
Heterozygous activin receptor-like kinase 1 (ALK1) mutations are associated with two vascular diseases: hereditary hemorrh...
Correction: Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization
Correction: Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Systemic glucocorticoids use in post-COVID-syndrome patients does not affect retinal microcirculation
Systemic glucocorticoids use in post-COVID-syndrome patients does not affect retinal microcirculation
We want to thank Peng et. al for the very thoughtful and important comments on our previous publication. They postulated t...
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations
Current treatments of brain arteriovenous malformation (BAVM) are associated with considerable risks and at times incomple...
IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice
IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice
Retinopathy of prematurity (ROP), which often presents with bronchopulmonary dysplasia (BPD), is among the most common mor...
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by the development of arteriove...
Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endothelium
Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endothelium
Regenerative capabilities of the endothelium rely on vessel-resident progenitors termed endothelial colony forming cells (...
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation
Aging is a natural process associated with chronic inflammation in the development of vascular dysfunction. We hypothesize...
Correction: Impact of renal denervation on quality of life (How does renal denervation contribute to improving hypertension treatment affected by poor medication adherence?)
Authors and AffiliationsDepartment of Cardiology and Cardiovascular Center, Imamura Hospital, Tosu, Saga, JapanKeisuke Oka...
Involvement of hydrogen sulfide in the pathogenesis of ischemic stroke-induced paroxysmal sympathetic hyperactivity
Perkes IE, Menon DK, Nott MT, Baguley IJ. Paroxysmal sympathetic hyperactivity after acquired brain injury: a review of di...
Artificial light at night affects the daily profile of pulse pressure and protein expression in the thoracic aorta of rats
Artificial light at night affects the daily profile of pulse pressure and protein expression in the thoracic aorta of rats
Artificial light at night (ALAN) disrupts 24-h variability of blood pressure, but the molecular mechanisms underlying thes...
Best reviewers of Hypertension Research 2023
Best reviewers of Hypertension Research 2023
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
Intelligent Assist Office Blood Pressures (IOBP) versus awake ambulatory monitoring and conventional auscultatory office readings in Chinese primary medical institutions
Intelligent Assist Office Blood Pressures (IOBP) versus awake ambulatory monitoring and conventional auscultatory office readings in Chinese primary medical institutions
To practice standardized office blood pressure (OBP) measurement guidelines pragmatically, we developed an intelligent ass...
Association of pulse pressure and mean blood pressure to frailty, sarcopenia, and cognitive dysfunction in elderly outpatients with history of hypertension
Association of pulse pressure and mean blood pressure to frailty, sarcopenia, and cognitive dysfunction in elderly outpatients with history of hypertension
This study aimed to evaluate the relationship between pulse pressure (PP) and sarcopenia, frailty, and cognitive function ...
Relationship between 2nd-generation angiotensin receptor blockers and the risk of hypotension in COVID-19 patients admitted to hospital
Relationship between 2nd-generation angiotensin receptor blockers and the risk of hypotension in COVID-19 patients admitted to hospital
It has not yet been established whether angiotensin II receptor blockers (ARB), statins, and multiple drugs affect the sev...
Combined effects of blood pressure and glucose status on the risk of chronic kidney disease
Combined effects of blood pressure and glucose status on the risk of chronic kidney disease
This study aimed to assess the combined effects of blood pressure (BP) and glucose status on chronic kidney disease (CKD) ...
New guidelines and therapeutic updates for the management of lupus nephritis
New guidelines and therapeutic updates for the management of lupus nephritis
Purpose of review Systemic lupus erythematosus (SLE) can be a devastating condition, striking you
Novel indications for referral and care for simultaneous liver kidney transplant recipients
Novel indications for referral and care for simultaneous liver kidney transplant recipients
Purpose of review Kidney dysfunction is challenging in liver transplant candidates to determine w
Deep learning applications for kidney histology analysis
Deep learning applications for kidney histology analysis
Purpose of review Nephropathology is increasingly incorporating computational methods to enhance
IgA vasculitis nephritis: insights from kidney biopsies
IgA vasculitis nephritis: insights from kidney biopsies
Purpose of review To present findings indicating the value of kidney biopsy in assessing prognosi
Biopsy-based transcriptomics in the diagnosis of kidney transplant rejection
Biopsy-based transcriptomics in the diagnosis of kidney transplant rejection
Purpose of review The last year has seen considerable progress in translational research explorin
New therapies for immunoglobulin A nephropathy: what's the standard of care in 2023?
New therapies for immunoglobulin A nephropathy: what's the standard of care in 2023?
Purpose of review As the most common primary glomerulonephritis, immunoglobulin A (IgA) nephropat
Has the time come for age-adapted glomerular filtration rate criteria to define chronic kidney disease: how soon is now?
Has the time come for age-adapted glomerular filtration rate criteria to define chronic kidney disease: how soon is now?
Purpose of review The conventional definition of chronic kidney disease (CKD) primarily relies on
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