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Cost Effectiveness of Sequencing Vedolizumab as First-Line Biologic in Ulcerative Colitis and Crohn's Disease in Canada: An Analysis Using Real-World Evidence from the EVOLVE Study
Cost Effectiveness of Sequencing Vedolizumab as First-Line Biologic in Ulcerative Colitis and Crohn's Disease in Canada: An Analysis Using Real-World Evidence from the EVOLVE Study
Vedolizumab is a gut‐selective anti‐lymphocyte trafficking biologic indicated for the treatment of adult patie...
Integrating Multi-Cancer Early Detection (MCED) Tests with Standard Cancer Screening: System Dynamics Model Development and Feasibility Testing
Integrating Multi-Cancer Early Detection (MCED) Tests with Standard Cancer Screening: System Dynamics Model Development and Feasibility Testing
Cancer screening plays a critical role in early disease detection and improving outcomes. In Australia, established screen...
Health Economic Evaluation of Antimicrobial Stewardship, Procalcitonin Testing, and Rapid Blood Culture Identification in Sepsis Care: A 90-Day Model-Based, Cost-Utility Analysis
Health Economic Evaluation of Antimicrobial Stewardship, Procalcitonin Testing, and Rapid Blood Culture Identification in Sepsis Care: A 90-Day Model-Based, Cost-Utility Analysis
We evaluated the cost-effectiveness of a bundled intervention including an antimicrobial stewardship program (ASP), procal...
Clinical Complications and Healthcare Resource Utilization Associated with Conventional Management of Sickle Cell Disease with Recurrent Vaso-occlusive Crises and Transfusion-Dependent β-Thalassemia in Germany
Clinical Complications and Healthcare Resource Utilization Associated with Conventional Management of Sickle Cell Disease with Recurrent Vaso-occlusive Crises and Transfusion-Dependent β-Thalassemia in Germany
The purpose of this study was to describe clinical complications and healthcare resource utilization (HCRU) among patients...
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Obesity is a global health issue with significant economic implications for health systems. Pharmacotherapy, including sem...
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
The authorization of new therapeutic indications for drugs already reimbursed by the Italian National Health Service (NHS)...
Cost-Utility Analysis of LifeVest® in Post-Myocardial Infarction Patients at Risk of Sudden Cardiac Death in England
Cost-Utility Analysis of LifeVest® in Post-Myocardial Infarction Patients at Risk of Sudden Cardiac Death in England
Patients with a left ventricular ejection fraction ≤ 35% are at increased risk of sudden cardiac death (SCD) within ...
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
Disparities in access to oncology medicines in European Union (EU) member states can impact patient outcomes profoundly, w...
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Immune checkpoint inhibitor (ICI)-containing treatment is currently prescribed as first-line treatment for all patients wi...
COVID-19 Vaccine Preferences in China: A Comparison of Discrete Choice Experiment and Profile Case Best–Worst Scaling
COVID-19 Vaccine Preferences in China: A Comparison of Discrete Choice Experiment and Profile Case Best–Worst Scaling
Little is known about the diversity of residents' preferences for COVID-19 vaccines during the time when COVID-19 mana...
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher inc...
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
Given that Korea lacks measures to promote cost-effective prescribing, this study investigated the efficiency of prescribe...
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Many decision-makers have emphasized the importance of leveraging patient experience data to measure unmet need. However, ...
Cost Effectiveness of Left Ventricular Assist Devices (LVADs) as Destination Therapy: A Systematic Review
Cost Effectiveness of Left Ventricular Assist Devices (LVADs) as Destination Therapy: A Systematic Review
Left ventricular assist devices (LVADs) can extend life and improve quality of life among advanced heart failure patients ...
Clinicians’ Preferences for Sphingosine-1-Phosphate Receptor Modulators in Multiple Sclerosis Based on Clinical Management Considerations: A Choice Experiment
Clinicians’ Preferences for Sphingosine-1-Phosphate Receptor Modulators in Multiple Sclerosis Based on Clinical Management Considerations: A Choice Experiment
Four sphingosine-1-phosphate receptor (S1PR) modulators are currently available in the USA for treating relapsing forms of...
ENTIMOS: Decision Support Tool Highlights Potential Impact of Non-intravenous Therapies for Multiple Sclerosis on Patient Care via Clinical Scenario Simulation
ENTIMOS: Decision Support Tool Highlights Potential Impact of Non-intravenous Therapies for Multiple Sclerosis on Patient Care via Clinical Scenario Simulation
Administration of intravenous (IV), high-efficacy treatments (HETs) for the treatment of multiple sclerosis (MS) poses a h...
A Cost Evaluation of COVID-19 Remote Home Monitoring Services in England
A Cost Evaluation of COVID-19 Remote Home Monitoring Services in England
Remote home monitoring services emerged as critical components of health care delivery from NHS England during the COVID-1...
Cost-Effectiveness of Vedolizumab as a First-Line Advanced Therapy Versus Adalimumab Treatment Sequences for Ulcerative Colitis in Italy
Cost-Effectiveness of Vedolizumab as a First-Line Advanced Therapy Versus Adalimumab Treatment Sequences for Ulcerative Colitis in Italy
Today, there are many treatment options available for the management of ulcerative colitis, creating challenges in selecti...
Cost and Quality of Life of Disability Progression in Multiple Sclerosis Beyond EDSS: Impact of Cognition, Fatigue, and Limb Impairment
Cost and Quality of Life of Disability Progression in Multiple Sclerosis Beyond EDSS: Impact of Cognition, Fatigue, and Limb Impairment
Understanding the socioeconomic burden of multiple sclerosis (MS) is essential to inform policymakers and payers. Real-wor...
Psychometric Properties of the EQ-5D-5L in Patients with Alopecia Areata
Psychometric Properties of the EQ-5D-5L in Patients with Alopecia Areata
For many decision makers in Health Technology Assessment the EQ-5D-5L is the standard measure of health-related quality of...
Using a Patient-Centered Multicriteria Decision Analysis to Assess the Value of Multiple Sclerosis Treatments in the US: A Study Protocol
Using a Patient-Centered Multicriteria Decision Analysis to Assess the Value of Multiple Sclerosis Treatments in the US: A Study Protocol
The engagement of patients and family caregivers in value assessment is pivotal since they provide valuable contributions ...
A Cost-Effectiveness Analysis of Adjuvant Nivolumab for Patients with Resected Esophageal Cancer or Gastroesophageal Junction Cancer in France
A Cost-Effectiveness Analysis of Adjuvant Nivolumab for Patients with Resected Esophageal Cancer or Gastroesophageal Junction Cancer in France
Esophageal and gastroesophageal junction cancer (EC/GEJC) is a poor prognosis disease with a high risk of recurrence even ...
Impact of Value-Driven Healthcare Strategies for Biosimilar Adoption: The Singapore Story
Impact of Value-Driven Healthcare Strategies for Biosimilar Adoption: The Singapore Story
Healthcare sustainability is a global challenge. Various value-driven healthcare strategies have been implemented by Singa...
Budget Impact Analysis of Olaparib for the Management of Patients with Homologous Recombination Repair (HRR)-Mutated Castration-Resistant Metastatic Prostate Cancer in Argentina
Budget Impact Analysis of Olaparib for the Management of Patients with Homologous Recombination Repair (HRR)-Mutated Castration-Resistant Metastatic Prostate Cancer in Argentina
The aim of this study was to perform a budget impact analysis (BIA) of introducing olaparib treatment for adult patients w...
Modeling First-Line Daratumumab Use for Newly Diagnosed, Transplant-Ineligible, Multiple Myeloma: A Cost-Effectiveness and Risk Analysis for Healthcare Payers
Modeling First-Line Daratumumab Use for Newly Diagnosed, Transplant-Ineligible, Multiple Myeloma: A Cost-Effectiveness and Risk Analysis for Healthcare Payers
This study aimed to assess the cost-effectiveness of two regimens regarded as the standard of care for the treatment of ne...
Healthcare Resource Utilization and Associated Costs During the First 5 Years After Diagnosis and at the End of Life: A Nationwide Cohort Study of Patients with Multiple Myeloma in Finland
Healthcare Resource Utilization and Associated Costs During the First 5 Years After Diagnosis and at the End of Life: A Nationwide Cohort Study of Patients with Multiple Myeloma in Finland
The burden associated with the treatment of patients with multiple myeloma (MM) is expected to increase due to the aging p...
Artificial-Intelligence Cloud-Based Platform to Support Shared Decision-Making in the Locoregional Treatment of Breast Cancer: Protocol for a Multidimensional Evaluation Embedded in the CINDERELLA Clinical Trial
Artificial-Intelligence Cloud-Based Platform to Support Shared Decision-Making in the Locoregional Treatment of Breast Cancer: Protocol for a Multidimensional Evaluation Embedded in the CINDERELLA Clinical Trial
Shared decision-making (SDM) plays a crucial role in breast cancer care by empowering patients and reducing decision regre...
Publisher Correction: Health Technology Assessment Reports for Non-Oncology Medications in Canada from 2018 to 2022: Methodological Critiques on Manufacturers’ Submissions and a Comparison Between Manufacturer and Canadian Agency for Drugs and Technologies in Health (CADTH) Analyses
Publisher Correction: Health Technology Assessment Reports for Non-Oncology Medications in Canada from 2018 to 2022: Methodological Critiques on Manufacturers’ Submissions and a Comparison Between Manufacturer and Canadian Agency for Drugs and Technologies in Health (CADTH) Analyses
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International ...
Estimation of Health State Utility Values for Immunoglobulin A Nephropathy: A Time Trade-Off Analysis
Estimation of Health State Utility Values for Immunoglobulin A Nephropathy: A Time Trade-Off Analysis
Immunoglobulin A nephropathy (IgAN) is a rare progressive disease that can lead to kidney failure. The current study aimed...
Cost-Utility and Budget Impact Analysis of Adding SGLT-2 Inhibitors to Standard Treatment in Type 2 Diabetes Patients with Heart Failure: Utilizing National Database Insights from Thailand
Cost-Utility and Budget Impact Analysis of Adding SGLT-2 Inhibitors to Standard Treatment in Type 2 Diabetes Patients with Heart Failure: Utilizing National Database Insights from Thailand
Heart failure (HF) in type 2 diabetes (T2D) patients poses a significant clinical and financial burden. While sodium-gluco...
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