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Gene of the month: DDIT3
Gene of the month: DDIT3
DNA damage-inducible transcript 3 (DDIT3) gene, mapped to the human chromosome 12q13.3, encodes a protein that belongs to ...
Gender distribution in pathology journal editorial boards: a call to action
Gender distribution in pathology journal editorial boards: a call to action
The article by Nguyen et al reveals that Pathology, like other medical specialties, has an underrepresentation of women au...
Gender distribution in surgical pathology journal publications and editorial boards
Gender distribution in surgical pathology journal publications and editorial boards
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Risk assessment in pT1 colorectal cancer
Risk assessment in pT1 colorectal cancer
IntroductionColorectal cancer (CRC) is one of the most common malignancies, resulting in 16 800 deaths in the UK annually....
Expression and correlation of PD-L1 and HER2 in oesophageal squamous cell carcinoma
Expression and correlation of PD-L1 and HER2 in oesophageal squamous cell carcinoma
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Impact of cellular morphology and three-tiered nuclear grade on progression of conventional renal cell carcinoma
Impact of cellular morphology and three-tiered nuclear grade on progression of conventional renal cell carcinoma
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Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens
Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionTriple-negative bre...
Tumour-to-tumour metastasis of breast cancer (donor) and clear cell renal cell carcinoma (recipient): a case report
Tumour-to-tumour metastasis of breast cancer (donor) and clear cell renal cell carcinoma (recipient): a case report
A woman in her late 70s was referred to urology clinic to consider intervention for a biopsy-proven 24 mm WHO/Internationa...
Kinase expression in angiomatoid fibrous histiocytoma: panTRK is commonly expressed in the absence of NTRK rearrangement
Kinase expression in angiomatoid fibrous histiocytoma: panTRK is commonly expressed in the absence of NTRK rearrangement
Angiomatoid fibrous histiocytoma (AFH) is a soft tissue tumour of intermediate (rarely metastasising) malignant potential,...
Efficacy of postmortem CT and tissue sampling in establishing the cause of death in clinical practice: a prospective observational study
Efficacy of postmortem CT and tissue sampling in establishing the cause of death in clinical practice: a prospective observational study
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Non-deletional haemoglobin H (Hb H) disease morphologically masquerading as congenital dyserythropoietic anaemia type II: a diagnostic pitfall
Non-deletional haemoglobin H (Hb H) disease morphologically masquerading as congenital dyserythropoietic anaemia type II: a diagnostic pitfall
Haemoglobin H (Hb H) disease is a form of alpha (α)-thalassaemia where three of the four α-globin gene alleles are deleted...
Implementation of an ISO15189 accredited next-generation sequencing service with the fully automated Ion Torrent Genexus: the experience of a clinical diagnostic laboratory
Implementation of an ISO15189 accredited next-generation sequencing service with the fully automated Ion Torrent Genexus: the experience of a clinical diagnostic laboratory
WHAT IS ALREADY KNOWN ON THIS TOPICThis is a new concept, the implementation of an ISO15189 accredited next-generation seq...
Successful demand management in diagnostic immunology testing
Successful demand management in diagnostic immunology testing
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Modes of assay interference and the effectiveness of serum pretreatment approaches in detection of anti-HLA antibodies
Modes of assay interference and the effectiveness of serum pretreatment approaches in detection of anti-HLA antibodies
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Tocilizumab in chronic active antibody-mediated rejection: rationale and protocol of an in-progress randomized controlled open-label multi-center trial (INTERCEPT study)
Tocilizumab in chronic active antibody-mediated rejection: rationale and protocol of an in-progress randomized controlled open-label multi-center trial (INTERCEPT study)
Chronic active antibody-mediated rejection (caAMR) in kidney transplants is associated with irreversible tissue damage and...
The effects of Phoniatric PREhabilitation in Head and Neck Cancer patients on Aspiration and Preservation of Swallowing (PREHAPS): study protocol of a monocentric prospective randomized interventional outcome-blinded trial
The effects of Phoniatric PREhabilitation in Head and Neck Cancer patients on Aspiration and Preservation of Swallowing (PREHAPS): study protocol of a monocentric prospective randomized interventional outcome-blinded trial
Dysphagia, with its negative impact on life expectancy and quality of life, is a major side effect of head and neck squamo...
Peers plus mobile app for treatment in HIV (PATH): protocol for a randomized controlled trial to test a community-based integrated peer support and mHealth intervention to improve viral suppression among Hispanic and Black people living with HIV
Peers plus mobile app for treatment in HIV (PATH): protocol for a randomized controlled trial to test a community-based integrated peer support and mHealth intervention to improve viral suppression among Hispanic and Black people living with HIV
Significant disparities continue to exist in the HIV care continuum, whereby Hispanic and Black people living with HIV (PL...
Sacral neuromodulation for constipation and fecal incontinence in children and adolescents – study protocol of a prospective, randomized trial on the application of invasive vs. non-invasive technique
Sacral neuromodulation for constipation and fecal incontinence in children and adolescents – study protocol of a prospective, randomized trial on the application of invasive vs. non-invasive technique
A therapeutic effect of sacral neuromodulation (SNM) on fecal incontinence (FI) and quality of life has been proven in adu...
The effect of selenium supplementation on oxidative stress, clinical symptoms and mental health status in patients with migraine: a study protocol for a double-blinded randomized clinical trial
The effect of selenium supplementation on oxidative stress, clinical symptoms and mental health status in patients with migraine: a study protocol for a double-blinded randomized clinical trial
Despite a number of recommended strategies, effective treatment of migraine remains elusive. Given the role of oxidative s...
A new, deep learning–based method for the analysis of autopsy kidney samples used to study sex differences in glomerular density and size in a forensic population
A new, deep learning–based method for the analysis of autopsy kidney samples used to study sex differences in glomerular density and size in a forensic population
Artificial intelligence (AI) is increasingly used in forensic anthropology and genetics to identify the victim and the cau...
Forensic pilot application of rehydrating solutions on human cadaveric skin: what are the effects on hemorrhagic infiltrates?
Forensic pilot application of rehydrating solutions on human cadaveric skin: what are the effects on hemorrhagic infiltrates?
The microscopic evaluation of hemorrhagic infiltrates is crucial in forensic diagnostics, but it proves challenging in cor...
Identifying hypothermia death in a mouse model by ATR-FTIR
Identifying hypothermia death in a mouse model by ATR-FTIR
The identification of hypothermia death (HD) is difficult for cadavers, especially the distinction from death due to alter...
Technical strategy for monozygotic twin discrimination by single-nucleotide variants
Technical strategy for monozygotic twin discrimination by single-nucleotide variants
Monozygotic (MZ) twins are theoretically genetically identical. Although they are revealed to accumulate mutations after t...
Cardiogenic shock in a 28-year-old woman associated with sibutramine use
Cardiogenic shock in a 28-year-old woman associated with sibutramine use
A 28-year-old woman collapsed in her home, and her companion rushed to call emergency services. Upon arrival, a physician ...
Cardiac effects of 5F-Cumyl-PEGACLONE
Cardiac effects of 5F-Cumyl-PEGACLONE
Synthetic cannabinoids become increasingly popular as a supposedly safe and legal alternative to cannabis. In order to cir...
Morphine concentrations in fatalities after palliative treatment of acute burn injury
Morphine concentrations in fatalities after palliative treatment of acute burn injury
The evaluation of a morphine concentration in postmortem blood is routine for a forensic toxicologist. We here report thre...
Forensic age estimation of the knee by post-mortem DR, CT, and MR imaging: a comparative study
Forensic age estimation of the knee by post-mortem DR, CT, and MR imaging: a comparative study
It is believed by many that reference data for age estimation purposes must be imaging-modality specific. A study from our...
Adult age estimation from the sternum using maximum intensity projection images of CT and data mining in a Chinese population
Adult age estimation from the sternum using maximum intensity projection images of CT and data mining in a Chinese population
This study aimed to explore and develop data mining models for adult age estimation based on CT reconstruction images from...
Estimation of ancestry from cranial measurements based on MDCT data acquired in a Japanese and Western Australian population
Estimation of ancestry from cranial measurements based on MDCT data acquired in a Japanese and Western Australian population
The estimation of ancestry is important not only towards establishing identity but also as a required precursor to facilit...
An overview of the heat-induced changes of the chemical composition of bone from fresh to calcined
An overview of the heat-induced changes of the chemical composition of bone from fresh to calcined
When bone is exposed to thermal stress, the chemical composition changes. This affects bone tissue regeneration after surg...
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