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A Review on the Treatment and Diagnosis of Systemic Lupus Erythematosus Using Nanoparticle Systems
A Review on the Treatment and Diagnosis of Systemic Lupus Erythematosus Using Nanoparticle Systems
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease characterized by inflammation due to autoan...
Formulation Optimization and in Vitro–in Vivo Evaluation of Alpha Lipoic Acid-Loaded Lipid–Polymer Hybrid Nanoparticles Via Design of Experiments
Formulation Optimization and in Vitro–in Vivo Evaluation of Alpha Lipoic Acid-Loaded Lipid–Polymer Hybrid Nanoparticles Via Design of Experiments
Alpha lipoic acid (ALA) is a natural compound that has recently gained attention for its anti-inflammatory potential. ALA ...
Optimization of Risperidone and Quercetin Solid Lipid Nanoparticles Loaded Nasal Insitu Gel by Design Expert and Quality by Design Approach
Optimization of Risperidone and Quercetin Solid Lipid Nanoparticles Loaded Nasal Insitu Gel by Design Expert and Quality by Design Approach
The objective of the current study is synthesis and optimization of Nasal Insitu Gel loaded with Risperidone (RIS) and Que...
Preparation and Evaluation of N-Acetyl D-Glucosamine Ethosomal Gel for the Treatment of Hyperpigmentation
Preparation and Evaluation of N-Acetyl D-Glucosamine Ethosomal Gel for the Treatment of Hyperpigmentation
N-acetyl D-glucosamine (NAG) holds clinical significance in treating hyperpigmentation through its ability to inhibit mela...
Current Status of Development of Oral Formulations Combining Omega-3 Fatty Acids and Statin Ingredients and Prospects for New Formulations
Current Status of Development of Oral Formulations Combining Omega-3 Fatty Acids and Statin Ingredients and Prospects for New Formulations
Omega-3 fatty acids (O3FA) and statins effectively reducing the levels of triglycerides (TG) and low-density lipoprotein c...
Optimizing Torasemide Gastroretentive In Situ Gel: Integration Of Central Composite Design
Optimizing Torasemide Gastroretentive In Situ Gel: Integration Of Central Composite Design
Torasemide is a diuretic used to treat heart failure, edema, liver and kidney diseases, and hypertension.However, its poor...
“Enhancing Pharmaceutical Accessibility: Evaluating the Impact of Competitive Generic Therapy Exclusivity on Rapid Access of Generics into the U.S. Market (2019–2024)”
“Enhancing Pharmaceutical Accessibility: Evaluating the Impact of Competitive Generic Therapy Exclusivity on Rapid Access of Generics into the U.S. Market (2019–2024)”
The affordability and accessibility of generic medications drive their dominance in the U.S. market. Competitive Generic T...
Formulation of Nanogel Loaded with -Incorporated Silver Nanoparticles: A Bio-Inspired Approach to Rheumatoid Arthritis Therapy
Formulation of Nanogel Loaded with -Incorporated Silver Nanoparticles: A Bio-Inspired Approach to Rheumatoid Arthritis Therapy
This study aims to revolutionize rheumatoid arthritis (RA) treatment by developing an optimized silver nanoparticle (AgNP)...
A Tolerance-based Approach for Validating Analytical Methods Using Design of Experiments
A Tolerance-based Approach for Validating Analytical Methods Using Design of Experiments
Statistically reliable analytical method validation is essential in pharmaceutical manufacturing to ensure accurate and re...
Design, Development and Evaluation of Polyherbal Lollipops Formulation for the Treatment of Oral Thrush and Periodontal Disease
Design, Development and Evaluation of Polyherbal Lollipops Formulation for the Treatment of Oral Thrush and Periodontal Disease
The present investigation aims to formulate a polyherbal lollipops incorporating Neem (Azadirachta indica), Clove (Syzygiu...
Development of Chitosan-Based Microencapsulation System for Alkaloids: A Novel Approach for Alzheimer’s Disease Treatment
Development of Chitosan-Based Microencapsulation System for Alkaloids: A Novel Approach for Alzheimer’s Disease Treatment
We developed a novel chitosan-based microencapsulation system for Mitragyna speciosa alkaloids to enhance their therapeuti...
Investigation of the Synergistic Antibacterial Properties of a Gel Formulated from Green-Synthesized Chitosan-Coated Copper Oxide Nanocomposite
Investigation of the Synergistic Antibacterial Properties of a Gel Formulated from Green-Synthesized Chitosan-Coated Copper Oxide Nanocomposite
Pathogenic bacteria are responsible for the increase of infectious diseases throughout the world, and the development of n...
First Time Exploration of Few Novel Molecules from Oxidative Degradation of Raw and Tableted Quetiapine and Unveiling Their Toxico-Pharmacological Potentials for Future Drug Discovery
First Time Exploration of Few Novel Molecules from Oxidative Degradation of Raw and Tableted Quetiapine and Unveiling Their Toxico-Pharmacological Potentials for Future Drug Discovery
Quetiapine (QUE) is an FDA approved antimanic and antischizophrenic active pharmaceutical ingredient (API). However, queti...
Cell and Gene Therapy Products: Navigating the Regulatory Landscape of Paradigm Approvals in the US (2020 to 2024)
Cell and Gene Therapy Products: Navigating the Regulatory Landscape of Paradigm Approvals in the US (2020 to 2024)
The purpose of this research is to analyze regulatory approvals of Cell and Gene Therapy Products by the FDA from 2020 to ...
Identification and Predictive Analysis of Revenue Determinants in the Pharma Industry: A Longitudinal Analysis of Financial, Regulatory and Pipeline Data
Identification and Predictive Analysis of Revenue Determinants in the Pharma Industry: A Longitudinal Analysis of Financial, Regulatory and Pipeline Data
Maintaining positive revenue performance and R&D productivity is crucial for the pharma industry, therefore identi...
Formulation and Evaluation of Immediate-Release Quetiapine Fumarate Tablets Via Twin-Screw Melt Granulation
Formulation and Evaluation of Immediate-Release Quetiapine Fumarate Tablets Via Twin-Screw Melt Granulation
This study aimed to develop immediate-release Quetiapine Fumarate (QTF) tablets using twin-screw melt granulation (TSMG), ...
Conjugate Delivery of D-Cycloserine and Moxifloxacin via Hydrolysable Cross Linkers -Mesoporous Silica Nanoparticles for Synergistic Effect on Multiple Drug Resistant on Tuberculosis
Conjugate Delivery of D-Cycloserine and Moxifloxacin via Hydrolysable Cross Linkers -Mesoporous Silica Nanoparticles for Synergistic Effect on Multiple Drug Resistant on Tuberculosis
The rise of multidrug-resistant tuberculosis (MDR-TB) poses a significant challenge to global health. This study aimed to ...
Graphene Oxide Nanosheets Incorporated Jasmine Floral Wax and Castor Oil-Based Thermoreversible Oleogel for Improved Corneal Permeation of Ketoconazole: Characterization and Antifungal Study
Graphene Oxide Nanosheets Incorporated Jasmine Floral Wax and Castor Oil-Based Thermoreversible Oleogel for Improved Corneal Permeation of Ketoconazole: Characterization and Antifungal Study
The targeted delivery of drugs to ocular tissue has garnered significant attention for treating ocular diseases. Tradition...
Development and Characterization of an Ibuprofen-Salicylic Acid Co-crystal with Improved Solubility
Development and Characterization of an Ibuprofen-Salicylic Acid Co-crystal with Improved Solubility
Ibuprofen is a widely used non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. However...
Proactive Approaches to cGMP Compliance: Insights and Key Takeaways from USFDA Warning Letters to Pharmaceutical Industries Between 2019 and 2024
Proactive Approaches to cGMP Compliance: Insights and Key Takeaways from USFDA Warning Letters to Pharmaceutical Industries Between 2019 and 2024
This study aims to meticulously analyse the trends and recurrent challenges that emerge from Warning Letters (WLs) issued ...
Assessment of the Effect of Microneedle Pretreatment on Permeation of Hydrophilic and Hydrophobic Drugs Through Burn Eschar
Assessment of the Effect of Microneedle Pretreatment on Permeation of Hydrophilic and Hydrophobic Drugs Through Burn Eschar
Here, utilizing of microneedle roller as a physical enhancer of drug permeation through third-degree burn eschar has been ...
Increasing the Stability of Pellets Containing Lycopene by Using Dual-Coating
Increasing the Stability of Pellets Containing Lycopene by Using Dual-Coating
Lycopene (LYC) is a natural carotenoid, which has antioxidant, anti-inflammatory and anti-cancer properties. Nevertheless,...
Formulation, Evaluation and Optimization of Acitretin Loaded Transethosomes for the Management of Psoriasis
Formulation, Evaluation and Optimization of Acitretin Loaded Transethosomes for the Management of Psoriasis
Psoriasis is a chronic inflammatory skin disorder characterized by the development of red, scaly patches (National Psorias...
Insight into Binding and Interaction of Docking, Dynamics and Network Pharmacology to Explore the Target on Cancer Inhibitors
Insight into Binding and Interaction of Docking, Dynamics and Network Pharmacology to Explore the Target on Cancer Inhibitors
The bioefficacy of accessible chemical structures has been established, leading to some optimization to address these cons...
Formulation, Optimization and In Vitro Studies of Flutamide-loaded Nanostructured Lipid Carrier Based Oral Drug Delivery for Enhanced Anticancer Activity
Formulation, Optimization and In Vitro Studies of Flutamide-loaded Nanostructured Lipid Carrier Based Oral Drug Delivery for Enhanced Anticancer Activity
The purpose of this study was to formulate and evaluate nanostructured lipid carriers (NLCs) of the poorly water soluble a...
Accelerated Approval for Cancer Drugs in the United States and the Clinical Evidence Required for Conversion to Regular Approval
Accelerated Approval for Cancer Drugs in the United States and the Clinical Evidence Required for Conversion to Regular Approval
Oncology products often leverage accelerated approval program to seek earlier launches in the United States. Little is kno...
Assessment of the HaLCon® Protein Analyzer for At-Line Titer Measurements in Biomanufacturing Applications
Assessment of the HaLCon® Protein Analyzer for At-Line Titer Measurements in Biomanufacturing Applications
With the increasing demand for intensified processes in biopharmaceutical manufacturing, there is a growing requirement fo...
Development and In-Vitro Characterization of Capsaicin Microsponges Loaded Topical Gels for Management of Arthritis
Development and In-Vitro Characterization of Capsaicin Microsponges Loaded Topical Gels for Management of Arthritis
Arthritis is the one of the leading causes of disability among a large group of population. It is a slowly progressive dis...
Improving Continuous Loss-in-weight Feeding Accuracy by a Novel Hopper Design
Improving Continuous Loss-in-weight Feeding Accuracy by a Novel Hopper Design
Powder feeding is a vital unit operation in the continuous manufacturing of pharmaceutical products. Loss-in-weight twin-s...
Improving the Doxorubicin Loading to PLGA Nanoparticles with TOPSIS-Based Taguchi Design Approach: Effect of the Water Phase
Improving the Doxorubicin Loading to PLGA Nanoparticles with TOPSIS-Based Taguchi Design Approach: Effect of the Water Phase
PLGA nanoparticles are one of the most investigated drug delivery systems among all polymeric nanoparticles. Although ther...
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