SCI时时刷

search
+
Genome-editing medicinal products: the EMA perspective
Genome-editing medicinal products: the EMA perspective
Discover the world’s best science and medicine | Nature.com
FDA approves Merck & Co’s pulmonary arterial hypertension drug sotatercept
FDA approves Merck & Co’s pulmonary arterial hypertension drug sotatercept
Discover the world’s best science and medicine | Nature.com
The landscape of small-molecule prodrugs
The landscape of small-molecule prodrugs
Prodrugs are derivatives with superior properties compared with the parent active pharmaceutical ingredient (API), which u...
Novel drug targets in 2023
Discover the world’s best science and medicine | Nature.com
RNAi-based drug design: considerations and future directions
RNAi-based drug design: considerations and future directions
More than 25 years after its discovery, the post-transcriptional gene regulation mechanism termed RNAi is now transforming...
Integrating QSAR modelling and deep learning in drug discovery: the emergence of deep QSAR
Integrating QSAR modelling and deep learning in drug discovery: the emergence of deep QSAR
Quantitative structure–activity relationship (QSAR) modelling, an approach that was introduced 60 years ago, is wide...
Extracellular targeted protein degradation: an emerging modality for drug discovery
Extracellular targeted protein degradation: an emerging modality for drug discovery
Targeted protein degradation (TPD) has emerged in the past decade as a major new drug modality to remove intracellular pro...
Top product forecasts for 2024
Discover the world’s best science and medicine | Nature.com
Upcoming market catalysts in Q1 2024
Upcoming market catalysts in Q1 2024
Discover the world’s best science and medicine | Nature.com
FDA approves first chikungunya vaccine
Discover the world’s best science and medicine | Nature.com
PROTAC in clinic for autoimmune skin disease
PROTAC in clinic for autoimmune skin disease
Discover the world’s best science and medicine | Nature.com
Gene therapy zeroes in on Parkinson disease brain circuits
Gene therapy zeroes in on Parkinson disease brain circuits
Discover the world’s best science and medicine | Nature.com
FDA approves first-in-class AKT inhibitor
Discover the world’s best science and medicine | Nature.com
A decade of HCV drugs
A decade of HCV drugs
Discover the world’s best science and medicine | Nature.com
Antibodies achieve leptin balancing act
Antibodies achieve leptin balancing act
Discover the world’s best science and medicine | Nature.com
γ-secretase inhibitor notches first approval
Discover the world’s best science and medicine | Nature.com
De-risking rare disease acquisitions: a win–win–win for patients, biotech and investors
Discover the world’s best science and medicine | Nature.com
tRNA therapeutics for genetic diseases
tRNA therapeutics for genetic diseases
Transfer RNAs (tRNAs) have a crucial role in protein synthesis, and in recent years, their therapeutic potential for the t...
CAAR T cells to treat encephalitis
Discover the world’s best science and medicine | Nature.com
A safer polyene antifungal
Discover the world’s best science and medicine | Nature.com
USP30 inhibition protects dopaminergic neurons
Discover the world’s best science and medicine | Nature.com
Open-science drug discovery for COVID-19
Discover the world’s best science and medicine | Nature.com
Antibodies combat Gram-negative pathogen
Antibodies combat Gram-negative pathogen
Discover the world’s best science and medicine | Nature.com
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
Diseases associated with chronic inflammation constitute a major health burden across the world. As central instigators of...
Tailor made: the art of therapeutic mRNA design
Tailor made: the art of therapeutic mRNA design
mRNA medicine is a new and rapidly developing field in which the delivery of genetic information in the form of mRNA is us...
A call to adapt the regulation of HLA testing for T cell receptor-based therapeutics
Current regulation of T cell receptor (TCR)-based therapeutics may require repeated testing of patients for specific HLA a...
The renal cell carcinoma drug market
The renal cell carcinoma drug market
Discover the world’s best science and medicine | Nature.com
Targeting synapse function and loss for treatment of neurodegenerative diseases
Targeting synapse function and loss for treatment of neurodegenerative diseases
Synapse dysfunction and loss are hallmarks of neurodegenerative diseases that correlate with cognitive decline. However, t...
CRISPR gets the glory in landmark approval, but haemoglobin research made it possible
CRISPR gets the glory in landmark approval, but haemoglobin research made it possible
Stuart Orkin, of Harvard Medical School and HHMI, discusses how the discovery of BCL11A paved the way for Vertex and CRISP...
The pipeline and market for migraine drugs
The pipeline and market for migraine drugs
Discover the world’s best science and medicine | Nature.com
阅读更多
format_indent_increase