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Correlation Between Antimicrobial Structural Classes and Membrane Partitioning: Role of Emerging Lipid Packing Defects
Correlation Between Antimicrobial Structural Classes and Membrane Partitioning: Role of Emerging Lipid Packing Defects
In this study, a combination of bioinformatics and molecular dynamics simulations is employed to investigate the partition...
A Critical Review of Short Antimicrobial Peptides from Scorpion Venoms, Their Physicochemical Attributes, and Potential for the Development of New Drugs
A Critical Review of Short Antimicrobial Peptides from Scorpion Venoms, Their Physicochemical Attributes, and Potential for the Development of New Drugs
Scorpion venoms have proven to be excellent sources of antimicrobial agents. However, although many of them have been func...
N-Glycosylation Deficiency in Transgene α7 nAChR and RIC3 Expressing CHO Cells Without NACHO
N-Glycosylation Deficiency in Transgene α7 nAChR and RIC3 Expressing CHO Cells Without NACHO
The human neuronal nicotinic acetylcholine receptor α7 (nAChR) is an important target implicated in diseases like Alz...
Sperm-Specific CatSper is Not Conserved in All Vertebrates and May Not be the Only Progesterone-Responsive Ion Channel Present in Sperm
Sperm-Specific CatSper is Not Conserved in All Vertebrates and May Not be the Only Progesterone-Responsive Ion Channel Present in Sperm
Progesterone (P4) acts as a key conserved signalling molecule in vertebrate reproduction. P4 is especially important for m...
Beyond Hormones: Investigating the Impact of Progesterone Receptor Membrane Component 1 in Lung Adenocarcinoma
Beyond Hormones: Investigating the Impact of Progesterone Receptor Membrane Component 1 in Lung Adenocarcinoma
Progesterone Receptor Membrane Component 1 (PGRMC1) is a candidate oncogene with a prominent involvement in the pathogenes...
Feasibility Study for the Use of Gene Electrotransfer and Cell Electrofusion as a Single-Step Technique for the Generation of Activated Cancer Cell Vaccines
Feasibility Study for the Use of Gene Electrotransfer and Cell Electrofusion as a Single-Step Technique for the Generation of Activated Cancer Cell Vaccines
Cell-based therapies hold great potential for cancer immunotherapy. This approach is based on manipulation of dendritic ce...
A Model for Reversible Electroporation to Deliver Drugs into Diseased Tissues
A Model for Reversible Electroporation to Deliver Drugs into Diseased Tissues
Drug delivery through electroporation could be highly beneficial for the treatment of different types of diseased tissues ...
Residues of TRPM8 at the Lipid-Water-Interface have Coevolved with Cholesterol Interaction and are Relevant for Diverse Health Disorders
Residues of TRPM8 at the Lipid-Water-Interface have Coevolved with Cholesterol Interaction and are Relevant for Diverse Health Disorders
TRPM8 is a non-selective cation channel that is expressed in several tissues and cells and also has a unique property to b...
Evolution of Bioelectric Membrane Potentials: Implications in Cancer Pathogenesis and Therapeutic Strategies
Evolution of Bioelectric Membrane Potentials: Implications in Cancer Pathogenesis and Therapeutic Strategies
Electrophysiology typically deals with the electrical properties of excitable cells like neurons and muscles. However, all...
Early Events in β2AR Dimer Dynamics Mediated by Activation-Related Microswitches
Early Events in β2AR Dimer Dynamics Mediated by Activation-Related Microswitches
G-Protein-Coupled Receptors (GPCRs) make up around 3–4% of the human genome and are the targets of one-third of FDA-...
Enhancing Anti-Cancer Immune Response by Acidosis-Sensitive Nanobody Display
Enhancing Anti-Cancer Immune Response by Acidosis-Sensitive Nanobody Display
One of the main challenges with many cancer immunotherapies is that biomarkers are needed for targeting. These biomarkers ...
Voltage Gated Ion Channels and Sleep
Voltage Gated Ion Channels and Sleep
Ion channels are integral components of the nervous system, playing a pivotal role in shaping membrane potential, neuronal...
Postsynaptic Density Proteins and Their Role in the Trafficking of Group I Metabotropic Glutamate Receptors
Postsynaptic Density Proteins and Their Role in the Trafficking of Group I Metabotropic Glutamate Receptors
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system that regulates multiple differe...
Is Travel Associated With Match Performance in Elite North American Professional Soccer? An Exploratory Study
Is Travel Associated With Match Performance in Elite North American Professional Soccer? An Exploratory Study
Purpose: Travel fatigue impacts cognitive and physiologic systems, but its association with elite soccer match performance...
Self-Reported Menstrual Health, Symptomatology, and Perceived Effects of the Menstrual Cycle for Elite Junior and Senior Football Players
Self-Reported Menstrual Health, Symptomatology, and Perceived Effects of the Menstrual Cycle for Elite Junior and Senior Football Players
Purpose: To describe the self-reported menstrual health, symptomatology, and perceived effects of the menstrual cycle on a...
Running Shoes of the Postmodern Footwear Era: A Narrative Overview of Advanced Footwear Technology
Running Shoes of the Postmodern Footwear Era: A Narrative Overview of Advanced Footwear Technology
The modern era of running shoes began in the 1960s with the introduction of simple polymer midsole foams, and it ended in ...
Stress Drives Soccer Athletes’ Wellness and Movement: Using Convergent Cross-Mapping to Identify Causal Relationships in a Dynamic Environment
Stress Drives Soccer Athletes’ Wellness and Movement: Using Convergent Cross-Mapping to Identify Causal Relationships in a Dynamic Environment
Purpose: Prediction of athlete wellness is difficult—or, many sports-medicine practitioners and scientists would argue, im...
Mental Fatigue in Sport—From Impaired Performance to Increased Injury Risk
Mental Fatigue in Sport—From Impaired Performance to Increased Injury Risk
The literature describing the effects of mental fatigue (MF) has grown tremendously. This is accompanied by identification...
Training for Elite Team-Pursuit Track Cyclists—Part II: A Comparison of Preparation Phases in Consecutive World-Record-Breaking Seasons
Training for Elite Team-Pursuit Track Cyclists—Part II: A Comparison of Preparation Phases in Consecutive World-Record-Breaking Seasons
Purpose: To compare the training characteristics of an elite team pursuit cycling squad in the 3-month preparation phases ...
Physiological and Performance Adaptations to Varying Rest Distributions During Short Sprint Interval Training Trials in Female Volleyball Players: A Comparative Analysis of Interindividual Variability
Physiological and Performance Adaptations to Varying Rest Distributions During Short Sprint Interval Training Trials in Female Volleyball Players: A Comparative Analysis of Interindividual Variability
Purpose: This study aimed to examine the impact of different rest periods between short sprint interval training (SSIT) tr...
Training for Elite Team-Pursuit Track Cyclists—Part I: A Profile of General Training Characteristics
Training for Elite Team-Pursuit Track Cyclists—Part I: A Profile of General Training Characteristics
Purpose: To profile the training characteristics of an elite team pursuit cycling squad and assess variations in training ...
External Training Loads and Soft-Tissue Injury Occurrence During Congested Versus Noncongested Periods in Football
External Training Loads and Soft-Tissue Injury Occurrence During Congested Versus Noncongested Periods in Football
Objective: To analyze the influence of congested and noncongested fixture periods during 2 seasons in a professional male ...
Chronobiological Insights in Plyometric Jump Training: Optimizing Sport-Performance Adaptations for Volleyball Players
Chronobiological Insights in Plyometric Jump Training: Optimizing Sport-Performance Adaptations for Volleyball Players
Purpose: The objective of this study was to investigate the effects of morning versus evening plyometric training (PT) on ...
The Evolvement of Session Design From Junior Age to Senior Peak Performance in World-Class Cross-Country Skiers
The Evolvement of Session Design From Junior Age to Senior Peak Performance in World-Class Cross-Country Skiers
Purpose: To compare designs of training sessions applied by world-class cross-country skiers during their most successful ...
The Determinants of Maximal Speed Adaptation During Preseason in Subelite Female Australian Rules Footballers
The Determinants of Maximal Speed Adaptation During Preseason in Subelite Female Australian Rules Footballers
Purpose: Maximal speed is an important physical-fitness attribute for female Australian footballers. The effects of sprint...
Effects of 6-Week Weighted-Jump-Squat Training With and Without Eccentric Load Reduction on Explosive Performance
Effects of 6-Week Weighted-Jump-Squat Training With and Without Eccentric Load Reduction on Explosive Performance
Purpose: To compare the effects of 6-week barbell weighted-jump-squat (WJS) training with and without eccentric load reduc...
Effects of Velocity Loss During Bench-Press Training With Light Relative Loads
Effects of Velocity Loss During Bench-Press Training With Light Relative Loads
Purpose: This study explored the effects of 4 bench-press (BP) training programs with different velocity-loss (VL) thresho...
No Impact of Anthropometric and Fitness Factors on Speed–Agility in Young Soccer Players: Is It a Cognitive Influence?
No Impact of Anthropometric and Fitness Factors on Speed–Agility in Young Soccer Players: Is It a Cognitive Influence?
Purpose: Agility in young soccer players has long been associated with physical attributes like strength, speed, and power...
Gaelic Games Players’ and Practitioners’ Perceptions of Recovery Strategies
Gaelic Games Players’ and Practitioners’ Perceptions of Recovery Strategies
Purpose: This study both investigated and compared Gaelic games players’ and practitioners’ perceptions of the importance ...
Transcranial Direct-Current Stimulation Over the Primary Motor Cortex and Cerebellum Improves Balance and Shooting Accuracy in Elite Ice Hockey Players
Transcranial Direct-Current Stimulation Over the Primary Motor Cortex and Cerebellum Improves Balance and Shooting Accuracy in Elite Ice Hockey Players
Purpose: To investigate the effects of transcranial direct-current stimulation (tDCS) applied over the primary motor corte...
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