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Embryonic and larval zebrafish models for the discovery of new bioactive compounds against TB
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P-glycoprotein (P-gp)-driven cancer drug resistance: biological profile, non-coding RNAs, drugs and nanomodulators
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Clinical strategies with antibody–drug conjugates as potential modifications for virotherapy
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Targeted protein degradation: current molecular targets, localization, and strategies
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MicroRNAs and therapeutic potentials in acute and chronic cardiac disease
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On the pivotal role of drug discovery in sustainable EU pharma reform
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Innovative Strategies in Cancer Treatment: Harnessing Cuproptosis and Nanotechnology for Targeted Therapy
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Promoting the social implementation of digital and mobile health: effects of regulation on user and non-user behavior in East Asia
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Chemical coverage of human biological pathways
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Exploration of inhibitors targeting KIF18A with ploidy-specific lethality
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Machine learning and natural language processing in clinical trial eligibility criteria parsing: a scoping review
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Role of long noncoding RNAs in the regulation of alternative splicing in glioblastoma
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Hit me with your best shot: Integrated hit discovery for the next generation of drug targets
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Repurposing cardiac glycosides for anticancer treatment: a review of clinical studies
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Designed dualsteric modulators: A novel route for drug discovery
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Mechanical network motifs as targets for mechanomedicine
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Targeting eukaryotic elongation factor 2 kinase (eEF2K) with small-molecule inhibitors for cancer therapy
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How health technology assessment can help to address challenges in drug repurposing: a conceptual framework
How health technology assessment can help to address challenges in drug repurposing: a conceptual framework
Drug repurposing faces various challenges that can impede its success. We developed a framework outlining key challenges i...
How successful are AI-discovered drugs in clinical trials? A first analysis and emerging lessons
How successful are AI-discovered drugs in clinical trials? A first analysis and emerging lessons
AI techniques are making inroads into the field of drug discovery. As a result, a growing number of drugs and vaccines hav...
Text summarization with ChatGPT for drug labeling documents
Text summarization with ChatGPT for drug labeling documents
KeywordsChatGPTtext summarizationdocument summarizationnatural language processing (NLP)artificial intelligence (AI)large ...
TPP-based conjugates: potential targeting ligands
TPP-based conjugates: potential targeting ligands
As one of the most significant organelles in eukaryotic cells, mitochondria have a distinctive role and structure in lipid...
A new era of antibody discovery: an in-depth review of AI-driven approaches
A new era of antibody discovery: an in-depth review of AI-driven approaches
Antibodies(p1),(p2),(p3),(p4),(p5),(p6) are Y-shaped proteins produced by plasma B cells, essential for immune defense.(p7...
From GPUs to AI and quantum: three waves of acceleration in bioinformatics
From GPUs to AI and quantum: three waves of acceleration in bioinformatics
BertilSchmidt is tenured full professor of high-performance computing at Johannes Gutenberg University Mainz and an adjunc...
Unleashing the power of generative AI in drug discovery
Unleashing the power of generative AI in drug discovery
AntonioLavecchia Professor of Medicinal Chemistry and Head of the Drug Discovery Laboratory at the Department of Pharmacy,...
Development and therapeutic implications of small molecular inhibitors that target calcium-related channels in tumor treatment
Development and therapeutic implications of small molecular inhibitors that target calcium-related channels in tumor treatment
Intracellular calcium, functioning as a second messenger, plays a pivotal role in regulating fundamental cellular function...
Premix technologies for drug delivery: manufacturing, applications, and opportunities in regulatory filing
Premix technologies for drug delivery: manufacturing, applications, and opportunities in regulatory filing
The ever-evolving field of drug delivery is always in need of novel and cost-effective strategies for the delivery of comp...
Thyroid receptor β: A promising target for developing novel anti-androgenetic alopecia drugs
Thyroid receptor β: A promising target for developing novel anti-androgenetic alopecia drugs
Androgenetic alopecia (AGA), also known as seborrheic alopecia or male pattern baldness, is the most prevalent form of alo...