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Early identification of macrophage activation syndrome secondary to systemic lupus erythematosus with machine learning
Early identification of macrophage activation syndrome secondary to systemic lupus erythematosus with machine learning
The macrophage activation syndrome (MAS) secondary to systemic lupus erythematosus (SLE) is a severe and life-threatening ...
Efficacy and safety study of targeted small-molecule drugs in the treatment of systemic lupus erythematosus
Efficacy and safety study of targeted small-molecule drugs in the treatment of systemic lupus erythematosus
Targeted small-molecule drugs in the treatment of systemic lupus erythematosus (SLE) have attracted increasing attention f...
Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation
Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation
Exploring the pathogenesis of osteoarthritis (OA) is important for its prevention, diagnosis, and treatment. Therefore, we...
Unraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states
Unraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states
This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Eryth...
The role of M1/M2 macrophage polarization in primary Sjogren’s syndrome
The role of M1/M2 macrophage polarization in primary Sjogren’s syndrome
The purpose of this study was to investigate the role of macrophage polarization in the pathogenesis of primary Sjogren...
New molecular targets in the treatment of rheumatoid arthritis
New molecular targets in the treatment of rheumatoid arthritis
Purpose of review This review will discuss selected emerging molecular targets and associated pot
Sodium-glucose cotransporter 2 inhibitors: are they ready for prime time in the management of lupus nephritis?
Sodium-glucose cotransporter 2 inhibitors: are they ready for prime time in the management of lupus nephritis?
Purpose of review Lupus nephritis is a common complication of systemic lupus erythematosus and is
Describing calcium pyrophosphate deposition: undoing the tower of Babel!
Describing calcium pyrophosphate deposition: undoing the tower of Babel!
Purpose of review In 1977, McCarty astutely observed, ‘The variety of names suggested for the con
Emerging biologic therapies for systemic lupus erythematosus
Emerging biologic therapies for systemic lupus erythematosus
Purpose of review The approval of belimumab and anifrolumab has expanded the scope of treatment f
Cardiovascular complications of rheumatoid arthritis
Cardiovascular complications of rheumatoid arthritis
Purpose of review Rheumatoid arthritis (RA) patients remain at higher cardiovascular (CV) risk co
Management of postinfectious inflammatory arthritis
Management of postinfectious inflammatory arthritis
Purpose of review Postinfectious inflammatory arthritis can result from various pathogens, includ
Updates on interstitial lung disease and other selected extra-articular manifestations of rheumatoid arthritis
Updates on interstitial lung disease and other selected extra-articular manifestations of rheumatoid arthritis
Purpose of review To discuss changes in epidemiology, recent advances in understanding of the pat
Autoantibodies in rheumatoid arthritis – rheumatoid factor, anticitrullinated protein antibodies and beyond
Autoantibodies in rheumatoid arthritis – rheumatoid factor, anticitrullinated protein antibodies and beyond
Purpose of review RA is characterized by the presence of autoantibodies among which rheumatoid fa
Monogenic lupus: insights into disease pathogenesis and therapeutic opportunities
Monogenic lupus: insights into disease pathogenesis and therapeutic opportunities
Purpose of review This review aims to provide an overview of the genes and molecular pathways inv
Rheumatoid arthritis: prediction of future clinically-apparent disease, and prevention
Rheumatoid arthritis: prediction of future clinically-apparent disease, and prevention
Purpose of review This review discusses updates in the prediction and prevention of future rheuma
Safety of biologic agents for the management of rheumatic diseases during pregnancy
Safety of biologic agents for the management of rheumatic diseases during pregnancy
Purpose of review To discuss the current understanding regarding the use of biologic therapeutics
Chimeric antigen receptors: “CARs” in the fast lane for rheumatology
Chimeric antigen receptors: “CARs” in the fast lane for rheumatology
Purpose of review Recent advances in hematology-oncology have pioneered cell-mediated elimination
Deep Learning Enables Automatic Detection of Joint Damage Progression in Rheumatoid Arthritis—Model Development and External Validation
Deep Learning Enables Automatic Detection of Joint Damage Progression in Rheumatoid Arthritis—Model Development and External Validation
AbstractObjectives. Although deep learning has demonstrated substantial potential in automatic quantification of joint dam...
Nanoparticle-based pazopanib shows promise in OA
A nanoparticle-based formulation of the anticancer drug pazopanib, which inhibits VEGFR1 and VEGFR2, shows promise as a di...
Reply to: Current classification criteria underestimate the incidence of idiopathic inflammatory myopathies by ignoring subgroups
We thank Giannini et al.1 for their response (Giannini, M. et al. Current classification criteria und...
Current classification criteria underestimate the incidence of idiopathic inflammatory myopathies by ignoring subgroups
We read with great interest the Review article by Khoo et al. (Epidemiology of the idiopathic inflamm...
Low-frequency and rare genetic variants associated with rheumatoid arthritis risk
Low-frequency and rare genetic variants associated with rheumatoid arthritis risk
Rheumatoid arthritis (RA) has an estimated heritability of nearly 50%, which is particularly high in seropositive RA. HLA ...
Author Correction: International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative
National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, ...
Author Correction: Proposals for the rheumatological use of JAK inhibitors
Authors and AffiliationsUniversity della Campania, Department of Precision Medicine, Naples, ItalyFrancesco CicciaUniversi...
Time for a new approach to drug development for rare systemic autoinflammatory diseases
Despite the transformative potential of treatments for systemic autoinflammatory diseases, these conditions remain underfu...
Author Correction: Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells
Author notesThese authors contributed equally: Christian Jorgensen, Danièle Noël.Authors and AffiliationsIRMB, University ...
Pathogenic autoantibody internalization in myositis
Pathogenic autoantibody internalization in myositis
medRxiv - The Preprint Server for Health Sciences
cg05883128 (DDX60) and NR3C2 (CD4 T-cells and B-cells) to Be the Genetic Roots of Systemic Lupus Erythematosus
cg05883128 (DDX60) and NR3C2 (CD4 T-cells and B-cells) to Be the Genetic Roots of Systemic Lupus Erythematosus
medRxiv - The Preprint Server for Health Sciences
Analysis of dietary vitamin C intake levels and the risk of hyperuricemia and gout based on cross-sectional studies and bi-directional Mendelian randomisation
Analysis of dietary vitamin C intake levels and the risk of hyperuricemia and gout based on cross-sectional studies and bi-directional Mendelian randomisation
medRxiv - The Preprint Server for Health Sciences
Endogenous retroelement activation is implicated in IFN-alpha production and anti-CCP autoantibody generation in early RA
Endogenous retroelement activation is implicated in IFN-alpha production and anti-CCP autoantibody generation in early RA
medRxiv - The Preprint Server for Health Sciences
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