*Department of Pharmacology and Toxicology, Faculty of Medicine, American University of Beirut, Riad El-Solh, Beirut, Lebanon;

† Department of Cardiology, Kemer Public Hospital, Kemer, Antalya, Turkey;

‡The Cardiovascular, Renal, and Metabolic Diseases Research Center of Excellence, American University of Beirut Medical Center, Riad El-Solh, Beirut, Lebanon;

§Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey;

¶Department of Pharmacology and Toxicology, School of Medicine, University of Mississippi Medical Center, Jackson, MS; and

║Department of Signaling and Cardiovascular Pathophysiology, UMR-S 1180, Inserm, Université Paris-Saclay, France.

Correspondence: Abdullah Kaplan, MD, Kemer Public Hospital, Hastane Cd. No: 9, 07980, Kemer, Antalya, Turkey (e-mail: [email protected]) or Fouad A. Zouein, PhD, FAHA, Department of Pharmacology and Toxicology, American University of Beirut & Medical Center, Riad El-Solh 1107 2020, Beirut-Lebanon (e-mail: [email protected]).

Supported by grants from the American University of Beirut Faculty of Medicine (Grant No. MPP—320145; URB—103949; URB-104262) and by Centre National de la Recherche Scientifique (CNRS) (Grant No. 103507/103487/103941/103944) and by Collaborative Research Stimulus (103556) funds to F. A. Zouein and by MPP—320095 funds to F. A. Zouein.

The authors report no conflicts of interest.

B. Lakkis and L. El-Samadi have contributed equally.