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Human mesenchymal stem cell therapy: Potential advances for reducing cystic fibrosis infection and organ inflammation
Innovation in cystic fibrosis (CF) supportive care, including implementing new antimicrobial agents, improved physiotherap...
Mesenchymal stem cells in hematology: Therapeutic initiatives and future directions
Volume 38, Issue 1, March 2025, 101613Author links open overlay panel, , , , , AbstractIn recent years, the landscape of h...
Creating a GMP cell processing program: A focus on quality and regulation
Volume 38, Issue 1, March 2025, 101614Author links open overlay panel, , AbstractImplementing current Good Manufacturing P...
Anti-GM-CSF autoantibodies in myeloid leukemias
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multifunctional cytokine integral to the differentiation, p...
The history of cytokines and growth factors development
Volume 38, Issue 1, March 2025, 101612Author links open overlay panel, Highlights•Commercial development of cytokines and ...
Precision Immunomodulation: Understanding and Harnessing Cytokine Pathways to Treat and Prevent Immune-Related Adverse Events (irAEs)
Available online 16 April 2025, 101625Author links open overlay panel, , , Highlights:This manuscript delves into our curr...
Endogenous and exogenous cytokines: An overview and introduction
Cytokines are small proteins, secreted by many cells, including but not limited to immune cells such as lymphocytes and ma...
Clinicopathologic features of primary central nervous system anaplastic large cell lymphoma: a multicenter study identifies age and ALK status as prognostic factors
Clinicopathologic features of primary central nervous system anaplastic large cell lymphoma: a multicenter study identifies age and ALK status as prognostic factors
Anaplastic large cell lymphoma with primary presentation in, and disease limited to, the central nervous system (primary C...
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Chronic myeloid leukemia (CML) typically presents in the chronic phase. The blast crisis phase in CML predominantly compri...
BRAF V600E mutation and high expression of PD-L1 in Rosai-Dorfman disease: case report and review of the literature
BRAF V600E mutation and high expression of PD-L1 in Rosai-Dorfman disease: case report and review of the literature
BRAF V600E mutations are frequently found in histiocytic/dendritic cell neoplasms such as Erdheim-Chester disease (ECD) an...
Mast cell sarcoma with p.D816V mutation and concurrent systemic mastocytosis
Mast cell sarcoma with p.D816V mutation and concurrent systemic mastocytosis
Mast cell sarcoma (MCS) is an extremely rare and aggressive form of mastocytosis characterized by highly atypical mast cel...
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
A 69-year-old with well-controlled HIV was evaluated for persistent cough, in the context of years of fatigue and...
Intraocular bone marrow formation in end-stage phthisis bulbi
Intraocular bone marrow formation in end-stage phthisis bulbi
Funding This study was not supported by any funding. ...
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphomas (PGTL) are exceedingly rare with an estimated incidence of 0.0091 per 100,000 person-year...
A rare case of primary testicular follicular lymphoma in a pediatric patient
A rare case of primary testicular follicular lymphoma in a pediatric patient
Testicular follicular lymphoma (TFL) is an exceedingly rare lymphoma that typically occurs in young male patients and is n...
CD3/CD20/CD45 negative leukemia cutis
CD3/CD20/CD45 negative leukemia cutis
A 56-year-old male presented to the clinic with complaints of multiple skin lesions. A complete blood count (CBC) was not ...
Correction to: CD3/CD20/CD45 negative leukemia cutis
Correction to: CD3/CD20/CD45 negative leukemia cutis
A skin punch biopsy showed fragments of skin with extensive lymphoid infiltrates (Fig.1, A; x20 objective, hematoxylin and...
T-cell lymphoproliferative disorder with a mutation causing a lymphocytic variant of hypereosinophilic-like syndrome without eosinophilia
T-cell lymphoproliferative disorder with a mutation causing a lymphocytic variant of hypereosinophilic-like syndrome without eosinophilia
Lymphocytic variant of hypereosinophilic syndrome (LV-HES) is a rare T-cell lymphoproliferative disorder characterized by ...
A case report and a literature review about central nervous system involvement in monomorphic epitheliotropic intestinal T cell lymphoma
A case report and a literature review about central nervous system involvement in monomorphic epitheliotropic intestinal T cell lymphoma
Monomorphic epitheliotropic intestinal T cell lymphoma (MEITL) is a rare subtype of primary T cell lymphoma of the digesti...
Prognostic outcomes of diffuse large B-cell lymphoma patients with myelocytomatosis oncogene (MYC) and B-cell lymphoma 2 (BCL2) co-expression
Prognostic outcomes of diffuse large B-cell lymphoma patients with myelocytomatosis oncogene (MYC) and B-cell lymphoma 2 (BCL2) co-expression
Double expressor lymphoma (DEL) refers to diffuse large B-cell lymphoma (DLBCL) cases characterized by the overexpression ...
Lifileucel (AMTAGVI) tumor-infiltrating lymphocyte morphology in CellaVision peripheral smear reviews
Lifileucel (AMTAGVI) tumor-infiltrating lymphocyte morphology in CellaVision peripheral smear reviews
Ethical approval Not applicable for a study of this type. ...
Diffuse large B-cell lymphoma with partial low Ki67 proliferation index
Diffuse large B-cell lymphoma with partial low Ki67 proliferation index
We present a case of diffuse large B-cell lymphoma characterized by areas exhibiting unexpectedly low Ki67 staining in a 4...
A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)
A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)
Multiple myeloma is a clonal plasma cell malignancy often characterized by complex cytogenetic abnormalities that influenc...
A deep-learning algorithm (AIFORIA) for classification of hematopoietic cells in bone marrow aspirate smears based on nine cell classes—a feasible approach for routine screening?
A deep-learning algorithm (AIFORIA) for classification of hematopoietic cells in bone marrow aspirate smears based on nine cell classes—a feasible approach for routine screening?
Bone marrow cytology plays a key role for the diagnosis and classification of hematological disease and is often the first...
Lymph node microscopic findings in Wiskott-Aldrich syndrome
Lymph node microscopic findings in Wiskott-Aldrich syndrome
A 20-year-old man with a history of Wiskott-Aldrich syndrome (WAS) underwent excisional biopsy of a femoral lymph&nbsp...
HLA-DR positive acute promyelocytic leukaemia (APML) with cryptic fusion
HLA-DR positive acute promyelocytic leukaemia (APML) with cryptic fusion
We report the case of a 42-year-old female presented with cytopenia and abnormal promyelocytes on blood film. The promyelo...
Chimerism analysis by ABO blood group genotyping with digital droplet PCR
Chimerism analysis by ABO blood group genotyping with digital droplet PCR
Chimerism analysis is an important post-transplant assessment for allogeneic hematopoietic stem cell transplant (HCT) reci...
New classifications of B-cell neoplasms: a comparison of 5th WHO and International Consensus classifications
New classifications of B-cell neoplasms: a comparison of 5th WHO and International Consensus classifications
In 2024, the World Health Organization (WHO) launched a new classification of lymphoid neoplasms, a revision of the previo...
Graft CD8+ T cells for improving event-free survival after T cell-replete haploidentical stem cell transplantation in children with hematological malignancies
Graft CD8+ T cells for improving event-free survival after T cell-replete haploidentical stem cell transplantation in children with hematological malignancies
T cell-replete haploidentical hematopoietic stem cell transplantation (TCR-haplo-HSCT) is a potentially curative therapy f...
Pseudo-Chediak–Higashi inclusions and Auer rods in a case of therapy-related acute monocytic leukemia
Pseudo-Chediak–Higashi inclusions and Auer rods in a case of therapy-related acute monocytic leukemia
Conflict of interest The author has no conflict of interest...
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