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Targeting clonal mutations with synthetic microbes
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Warming-up the immune cell engagers (ICEs) era in breast cancer: state of the art and future directions
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A Comprehensive Review and Meta-Analysis of CTC Isolation Methods in Breast Cancer
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Prostate-specific membrane antigen as target for vasculature-directed therapeutic strategies in solid tumors
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A systematic literature review on clonal evolution events preceding relapse in multiple myeloma
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BCMA CAR-T induces complete and durable remission in plasmablastic lymphoma synchronous transformation of chronic lymphocytic leukemia: Case report and literature review
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Skin barrier dysfunction in cutaneous T-cell lymphoma: From pathogenic mechanism of barrier damage to treatment
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Advancing tumor vaccines: Overcoming TME challenges, delivery strategies, and biomaterial-based vaccine for enhanced immunotherapy
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The role of amino acid PET in radiotherapy target volume delineation for adult-type diffuse gliomas: A review of the literature
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Adapted physical activity programs for the prevention and treatment of musculoskeletal pain induced by aromatase inhibitors in non-metastatic breast cancer patient: A scoping review
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KRAS mutations in advanced non-small cell lung cancer: From biology to novel therapeutic strategies
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Nature killer cell for solid tumors: Current obstacles and prospective remedies in NK cell therapy and beyond
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Spectrum and genotyping strategies of “dark” genetic matter in germline susceptibility genes of tumor syndromes
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Role of osimertinib plus brain radiotherapy versus osimertinib single therapy in EGFR-mutated non-small-cell lung cancer with brain metastases: A meta-analysis and systematic review
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Concomitant chemotherapy in trimodal treatment of patients with muscle invasive bladder cancer: A systematic review of prospective trials
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The application of stepped-wedge cluster-randomized controlled trial study designs in oncology settings: A systematic review
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Expedited pathway insights: Unveiling oncology and non-oncology drug approvals and withdrawals of USFDA and EMA
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The prevalence of solid tumors and hematologic malignancies among patients with Down syndrome: A systematic review and meta-analysis
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Association of epigenetic landscapes with heterogeneity and plasticity in pancreatic cancer
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Chemotherapy, immunotherapy, and targeted therapy for osteosarcoma: Recent advancements
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Management of Toxicities Associated with BCMA, GPRC5D, and FcRH5-Targeting Bispecific Antibodies in Multiple Myeloma
Management of Toxicities Associated with BCMA, GPRC5D, and FcRH5-Targeting Bispecific Antibodies in Multiple Myeloma
The introduction of bispecific antibodies is one of the most significant recent advances in the treatment of relapsed/refr...
Systemic Mastocytosis: State of the Art
Systemic Mastocytosis: State of the Art
Since identification of Systemic mastocytosis (SM) as a distinct disease entity by the World Health Organisation (WHO), th...
JAK Inhibitors for Myelofibrosis: Strengths and Limitations
JAK Inhibitors for Myelofibrosis: Strengths and Limitations
The landscape of myelofibrosis (MF) has changed since the discovery of the JAK2 V617F mutation and subsequent development ...
Spatial immunogenomic patterns associated with lymph node metastasis in lung adenocarcinoma
Spatial immunogenomic patterns associated with lymph node metastasis in lung adenocarcinoma
Lung adenocarcinoma (LUAD) with lymph node (LN) metastasis is linked to poor prognosis, yet the underlying mechanisms rema...
Advances in adoptive cellular immunotherapy and therapeutic breakthroughs in multiple myeloma
Advances in adoptive cellular immunotherapy and therapeutic breakthroughs in multiple myeloma
The basic idea of modulating the immune system to better recognize and fight tumor cells has led to the successful introdu...
Vertical targeting of the PI3K/AKT pathway at multiple points is synergistic and effective for non-Hodgkin lymphoma
Vertical targeting of the PI3K/AKT pathway at multiple points is synergistic and effective for non-Hodgkin lymphoma
The phosphatidylinositol 3‑kinase/protein kinase B (PI3K/AKT) signaling pathway is critically active in many cell ty...
Crosstalk between O-GlcNAcylation and ubiquitination: a novel strategy for overcoming cancer therapeutic resistance
Crosstalk between O-GlcNAcylation and ubiquitination: a novel strategy for overcoming cancer therapeutic resistance
Developing resistance to cancer treatments is a major challenge, often leading to disease recurrence and metastasis. Under...
Nuclear porcupine mediates XRCC6/Ku70 S-palmitoylation in the DNA damage response
Nuclear porcupine mediates XRCC6/Ku70 S-palmitoylation in the DNA damage response
The activation of the DNA damage response (DDR) heavily relies on post-translational modifications (PTMs) of proteins, whi...
Molecular profiling of primary renal diffuse large B-cell lymphoma unravels a proclivity for immune-privileged organ-tropism
Molecular profiling of primary renal diffuse large B-cell lymphoma unravels a proclivity for immune-privileged organ-tropism
medRxiv - The Preprint Server for Health Sciences
Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells in vivo
Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells in vivo
medRxiv - The Preprint Server for Health Sciences
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