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Cost-Effectiveness Analyses of Adolescent- and Young-Adult-Focused HIV Interventions Incorporating HIV Transmission: a Scoping Review of Modeling Methods and Proposed Guidance
Cost-Effectiveness Analyses of Adolescent- and Young-Adult-Focused HIV Interventions Incorporating HIV Transmission: a Scoping Review of Modeling Methods and Proposed Guidance
Adolescents and young adults (AYA) are disproportionately affected by human immunodeficiency virus (HIV) globally, with hi...
Exploratory Cost-Effectiveness of a Novel Bioprosthetic Valve for Surgical Aortic Valve Replacement in Spain
Exploratory Cost-Effectiveness of a Novel Bioprosthetic Valve for Surgical Aortic Valve Replacement in Spain
Limited information is available regarding the impact of valve choice for patients with aortic stenosis (AS) undergoing su...
Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil
Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil
Decision analytical models are typically included in health economic evaluations to represent clinical pathways and enable...
An Enhanced Retention Strategy to Prevent the Vertical Transmission of HIV in Uganda: A Budget Impact Analysis
An Enhanced Retention Strategy to Prevent the Vertical Transmission of HIV in Uganda: A Budget Impact Analysis
Novel retention strategies have the potential to reduce vertical transmission of HIV and improve patient outcomes for wome...
Real-World Analysis of Healthcare Utilization, Treatment Patterns, and Economic Burden in Medicare Beneficiaries with Parkinson’s Disease: Implications by Levodopa Formulation and Disease Severity
Real-World Analysis of Healthcare Utilization, Treatment Patterns, and Economic Burden in Medicare Beneficiaries with Parkinson’s Disease: Implications by Levodopa Formulation and Disease Severity
This study aimed to evaluate healthcare utilization, costs, and treatment patterns of Medicare beneficiaries with Parkinso...
Cost-Effectiveness of the CADScor System in Low-Risk Patients Presenting to the Emergency Department with Chest Pain
Cost-Effectiveness of the CADScor System in Low-Risk Patients Presenting to the Emergency Department with Chest Pain
Studies have shown that up to 13% of patients presenting to the emergency department (ED) with low-risk chest pain receive...
Including Productivity as an Element to Reflect Value of the Treatment: A Systematic Review of Published Health Economic Evaluations
Including Productivity as an Element to Reflect Value of the Treatment: A Systematic Review of Published Health Economic Evaluations
Productivity is utilised inconsistently in value assessment and poses methodological and conceptual challenges for estimat...
Economic Evaluation of Lecanemab for Early Symptomatic Alzheimer's Disease in South Korea
Economic Evaluation of Lecanemab for Early Symptomatic Alzheimer's Disease in South Korea
Alzheimer's disease (AD) exerts a considerable economic burden on South Korea's aging population. Lecanemab, an am...
Cost-Effectiveness of an Insertable Cardiac Arrhythmia Monitor after Non-ST-Elevation Myocardial Infarction in the UK
Cost-Effectiveness of an Insertable Cardiac Arrhythmia Monitor after Non-ST-Elevation Myocardial Infarction in the UK
Patients surviving a non-ST-elevation myocardial infarction (NSTEMI) have an elevated risk of future major adverse cardiov...
Economic Evaluation of Treatment With Trastuzumab Deruxtecan for HER2-Low Advanced or Metastatic Breast Cancer in Previously Treated Patients
Economic Evaluation of Treatment With Trastuzumab Deruxtecan for HER2-Low Advanced or Metastatic Breast Cancer in Previously Treated Patients
This study evaluates the efficiency and budgetary impact of trastuzumab deruxtecan (T-DXd) compared with standard therapy ...
Identifying Potential Gaps in Care for Patients with Higher-Risk Myelodysplastic Syndromes in a Large US Health System
Identifying Potential Gaps in Care for Patients with Higher-Risk Myelodysplastic Syndromes in a Large US Health System
Higher-risk myelodysplastic syndromes (HR-MDS) may be difficult to diagnose because patients present with nonspecific sign...
Estimating Health State Utilities for IDH-Mutant Diffuse Glioma
Estimating Health State Utilities for IDH-Mutant Diffuse Glioma
Isocitrate dehydrogenase-mutant (mIDH) gliomas are malignant central nervous system tumours. After initial resection, pati...
Cost Effectiveness of Recombinant Zoster Vaccine and Live-Attenuated Vaccine Against Herpes Zoster for Adults Aged 50 and Over in China
Cost Effectiveness of Recombinant Zoster Vaccine and Live-Attenuated Vaccine Against Herpes Zoster for Adults Aged 50 and Over in China
Two vaccines against herpes zoster (HZ) are currently authorized for use in China: the adjuvanted recombinant zoster vacci...
A Budget Impact Model of Treatment of Primary Immune Deficiency with Immune Globulin Subcutaneous (Human), 20% (IgPro20) (Hizentra)
A Budget Impact Model of Treatment of Primary Immune Deficiency with Immune Globulin Subcutaneous (Human), 20% (IgPro20) (Hizentra)
Primary immune deficiency (PID) comprises over 400 inborn errors of immunity. Immune globulin replacement therapy (IGRT) i...
Estimating the Value of Adding 30 Days to the 180-Day Market Exclusivity of the First-to-File Generic Drug Manufacturer
Estimating the Value of Adding 30 Days to the 180-Day Market Exclusivity of the First-to-File Generic Drug Manufacturer
As an additional incentive to bringing more generic drugs to more markets sooner, our aim was to estimate the value of add...
Cost Effectiveness of Sequencing Vedolizumab as First-Line Biologic in Ulcerative Colitis and Crohn's Disease in Canada: An Analysis Using Real-World Evidence from the EVOLVE Study
Cost Effectiveness of Sequencing Vedolizumab as First-Line Biologic in Ulcerative Colitis and Crohn's Disease in Canada: An Analysis Using Real-World Evidence from the EVOLVE Study
Vedolizumab is a gut‐selective anti‐lymphocyte trafficking biologic indicated for the treatment of adult patie...
Integrating Multi-Cancer Early Detection (MCED) Tests with Standard Cancer Screening: System Dynamics Model Development and Feasibility Testing
Integrating Multi-Cancer Early Detection (MCED) Tests with Standard Cancer Screening: System Dynamics Model Development and Feasibility Testing
Cancer screening plays a critical role in early disease detection and improving outcomes. In Australia, established screen...
Health Economic Evaluation of Antimicrobial Stewardship, Procalcitonin Testing, and Rapid Blood Culture Identification in Sepsis Care: A 90-Day Model-Based, Cost-Utility Analysis
Health Economic Evaluation of Antimicrobial Stewardship, Procalcitonin Testing, and Rapid Blood Culture Identification in Sepsis Care: A 90-Day Model-Based, Cost-Utility Analysis
We evaluated the cost-effectiveness of a bundled intervention including an antimicrobial stewardship program (ASP), procal...
Clinical Complications and Healthcare Resource Utilization Associated with Conventional Management of Sickle Cell Disease with Recurrent Vaso-occlusive Crises and Transfusion-Dependent β-Thalassemia in Germany
Clinical Complications and Healthcare Resource Utilization Associated with Conventional Management of Sickle Cell Disease with Recurrent Vaso-occlusive Crises and Transfusion-Dependent β-Thalassemia in Germany
The purpose of this study was to describe clinical complications and healthcare resource utilization (HCRU) among patients...
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Obesity is a global health issue with significant economic implications for health systems. Pharmacotherapy, including sem...
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
The authorization of new therapeutic indications for drugs already reimbursed by the Italian National Health Service (NHS)...
Cost-Utility Analysis of LifeVest® in Post-Myocardial Infarction Patients at Risk of Sudden Cardiac Death in England
Cost-Utility Analysis of LifeVest® in Post-Myocardial Infarction Patients at Risk of Sudden Cardiac Death in England
Patients with a left ventricular ejection fraction ≤ 35% are at increased risk of sudden cardiac death (SCD) within ...
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
Disparities in access to oncology medicines in European Union (EU) member states can impact patient outcomes profoundly, w...
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Immune checkpoint inhibitor (ICI)-containing treatment is currently prescribed as first-line treatment for all patients wi...
COVID-19 Vaccine Preferences in China: A Comparison of Discrete Choice Experiment and Profile Case Best–Worst Scaling
COVID-19 Vaccine Preferences in China: A Comparison of Discrete Choice Experiment and Profile Case Best–Worst Scaling
Little is known about the diversity of residents' preferences for COVID-19 vaccines during the time when COVID-19 mana...
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher inc...
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
Given that Korea lacks measures to promote cost-effective prescribing, this study investigated the efficiency of prescribe...
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Many decision-makers have emphasized the importance of leveraging patient experience data to measure unmet need. However, ...
Cost Effectiveness of Left Ventricular Assist Devices (LVADs) as Destination Therapy: A Systematic Review
Cost Effectiveness of Left Ventricular Assist Devices (LVADs) as Destination Therapy: A Systematic Review
Left ventricular assist devices (LVADs) can extend life and improve quality of life among advanced heart failure patients ...
Clinicians’ Preferences for Sphingosine-1-Phosphate Receptor Modulators in Multiple Sclerosis Based on Clinical Management Considerations: A Choice Experiment
Clinicians’ Preferences for Sphingosine-1-Phosphate Receptor Modulators in Multiple Sclerosis Based on Clinical Management Considerations: A Choice Experiment
Four sphingosine-1-phosphate receptor (S1PR) modulators are currently available in the USA for treating relapsing forms of...
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