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Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes
Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes
Atypical teratoid rhabdoid tumors (ATRTs) are aggressive central nervous system tumors mainly affecting young children. Ex...
The malignant transformation of an atypical angiocentric glioma, MYB-altered
The malignant transformation of an atypical angiocentric glioma, MYB-altered
According to the current World Health Organization classification of central nervous system tumors, the angiocentric gliom...
Gene therapy ameliorates neuromuscular pathology in CLN3 disease
Gene therapy ameliorates neuromuscular pathology in CLN3 disease
CLN3 disease is a neuronopathic lysosomal storage disorder that severely impacts the central nervous system (CNS) while al...
Involvement of membrane palmitoylated protein 6 (MPP6) in synapses of mouse cerebrum
Involvement of membrane palmitoylated protein 6 (MPP6) in synapses of mouse cerebrum
Membrane palmitoylated protein 6 (MPP6), a membrane skeletal protein, is expressed not only in the peripheral nervous syst...
Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia
Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia
Inflammation is a key contributor to the development of preeclampsia. Recent studies suggest that circular RNAs (circRNAs)...
Immunocytochemical detection of proteins within cellular structures inaccessible to specific antibodies
Immunocytochemical detection of proteins within cellular structures inaccessible to specific antibodies
Immunocytochemistry and immunohistochemistry are among the most widely used and valuable methods for localizing and quanti...
Subcellular localization of the P2X4 receptor in sensory hair cells of Wistar rat cochlea
Subcellular localization of the P2X4 receptor in sensory hair cells of Wistar rat cochlea
Our sense of hearing starts in the inner ear organ, the cochlea, which contains two types of auditory hair cells for signa...
HIV-associated preeclampsia: evaluation of lymphangiogenesis in placental bed samples
HIV-associated preeclampsia: evaluation of lymphangiogenesis in placental bed samples
The role of angiogenesis in preeclampsia pathogenesis is widely studied; however, despite the lymphatic vessels’ com...
April In focus in HCB
April In focus in HCB
In the recent “February In focus in HCB” editorial, we highlighted three manuscripts focusing on bone and hard tissues (Ta...
MST1 modulates inflammatory responses by targeting the NF-κB/NLRP3 pathway in LPS-induced acute lung injury
MST1 modulates inflammatory responses by targeting the NF-κB/NLRP3 pathway in LPS-induced acute lung injury
Acute lung injury (ALI) represents a severe respiratory condition. Inflammation is a pivotal factor in the pathogenesis of...
Microtubule nucleation at the Golgi-related membrane organelles of mouse neurons
Microtubule nucleation at the Golgi-related membrane organelles of mouse neurons
Microtubules are often nucleated at non-centrosomal sites in some differentiated cell types. We previously reported that m...
Quantitative analysis of cancer cell morphology using digital holography technology under high temperature stimulation
Quantitative analysis of cancer cell morphology using digital holography technology under high temperature stimulation
In cancer tissue diagnostic studies of clinical medicine, cell morphology is a key indicator for assessing the behavior of...
MOTS-c modulates pancreatic islet function in rats and pigs in vitro
MOTS-c modulates pancreatic islet function in rats and pigs in vitro
MOTS-c is a promising regulator of metabolism and energy homeostasis. While its effects have been studied in cell lines, o...
May In focus in HCB
May In focus in HCB
Fibroblasts have come a long way to be eventually recognized as a most complex cell type of diverse lineage origins and of...
Super-resolution radial fluctuations (SRRF): a versatile and accessible tool for live-cell nanoscopy
Super-resolution radial fluctuations (SRRF): a versatile and accessible tool for live-cell nanoscopy
Super-resolution radial fluctuation (SRRF) microscopy is a novel computational imaging technique that bypasses the optical...
Angiopoietins: multifaceted mediators in the pathogenesis of joint-related disorders
Angiopoietins: multifaceted mediators in the pathogenesis of joint-related disorders
Joint-related diseases often involve multiple aspects of angiogenesis, alterations in the extracellular matrix (ECM), and ...