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Gas-based therapies in chronic wounds: A scoping review of preclinical and clinical data
IntroductionChronic wounds are injuries that persist beyond expected healing timeframes. Although they have varying aetiol...
Effects of Co-Processed and conventional excipients on content uniformity
Silicification of microcrystalline cellulose (MCC) has previously been shown to have positive effects on the powder’s flow...
Mucus-penetrating archaeolipid nanocarriers delivering Thymus vulgaris essential oil and tobramycin: A multifunctional approach against Pseudomonas aeruginosa biofilms and inflammation
Cystic fibrosis (CF) is an inherited disorder caused by mutations in the gene encoding the cystic fibrosis transmembrane c...
Optimization of intranasal trifluoperazine/SPION-leciplex thermosensitive organogel for depression therapy: Pharmacodynamic and pharmacokinetic comparison of magnet placement effects on brain versus nose
Trifluoperazine (TFP) is an oral antipsychotic agent used to treat depression, agitation, anxiety, schizophrenia, and othe...
Development of Trastuzumab-coupled, siRNA encapsulating mPolyplexes targeting HER2 overexpressing cancer cells
Over the past decades, significant advancements have been made in various medical fields; however, ovarian cancer (OC) rem...
Deciphering protein aggregation in freeze-thaw process: the roles of cold denaturation and shear stress
Freezing and thawing play an important role in the manufacturing, storage, and distribution of biologics. While these proc...
Development of media simulating the properties of human peritoneal fluid and verification of its bio-relevance
Intraperitoneal drug delivery offers a promising strategy for localized treatment of peritoneal tumours and post-surgical ...
Corrigendum to “Dissolving microneedle patches for delivery of amniotic mesenchymal stem cell metabolite products for skin regeneration in UV-aging induced mice” [Eur. J. Pharm. Biopharm. 204 (2024) 114482]
Volume 217, December 2025, 114896Author links open overlay panelAndang Miatmoko a b c, Berlian Sarasitha Hariawan d, Devy ...
Corrigendum to “Film-forming system of optimized tacrolimus-loaded nanostructured lipid carriers for effective topical treatment of atopic dermatitis”. [Eur. J. Pharm. Biopharm. 216, 114871]
Volume 217, December 2025, 114899Author links open overlay panelJin Sil Kang a 1, Young-Guk Na a 1, Minki Jin a 1, Gabsik ...
Analysis of discrepancy in SNEDDS performance for a “brick dust” mebendazole between in-vitro and in-vivo estimation
Exploration for development of more effective drugs by modern technologies has led to many new drug candidates that are po...
Pharmacomagnetography of floating gastroretentive systems in vivo in different prandial states evaluated by AC biosusceptometry
In recent decades, the development of effective therapies with minimal adverse effects has become a major challenge in the...
Synergistic co-processing of heat-moisture treated resistant rice starch with HPMC and Eudragit® S100: A novel multifunctional excipient for direct compression and colon-targeted delivery
The development of colon-targeted drug delivery systems has gained increasing attention due to their potential to improve ...
Nanoparticle-based oral rinses for plaque control: A systematic review of efficacy and safety
Oral diseases, chiefly dental caries, gingivitis, periodontitis, and halitosis, continue to top the list of global health ...
A strategy to prevent ciprofloxacin induced corneal toxicity
Every month thousands of patients are treated with ocular ciprofloxacin, yet crystalline deposits form on the surface of t...
A bedside-savior for insomnia and anxiety disorders: melatonin/buspirone hydrochloride compound oral fast-dissolving film
Insomnia represents the most prevalent clinical sleep disorder, manifesting as either a primary condition or secondary sym...
Development of piperine/HPβCD-loaded PVA-coated iron oxide nanoparticles in in situ gel for enhanced retinal delivery and anti-VEGF activity
Diabetic retinopathy (DR) is a severe diabetes-related complication which occurs due to abnormal blood vessel growth in th...
Review of design strategies for active targeted drug delivery systems for pancreatic cancer
PC is often referred to as the “king of cancers” due to its difficult treatment, low survival rates, and poor prognosis. D...
From empirical exploration to data-driven innovation: The role of artificial intelligence in pharmaceutical taste masking
Taste is one of the five basic human senses, along with sight, touch, hearing, and smell [1], enabling the detection of ch...
Impact of terminal groups on PLGA degradation rate and their role in sustained release of cyproterone acetate
Microspheres are widely utilized as a sustained-release drug delivery system, with several successful commercial products ...
Biomembrane-Derived vesicles for targeted cancer Therapies: Novel treatment avenues from Cells, Bacteria, and extracellular sources
AAIantigen-antibody integratorAPRILa proliferating inducing ligandASPIREantigen self-presentation and immunosuppression re...
Fabrication and characterization of dissolving microneedles combining digital light processing and vacuum compression molding technique for the transdermal delivery of rivastigmine
Dissolving microneedles (MNs) are promising transdermal drug delivery systems that can effectively increase the absorption...
A novel long-acting phospholipid phase transition gel with progesterone effectively promoted uterine development
Infertility is a global issue, affecting approximately 48.5 million couples around the world [1,2]. Assisted reproductive ...
Intradermal delivery of teriflunomide loaded emulsomes using hollow microneedles for effective minimally invasive psoriasis management
Psoriasis is reported to be a widely spread autoimmune skin disease featuring high epidermal proliferation and increased d...
Peptide-based hydrogel co-assembled with antibody-drug for enhanced retinal cell uptake and attenuated experimental autoimmune uveitis
Blood-retinal barrier (BRB) destruction and inflammatory response are key contributors to the pathogenesis of various chro...
Leveraging engineered yeast small extracellular vesicles serve as multifunctional platforms for effectively loading methyl salicylate through the “esterase-responsive active loading” strategy
Due to the low bioavailability of many drugs, uneven distribution in the body, and easy metabolic inactivation, the use of...
Starch-Based scaffold produced by FDM 3D printing technique as Innovative and biosustainable wound dressing
Starch is a safe biopolymer, whose use for the production of scaffolds intended for deep wounds treatment is limited, due ...
Silica-based EGFR-degrading nano-PROTACs for efficient therapy of non-small cell lung cancer
Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related deaths worldwide with ...
Artificial gut Simulator. A scheme to predict intestinal and plasma concentration–time profiles of a weakly basic BCS-II drug, dipyridamole
Precipitation of a drug in the gastrointestinal (GI) tract, especially to a less soluble polymorph, can negatively impact ...
Vaginal formulation development: A strategy based on aptamer-guided liposome for human papillomavirus-induced lesions
Human Papillomavirus (HPV) is the main cause of cervical cancer, and formulations have been widely used to treat vaginal l...
Controlled release of deferiprone using iron-responsive nanoparticles integrated with dissolving microneedle for novel alternative treatments of β-thalassemia major
One global health problem that needs attention is ß-thalassemia major (ß-TM). ß-TM is a genetic disorder that occurs due t...
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