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Sphingomyelin Inhibits Hydrolytic Activity of Heterodimeric PLA in Model Myelin Membranes: Pharmacological Relevance
Sphingomyelin Inhibits Hydrolytic Activity of Heterodimeric PLA in Model Myelin Membranes: Pharmacological Relevance
In this work, the heterodimeric phospholipase A2, HDP-2, from viper venom was investigated for its hydrolytic activity in ...
The Role of the Swollen State in Cell Proliferation
The Role of the Swollen State in Cell Proliferation
Cell swelling is known to be involved in various stages of the growth of plant cells and microorganisms but in mammalian c...
Effect of Triterpenoids Betulin and Betulinic Acid on Pulmonary Surfactant Membranes
Effect of Triterpenoids Betulin and Betulinic Acid on Pulmonary Surfactant Membranes
The purpose of this work is to examine how triterpenoids betulin (BE) and betulinic acid (BA) affect the thermotropic phas...
Interaction of an Oomycete Nep1-like Cytolysin with Natural and Plant Cell-Mimicking Membranes
Interaction of an Oomycete Nep1-like Cytolysin with Natural and Plant Cell-Mimicking Membranes
Plants are attacked by various pathogens that secrete a variety of effectors to damage host cells and facilitate infection...
Hetero-Oligomeric Protein Pores for Single-Molecule Sensing
Hetero-Oligomeric Protein Pores for Single-Molecule Sensing
Protein nanopores are emerging as versatile single-molecule sensors with broad applications in DNA and protein sequencing....
Cell-Free Systems and Their Importance in the Study of Membrane Proteins
Cell-Free Systems and Their Importance in the Study of Membrane Proteins
The Cell-Free Protein Synthesis (CFPS) is an innovative technique used to produce various proteins. It has several advanta...
Structural Dynamics of the Slide Helix of Inactive/Closed Conformation of KirBac1.1 in Micelles and Membranes: A Fluorescence Approach
Structural Dynamics of the Slide Helix of Inactive/Closed Conformation of KirBac1.1 in Micelles and Membranes: A Fluorescence Approach
Inward rectifying potassium (Kir) channels play a critical role in maintaining the resting membrane potential and cellular...
Pharmacodynamic characterization and evaluation of oxidative stress effects of digitoxigenin derivatives on HeLa cells
Pharmacodynamic characterization and evaluation of oxidative stress effects of digitoxigenin derivatives on HeLa cells
Cancer is a leading cause of death worldwide and its treatment is hampered by the lack of specificity and side effects of ...
Dengue Virus Fusion Peptide Promotes Hemifusion Formation by Disordering the Interfacial Region of the Membrane
Dengue Virus Fusion Peptide Promotes Hemifusion Formation by Disordering the Interfacial Region of the Membrane
Membrane fusion is the first step in the infection process of the enveloped viruses. Enveloped viruses fuse either at the ...
Computational Insights on the Assembly of the Dengue Virus Membrane–Capsid–RNA Complex
Computational Insights on the Assembly of the Dengue Virus Membrane–Capsid–RNA Complex
Dengue virus, an arbovirus from the genus Flavivirus in the family Flaviviridae, forms a nucleocapsid structure through in...
Gamma-Aminobutyric Acid Action on Membrane and Electrical Properties of Synaptosomes and Model Lipid Bilayers
Gamma-Aminobutyric Acid Action on Membrane and Electrical Properties of Synaptosomes and Model Lipid Bilayers
Dysfunction of the main inhibitory neurotransmitter gamma-aminobutyric acid (GABA) is the underlying reason behind many ne...
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein
Neurological diseases refer to pathological changes that occur in the brain, spinal cord, and peripheral nerves. Their eti...
Single-Molecule Insights into GPCR Conformational Landscapes
Single-Molecule Insights into GPCR Conformational Landscapes
Agyemang E, Gonneville AN, Tiruvadi-Krishnan S, Lamichhane R (2024) Exploring GPCR conformational dynamics using single-mo...
Metabolic Energy is Stored in a Homeostatic Trans-Membrane Water Barochemical Gradient
Metabolic Energy is Stored in a Homeostatic Trans-Membrane Water Barochemical Gradient
Trans-membrane water transport and co-transport is ubiquitous in cell biology. Integrated over all the c...
Correction: Single‑Molecule Insights into GPCR Conformational Landscapes
Correction: Single‑Molecule Insights into GPCR Conformational Landscapes
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Action of the Terminal Complement Pathway on Cell Membranes
Action of the Terminal Complement Pathway on Cell Membranes
The complement pathway is one of the most ancient elements of the host's innate response and includes a set of protein...
Cholesterol Concentration in Cell Membranes and its Impact on Receptor–Ligand Interaction: A Computational Study of ATP-Sensitive Potassium Channels and ATP Binding
Cholesterol Concentration in Cell Membranes and its Impact on Receptor–Ligand Interaction: A Computational Study of ATP-Sensitive Potassium Channels and ATP Binding
This work describes a computer study that looks at how different amounts of cholesterol (0%, 25%, and 50%) in cell membran...
Influence of physical activity practice on sexual function in men: a systematic review
Influence of physical activity practice on sexual function in men: a systematic review
While the health benefits of regular physical activity are well-documented, there is limited evidence specifically address...
Effect of oral contraceptive consumption timing on substrate metabolism, cognition, and exercise performance in females: a randomised controlled trial
Effect of oral contraceptive consumption timing on substrate metabolism, cognition, and exercise performance in females: a randomised controlled trial
The pharmacokinetic profile of oral contraceptives (OCs) results in an acute, transient increase in circulating synthetic ...
The effect of hypohydration before and different rehydration strategies after severe intensity exercise on post-exercise hypotension in men
The effect of hypohydration before and different rehydration strategies after severe intensity exercise on post-exercise hypotension in men
We examined the effect of 12 h of fluid deprivation before, and three different rehydration strategies (none, fix...
Enhanced joint energy transfer potential by the biarticular gastrocnemii muscles during perturbed walking
Enhanced joint energy transfer potential by the biarticular gastrocnemii muscles during perturbed walking
Our objective was to explore how the potential for energy transfer between the ankle and knee joint via the biarticular ga...
24 h severe fluid restriction increases a biomarker of renal injury in healthy males
24 h severe fluid restriction increases a biomarker of renal injury in healthy males
Exercise-induced hypohydration exacerbates biomarkers of renal injury, but studies isolating the effects of hypohydration ...
Hormonal and metabolic responses across phases of combined oral contraceptive use and menstrual cycle in young elite female athletes
Hormonal and metabolic responses across phases of combined oral contraceptive use and menstrual cycle in young elite female athletes
Despite the significant number of female athletes using combined oral contraceptives (COCs), there is scant literature on ...
The effects of chronic stretch training on musculoskeletal pain
The effects of chronic stretch training on musculoskeletal pain
One of the primary mechanisms for the increase in range of motion following stretching is an increase in pain/stretch tole...
Cardiovascular and cerebral hemodynamics during static and dynamic breath-holding
Cardiovascular and cerebral hemodynamics during static and dynamic breath-holding
The study investigated the changes in cardiovascular and cerebral hemodynamics elicited by the diving response during stat...
Eccentric training effects on hamstring muscles in oral contraceptive users and naturally menstruating women
Eccentric training effects on hamstring muscles in oral contraceptive users and naturally menstruating women
This study evaluated the effects of eccentric resistance training on hamstring muscles properties in women using oral cont...
The accuracy of fixed intensity anchors to estimate lactate thresholds in recreational runners
The accuracy of fixed intensity anchors to estimate lactate thresholds in recreational runners
Endurance exercise intensities can be categorized into moderate, heavy, and severe domains based on physiological response...
Lactic acidosis: implications for human exercise performance
Lactic acidosis: implications for human exercise performance
During high-intensity exercise a lactic-acidosis occurs with raised myoplasmic and plasma concentrations of lactate−...
Evaluating the impact of coenzyme Q10 and high-intensity interval training on lactate threshold and Plasma blood gases in rats: a randomized controlled trial
Evaluating the impact of coenzyme Q10 and high-intensity interval training on lactate threshold and Plasma blood gases in rats: a randomized controlled trial
Coenzyme Q10 (Q10) is a mitochondrial coenzyme that facilitates ATP production via oxidative phosphorylation. This study h...
Blood lactate accumulation during maximal cycling sprints and its relationship to sprint performance characteristics
Blood lactate accumulation during maximal cycling sprints and its relationship to sprint performance characteristics
Blood lactate accumulation (ΔBLC) during maximal short-term exercise is a crucial indicator of peak glycolytic activa...
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