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Magnetic nanoparticles and their hybrid biomaterials for drug delivery and theranostic applications in cardiovascular diseases
Magnetic nanoparticles and their hybrid biomaterials for drug delivery and theranostic applications in cardiovascular diseases
Cardiovascular diseases (CVDs) remain a significant global health concern, as indicated by numerous studies [1]. Worldwide...
αvβ3 integrin targeting RGD peptide-based nanoparticles as an effective strategy for selective drug delivery to tumor microenvironment
αvβ3 integrin targeting RGD peptide-based nanoparticles as an effective strategy for selective drug delivery to tumor microenvironment
Cancer is the second greatest cause of mortality worldwide and a serious health concern and is characterized by the uncont...
Harnessing silk fibroin microparticles for metformin delivery: A novel approach to treating corneal neovascularization
Harnessing silk fibroin microparticles for metformin delivery: A novel approach to treating corneal neovascularization
In healty condition, the cornea is a translucent, avascular connective tissue. However, a number of inflammatory, viral, a...
Isoliquiritigenin-infused electrospun nanofiber inhibits breast cancer proliferation and invasion through downregulation of PI3K/Akt/mTOR and MMP2/9 pathways
Isoliquiritigenin-infused electrospun nanofiber inhibits breast cancer proliferation and invasion through downregulation of PI3K/Akt/mTOR and MMP2/9 pathways
Breast cancer (BC) is the most common cancer among women worldwide. Despite the use of adjuvant strategies such as radioth...
Vascular normalization with pegylated emulsion of SU5416 enhances anti-tumor effect of liposomal paclitaxel in 4T1 breast cancer-bearing mice: Analysis of intratumoral vessels and microenvironment
Vascular normalization with pegylated emulsion of SU5416 enhances anti-tumor effect of liposomal paclitaxel in 4T1 breast cancer-bearing mice: Analysis of intratumoral vessels and microenvironment
Cancer cells induce angiogenesis for themselves to obtain oxygen and nutrients for the growth and metastasis of solid tumo...
Quercetin-loaded transliposomal gel for effective management of skin cancer: In vitro and cell line efficacy studies
Quercetin-loaded transliposomal gel for effective management of skin cancer: In vitro and cell line efficacy studies
Skin carcinoma is a highly perilous form of cancer that was initially documented by Laennec in 1804 for melanoma, Jacob in...
Preparation and characterization of injectable in-situ forming gel based on lipid liquid crystal for one month delivery of aripiprazole: In-vitro and in-vivo evaluations in rats
Preparation and characterization of injectable in-situ forming gel based on lipid liquid crystal for one month delivery of aripiprazole: In-vitro and in-vivo evaluations in rats
Aripiprazole, marketed under the brand name Abilify®, belongs to the class of atypical antipsychotics. It functions as a p...
Enhancement of transdermal vaccination using electrothermal active interfaces
Enhancement of transdermal vaccination using electrothermal active interfaces
Vaccination is a vital healthcare strategy for preventing and controlling infectious diseases in humans and animals [1,2]....
Salvia coccinea Buc'hoz ex Etl. Leaf extract mediated synthesis of zinc oxide nanoparticles: Assessment of antimicrobial, antioxidant and anticancer activity
Salvia coccinea Buc'hoz ex Etl. Leaf extract mediated synthesis of zinc oxide nanoparticles: Assessment of antimicrobial, antioxidant and anticancer activity
Medicinal plants have a long history of usage in traditional medicine to ancient times. These plants have been utilized in...
Development and in vitro evaluation of liposomal carnosine for dermatological and cosmeceutical applications
Development and in vitro evaluation of liposomal carnosine for dermatological and cosmeceutical applications
Carnosine (β-alanyl- l-histidine) is a water-soluble dipeptide characterized by three ionizable groups [1,2]. The molecule...
Development, optimization, in-vitro, and in-vivo evaluation of chitosan-inlayed nano-spanlastics encompassing lercanidipine HCl for enhancement of bioavailability
Development, optimization, in-vitro, and in-vivo evaluation of chitosan-inlayed nano-spanlastics encompassing lercanidipine HCl for enhancement of bioavailability
Oral drug administration is regarded as the most popular, convenient, and widespread mode of administration. It has variou...
Synthesis of naringenin-betaine cocrystal by gas antisolvent technique and cell models for in vitro permeation studies
Synthesis of naringenin-betaine cocrystal by gas antisolvent technique and cell models for in vitro permeation studies
Naringenin (NRG, C15H12O5, 4′,5,7- trihydroxyflavanone, molecular weight 272.25 g/mol, Scheme 1) is a naturally occurring ...
Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence
Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence
Glioblastoma (GB) is the most common and aggressive brain tumor. The treatment for newly diagnosed glioblastoma is surgica...
Development of ginger-derived extracellular vesicles thermosensitive gel for UVA-induced photodamage of skin
Development of ginger-derived extracellular vesicles thermosensitive gel for UVA-induced photodamage of skin
Extracellular vesicles (EVs) are lipid bilayer vesicles that are secreted from almost all cell types, serve as “messengers...
Enhancement of in-vivo cellular uptake of Coenzyme Q10 using saponin derivatives in rTALAP transgenic mice model
Enhancement of in-vivo cellular uptake of Coenzyme Q10 using saponin derivatives in rTALAP transgenic mice model
Pancreatic cancer, a prominent cause of cancer-related deaths in both men and women, ranks among the top cancers associate...
Preparation of antibody-loaded protein microbeads for pulmonary delivery via Shirasu porous glass membrane emulsification and freeze drying
Preparation of antibody-loaded protein microbeads for pulmonary delivery via Shirasu porous glass membrane emulsification and freeze drying
Most therapeutic proteins are vulnerable to physicochemical degradation as exposed to pH change and digestive enzymes, and...
Evaluation of ZnO nanoparticles from ‘Monsooned Malabar Robusta Coffee’ husk as a potential antioxidant and biocidal candidate: A sustainable valorization approach
Evaluation of ZnO nanoparticles from ‘Monsooned Malabar Robusta Coffee’ husk as a potential antioxidant and biocidal candidate: A sustainable valorization approach
In recent times, agricultural production has skyrocketed due to the impact of the green revolution and technological advan...
Pharmacodynamic study: Astragaloside IV/chitosan/polylactic acid composite electrospinning scaffold for wound healing in diabetic rats
Pharmacodynamic study: Astragaloside IV/chitosan/polylactic acid composite electrospinning scaffold for wound healing in diabetic rats
With the improvement of living standards, the changes in diet structure, and the aging of the population, the prevalence o...
Evaluation of preclinical efficacy of apremilast-loaded liquid crystalline nanoparticulate gel in amelioration of atopic dermatitis
Evaluation of preclinical efficacy of apremilast-loaded liquid crystalline nanoparticulate gel in amelioration of atopic dermatitis
Phosphodiesterase (PDE)-4 is an enzyme responsible for the activity of various inflammatory cytokines. The increased level...
BBD assisted in-situ nanoliposomes of esculin hydrate via intranasal delivery for the amelioration of Parkinson's disease
BBD assisted in-situ nanoliposomes of esculin hydrate via intranasal delivery for the amelioration of Parkinson's disease
Parkinson's disease (PD) is a rapid neurodegenerative disorder of central nervous system (CNS caused by the reduction in l...
An overview of nanofibers and microfibers for improved oral delivery of medicines: Challenges and advances
An overview of nanofibers and microfibers for improved oral delivery of medicines: Challenges and advances
Microfibers and nanofibers are solid polymer-based carriers that exhibit particle sizes ranging from micrometers to nanome...
Curcumin-loaded chitosan-protamine nanoparticles: A promising approach to ameliorate nicotine-induced reproductive disorders in male rats
Curcumin-loaded chitosan-protamine nanoparticles: A promising approach to ameliorate nicotine-induced reproductive disorders in male rats
The tobacco epidemic represents one of the most significant threats to public health globally, resulting in the death of o...
Evaluation of anticancer effect of micelle-encapsulated doxorubicin using gamma-distributed delay model
Evaluation of anticancer effect of micelle-encapsulated doxorubicin using gamma-distributed delay model
Functional nanoparticles incorporating active-targeting systems, such as those targeting folic acid receptor and αVβ3 inte...
Formulation development and evaluation of fluvastatin loaded transethosomes: Characterization, stability, in vitro dermal penetration, cytotoxicity and antipsoriatic activity studies
Formulation development and evaluation of fluvastatin loaded transethosomes: Characterization, stability, in vitro dermal penetration, cytotoxicity and antipsoriatic activity studies
Psoriasis is one of the most common immune-mediated chronic inflammatory diseases, presenting a significant public health ...
Development, optimization and in-vivo pharmacokinetic evaluation of flubiprofen nanocrystal tablets for efficient chronotherapy against rheumatoid arthritis
Development, optimization and in-vivo pharmacokinetic evaluation of flubiprofen nanocrystal tablets for efficient chronotherapy against rheumatoid arthritis
The daily variations in the environment brought on by the rotation of the globe (for example, the amount of sunshine) are ...
Folic acid-conjugated cancer drug curcumin-loaded albumin nanoparticles: Investigation of curcumin release kinetics
Folic acid-conjugated cancer drug curcumin-loaded albumin nanoparticles: Investigation of curcumin release kinetics
Cancer still remains one of the leading causes of morbidity worldwide despite great efforts and advancements in cancer pre...
Development and characterization of inhaled nintedanib-loaded PLGA nanoparticles using scalable high-pressure homogenization technique
Development and characterization of inhaled nintedanib-loaded PLGA nanoparticles using scalable high-pressure homogenization technique
Nint is a potent small molecule that inhibits tyrosine kinases receptors (RTKs), including receptors of fibroblast growth ...
A novel quercetin-loaded NiFe2O4@Liposomes hybrid biocompatible as a potential chemotherapy/hyperthermia agent and cytotoxic effects on breast cancer cells
A novel quercetin-loaded NiFe2O4@Liposomes hybrid biocompatible as a potential chemotherapy/hyperthermia agent and cytotoxic effects on breast cancer cells
As a significant threat to public health, breast cancer is the most common tumor in women, with approximately 2.3 million ...
Macrophage membrane-coated self-assembled curcumin nanoparticle missile for the treatment of colorectal cancer
Macrophage membrane-coated self-assembled curcumin nanoparticle missile for the treatment of colorectal cancer
Cancer is a major public health issue worldwide. Despite the numerous treatment methods available, the demand for effectiv...
Co-amorphous mixture of erlotinib hydrochloride and gallic acid for enhanced antitumor effects
Co-amorphous mixture of erlotinib hydrochloride and gallic acid for enhanced antitumor effects
Despite great effort made by our human beings, cancers still seriously threaten our health and life [1]. To avoid the seve...
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