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Identification of proteome-wide and functional analysis of lysine crotonylation in multiple organs of the human fetus
Identification of proteome-wide and functional analysis of lysine crotonylation in multiple organs of the human fetus
Lysine crotonylation (Kcr) is a novel post-translational modification that is important in functional studies. However, ou...
Identification of noval diagnostic biomarker for HFpEF based on proteomics and machine learning
Identification of noval diagnostic biomarker for HFpEF based on proteomics and machine learning
Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome that currently lacks effective biomarkers for...
Plasma proteome analysis of rheumatic patients reveals differences in fingerprints based on cardiovascular history: a pilot study
Plasma proteome analysis of rheumatic patients reveals differences in fingerprints based on cardiovascular history: a pilot study
The risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) is much higher than that in the genera...
Mass-spectrometry based metabolomics: an overview of workflows, strategies, data analysis and applications
Mass-spectrometry based metabolomics: an overview of workflows, strategies, data analysis and applications
Metabolomics, a burgeoning field within systems biology, focuses on the comprehensive study of small molecules present in ...
To explore the molecular mechanism of IRF7 involved in acute kidney injury in sepsis based on proteomics
To explore the molecular mechanism of IRF7 involved in acute kidney injury in sepsis based on proteomics
Acute kidney injury is a common complication of sepsis, and its mechanism is very complicated. The purpose of this study w...
Investigating a novel three-step excitation scheme for the ultra-trace analysis of plutonium via RIMS
Investigating a novel three-step excitation scheme for the ultra-trace analysis of plutonium via RIMS
A novel three-step excitation scheme for the ultra-trace analysis of $$^$$ Pu via resonance ionization mass spectrometry r...
Medium-entropy nanoenzyme with high oxidase-like activity for sensitive detection of interleukin-6 based on ELISA
Medium-entropy nanoenzyme with high oxidase-like activity for sensitive detection of interleukin-6 based on ELISA
Interleukin-6 (IL-6) is an acute phase response protein. Its level rapidly increases in infection, trauma, and acute infla...
Designing the homogeneous competitive bioluminescence-based assay for tick-borne encephalitis virus (TBEV) point-of-care detection
Designing the homogeneous competitive bioluminescence-based assay for tick-borne encephalitis virus (TBEV) point-of-care detection
Tick-borne encephalitis virus (TBEV), a highly pathogenic infectious agent that causes serious damage to the nervous syste...
LC-QTOF-MS/MS for tentative identification of antioxidant peptides in defatted cakes obtained by supercritical CO extraction
LC-QTOF-MS/MS for tentative identification of antioxidant peptides in defatted cakes obtained by supercritical CO extraction
This work tackles a supercritical fluid extraction (SFE) of microalga spirulina (Arthrospira platensis) to recover potenti...
Comprehensive profiling of sulfated phenolic compounds in edible and infesting seaweeds by a dedicated software-assisted platform
Comprehensive profiling of sulfated phenolic compounds in edible and infesting seaweeds by a dedicated software-assisted platform
Seaweeds, comprising green (Chlorophyta), brown (Phaeophyta), and red (Rhodophyta) algae, are recognized as valuable marin...
LC-HRMS analysis of ultrashort- and short-chain PFAS on porous graphitic carbon column and study of accumulation in plants
LC-HRMS analysis of ultrashort- and short-chain PFAS on porous graphitic carbon column and study of accumulation in plants
In this study, a robust LC-HRMS (QTOF) method was developed for the simultaneous determination of ultrashort- and short-ch...
Structural characterization of intra- and intermolecular disulfide bonds in voltage-dependent anion channel 3 (VDAC3) protein from by high-resolution mass spectrometry
Structural characterization of intra- and intermolecular disulfide bonds in voltage-dependent anion channel 3 (VDAC3) protein from by high-resolution mass spectrometry
Voltage-dependent anion channels, the most abundant proteins of the mitochondrial outer membrane, are responsible for the ...
Characterization and metabolic profiling of oxymetholone and methasterone metabolites studied with human liver S9 model using GC-Orbitrap-HRMS for anti-doping purposes
Characterization and metabolic profiling of oxymetholone and methasterone metabolites studied with human liver S9 model using GC-Orbitrap-HRMS for anti-doping purposes
In vitro metabolic models provide a means to circumvent the ethical concerns associated with human administration research...
Synthesis of a novel multifunctional stationary phase derived from diethanolamine, HILIC/RPLC/WAX mixed-mode HPLC applications, and investigation of the retention mechanism
Synthesis of a novel multifunctional stationary phase derived from diethanolamine, HILIC/RPLC/WAX mixed-mode HPLC applications, and investigation of the retention mechanism
Mixed-mode chromatography is increasingly valued for retaining analytes with diverse polarity and charge by integrating hy...
Encapsulating Pt NCs with an AIE effect into a metal–organic framework as a novel fluorescence nanoprobe for discriminatively detecting bisphosphonate drugs
Encapsulating Pt NCs with an AIE effect into a metal–organic framework as a novel fluorescence nanoprobe for discriminatively detecting bisphosphonate drugs
Fluorescent metal organic frameworks (FMOFs) constructed by encapsulating aggregation-induced emission luminogens (AIEgens...
Sustainable and renewable approaches in biomaterial-based integrated dried urine sampling/solid-phase extraction devices for drugs and metabolites: challenges, bioanalytical applications, and future directions
Sustainable and renewable approaches in biomaterial-based integrated dried urine sampling/solid-phase extraction devices for drugs and metabolites: challenges, bioanalytical applications, and future directions
Urine samples are gaining increasing importance as preferred biological matrices in bioanalytical studies due to their non...
Photonic resonator absorption microscopy: why consider metallic and magneto-plasmonic nano-assemblies over bare nanoparticles for digital biosensing?
Photonic resonator absorption microscopy: why consider metallic and magneto-plasmonic nano-assemblies over bare nanoparticles for digital biosensing?
The unique optical interaction of species such as nanomaterials, proteins, viruses, antibodies, microRNA, and exosomes wit...
Screening and optimization of online comprehensive two-dimensional liquid chromatography conditions for the analysis of hospital wastewater
Screening and optimization of online comprehensive two-dimensional liquid chromatography conditions for the analysis of hospital wastewater
Pharmaceutical residues in freshwater systems constitute a growing environmental problem. An important point source of the...
Comparative evaluation of phenyl isothiocyanate derivatization and “dilute-and-shoot” methods for HPLC–MS/MS-based targeted metabolomics analysis of amine-containing metabolites in plasma samples
Comparative evaluation of phenyl isothiocyanate derivatization and “dilute-and-shoot” methods for HPLC–MS/MS-based targeted metabolomics analysis of amine-containing metabolites in plasma samples
Metabolomics, the study of small molecule metabolites in biological systems, is essential for disease diagnosis and biomar...
Plug-based online dilution strategy for achieving 11.6-fold sensitivity enhancement in UPLC-MS/MS analysis of 38 veterinary drug residues
Veterinary drugs have played important roles in modern animal husbandry due to their prevention and treatment of diseases ...
Microfluidic magnetic solid-phase extraction of acetamiprid using dynamically manipulated apta-magnetic sorbents for chromatographic analysis
Chromatographic techniques, renowned for their unparalleled separation resolution and detection sensitivity, have emerged ...
Determination of free melamine content in uncured non-ionic and sulfonated melamine-based resins by reversed-phase and mixed-mode liquid chromatography
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Detection of D-Dopa in levodopa tablets by derivatization coupled with LC-MS/MS
Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders, the pathological depletion of dopamine ...
Column ageing of agarose-based chromatography in industrial lactoferrin purification
Commercial lactoferrin is extracted from bovine milk using cation exchange chromatography with agarose-based Sepharose SP ...
The Dynamic balances in HPLC: An unconventional application of temperature to optimize ionizable solute separations
Over the past decades, high-performance liquid chromatography (HPLC) has become one of the most versatile and widely used ...
Application of gas chromatography with tandem mass spectrometry for analysis of azo dyes extracted from polyester fibers for forensic fiber discrimination
Microfibers represent one of the most significant groups of traces revealed at a crime scene. Due to their high transfer p...
Determination of liquid crystal monomers in environmental water by ultrasound-assisted pH-responsive deep eutectic solvent based homogeneous liquid-liquid microextraction
With the rapid advancement of the information age, electronic products equipped with liquid crystal displays (LCDs) have s...
Small sample data-driven interpretable artificial neural network computation for two-component chromatographic separation process
Chromatography separation is a commonly used separation technique, and the chromatographic elution curve is an important b...
Integration of capillary chromatography columns into a 3D-printed microfluidic multiport valve for miniaturized multi-column chromatography
Driven by the need for smaller and more efficient continuous chromatographic systems, this study explores the feasibility ...
A multitemplate magnetic molecularly imprinted polymer used for highly selective separation and purification of coumarins from Angelica dahurica
Angelica dahurica, a traditional medicinal and food homology plant, belongs to the Umbelliferae family and was documented ...
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