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Site-specific bioorthogonal regulation of bone morphogenetic protein 2 expression for effective bone regeneration
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Injectable dual thermoreversible hydrogel for sustained intramuscular drug delivery
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Liver-targeting chimeras as a potential modality for the treatment of liver diseases
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Fluorogenic RNA-based biomaterials for imaging and tracking the cargo of extracellular vesicles
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Stealth mRNA nanovaccines to control lymph node trafficking
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Biocompatible polymer-based micro/nanorobots for theranostic translational applications
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The advance of ultrasound-enabled diagnostics and therapeutics
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Design of probiotic delivery systems and their therapeutic effects on targeted tissues
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Regulation of mechanical properties of microcapsules and their applications
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Optimization of a pendant-shaped PEGylated linker for antibody-drug conjugates
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Brain-tumor-seeking and serpin-inhibiting outer membrane vesicles restore plasmin-mediated attacks against brain metastases
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Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria
Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria
Although various types of mRNA-based vaccines have been explored, the optimal conditions for induction of both humoral and...
UiO-66(Zr) as drug delivery system for non-steroidal anti-inflammatory drugs
UiO-66(Zr) as drug delivery system for non-steroidal anti-inflammatory drugs
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed drugs for pain and inflammatory treatment ar...
Cell selective BCL-2 inhibition enabled by lipid nanoparticles alleviates lung fibrosis
Cell selective BCL-2 inhibition enabled by lipid nanoparticles alleviates lung fibrosis
American Lung Association has revealed the incidence and prevalence of almost 50,000 new cases of Idiopathic pulmonary fib...
Long-term combined blockade of CXCR4 and PD-L1 with in vivo reassembly for intensive tumor interference
Long-term combined blockade of CXCR4 and PD-L1 with in vivo reassembly for intensive tumor interference
Cancer immunotherapy harnessed an individual's immune system to detect and destroy tumor cells. [[1], [2], [3]] The bloomi...
Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
A critical parameter during the development of protein therapeutics is to endow them with suitable pharmacokinetic and pha...
Multidimensional opioid abuse deterrence using a nanoparticle-polymer hybrid formulation
Multidimensional opioid abuse deterrence using a nanoparticle-polymer hybrid formulation
Driven by increasing opioid addiction, drug overdose has become a leading cause of death in the United States [1]. The dis...