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Engineering novel adeno-associated viruses (AAVs) for improved delivery in the nervous system
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Microbial metabolite-receptor interactions in the gut microbiome
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Therapeutic synthetic anion transporters
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Drug discovery targeting Nav1.8: Structural insights and therapeutic potential
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Designing small-molecule and macromolecule sensors for imaging redox-active transition metal signaling
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Synthetic transporters for oxoanions
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Transferring enzyme features to molecular CO2 reduction catalysts
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Catalyzing the future: recent advances in chemical synthesis using enzymes
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Recent advances in the expanding genetic code
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Corrigendum to “Compounds for selective translational inhibition” [Curr Opin Chem Biol 69 (2022) 102158]
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Advances in acid-degradable and enzyme-cleavable linkers for drug delivery
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Synthetic ion channels in biomembranes
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Forty sites of TRP channel regulation
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Foldamer-mediated transport across phospholipid bilayers
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Development of novel indicators and molecular systems for calcium sensing through protein engineering
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Discovering microbiota functions via chemical probe incorporation for targeted sequencing
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Engineered metallobiocatalysts for energy–relevant reactions
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Illuminating anions in biology with genetically encoded fluorescent biosensors
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Corrigendum to “Drug discovery targeting Nav1.8: Structural insights and therapeutic potential” [Curr Opin Chem Biol 83 (2024) 102538]
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Evolution and function of chromatin domains across the tree of life
Evolution and function of chromatin domains across the tree of life
The genome of all organisms is spatially organized to function efficiently. The advent of genome-wide chromatin conformati...
Diverse anti-NMDAR autoantibodies from individuals with encephalitis
Diverse anti-NMDAR autoantibodies from individuals with encephalitis
Autoantibodies targeting glutamatergic N-methyl-d-aspartic acid receptors (NMDARs) are found in people with anti-NMDAR enc...
A lesson in symmetry
A lesson in symmetry
Duarte, J. M., Dutta, S., Goodsell, D. S. & Burley, S. K. Emerg. Top. Life Sci. 6, 231–243 (2022).Article  CAS  ...
Looking back at the timely launch of Nature Structural Biology in 1994
Structural biology has continued to advance over the past decades, owing to the development of improved and new technologi...
Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism
Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism
The CorA/Mrs2 family of pentameric proteins are cardinal for the influx of Mg2+ across cellular membranes, importing the c...
Structure and function of the human mitochondrial MRS2 channel
Structure and function of the human mitochondrial MRS2 channel
The human mitochondrial RNA splicing 2 protein (MRS2) has been implicated in Mg2+ transport across mitochondrial inner mem...
Supporting structural biologists in Africa requires resources and capacity building
E.N. is funded by the Wellcome Trust (grant number 222999/Z/21/Z) and is a recipient of the Google award for “Support for ...
Determining the optimum number of cycles for calculating joint coordination and its variability during running at different speeds: A timeseries analysis
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A split-belt instrumented treadmill with uneven terrain
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Breaststroke and butterfly intercycle kinematic variation according to different competitive levels with Statistical Parametric Mapping analysis
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Firefighter helmets and cervical intervertebral Kinematics: An OpenSim-Based biomechanical study
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