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Mesenchymal Stem/Stromal cells in solid tumor Microenvironment: Orchestrating NK cell remodeling and therapeutic insights
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Melatonin prevents glyphosate-induced hepatic lipid accumulation in roosters via activating Nrf2 pathway
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Zingerone attenuates concanavalin A-induced acute liver injury by restricting inflammatory responses
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Mechanistic study of quercetin in the treatment of hepatocellular carcinoma with diabetes via MEK/ERK pathway
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Pluripotent stem cell-derived CTLs targeting FGFR3-TACC3 fusion gene in osteosarcoma
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Efficacy of oxygen-ozone therapy against the pro-necrotic action of Loxosceles rufescens toxic bite
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Dysregulation and impaired anti-bacterial potential of mucosal-associated invariant T cells in autoimmune liver diseases
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Casting NETs on Psoriasis: The modulation of inflammatory feedback targeting IL-36/IL-36R axis
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Nicotinamide N-methyltransferase (NNMT): A key enzyme in cancer metabolism and therapeutic target
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Comparative study the alleviated effects of various oligosaccharides on colitis in mice
Comparative study the alleviated effects of various oligosaccharides on colitis in mice
The inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is characterized as a co...
GSDMD in regulated cell death: A novel therapeutic target for sepsis
GSDMD in regulated cell death: A novel therapeutic target for sepsis
In sepsis, invading pathogens can induce immune dysregulation in the body, resulting in a pathological syndrome characteri...
Decoding the role of the CCL2/CCR2 axis in Alzheimer’s disease and innovating therapeutic approaches: Keeping All options open
Decoding the role of the CCL2/CCR2 axis in Alzheimer’s disease and innovating therapeutic approaches: Keeping All options open
It is estimated that 50 million people worldwide are affected by dementia, which will grow to 152 million by 2050 [1]. Glo...
Unveiling YWHAH: A potential therapeutic target for overcoming CD8+ T cell exhaustion in colorectal cancer
Unveiling YWHAH: A potential therapeutic target for overcoming CD8+ T cell exhaustion in colorectal cancer
Colorectal cancer (CRC) is a significant global health challenge, with increasing rates of incidence and mortality. Despit...
scRNA + TCR-seq revealed the dual TCR pTh17 and Treg T cells involvement in autoimmune response in ankylosing spondylitis
scRNA + TCR-seq revealed the dual TCR pTh17 and Treg T cells involvement in autoimmune response in ankylosing spondylitis
The clonal selection theory that “a lymphocyte expresses only one receptor” [1]has been challenged and complemented by “du...
A novel insight into cancer therapy: Lipid metabolism in tumor-associated macrophages
A novel insight into cancer therapy: Lipid metabolism in tumor-associated macrophages
KeywordsLipid metabolismTumor-associated macrophagesTumor immune microenvironmentRadiotherapyChemotherapyImmunotherapyData...