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Real-World-Evidence of Digital Health Applications (DiGAs) in Rheumatology: Insights from the DiGAReal Registry

Prescribable digital health applications (DiGAs) present scalable solutions to improve patient self-management in rheumato...

Rheumatology And Therapy

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Effect of Ozoralizumab Administration with or without Methotrexate in Patients with Rheumatoid Arthritis: A Post-Hoc Analysis

Ozoralizumab (OZR) is a novel tumor necrosis factor (TNF) inhibitor that was launched in Japan for treating patients with ...

Rheumatology And Therapy

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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials

We assessed tofacitinib efficacy and safety in ankylosing spondylitis (AS) by body mass index (BMI) category. Data were po...

Rheumatology And Therapy

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Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial

Fatigue is a key symptom in patients with ankylosing spondylitis (AS). The objective of this analysis was to esti...

Rheumatology And Therapy

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Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue

Current literature regarding cancer risk in rheumatic and musculoskeletal diseases (RMDs) is particularly poor and controv...

Rheumatology And Therapy

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The Uncoupling of Disease Activity from Joint Structural Progression in Patients with Rheumatoid Arthritis Treated with Filgotinib

While modern treatments can prevent progressive bone destruction in patients with rheumatoid arthritis (RA) achieving clin...

Rheumatology And Therapy

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Association Between Patient-Reported Pain and Remission or Low Disease Activity in Patients with Rheumatoid Arthritis: Data from RA-BE-REAL Prospective Observational Study

We aim to assess the association of patient-reported pain and remission or low disease activity (LDA) at 3 months...

Rheumatology And Therapy

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Arthralgia and Extraintestinal Manifestations in Crohn’s Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis

Inflammatory bowel disease (IBD) related arthritis is the most prevalent extraintestinal manifestation (EIM) of IBD, rangi...

Rheumatology And Therapy

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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis

Gout is a progressive form of arthritis that causes significant pain and disability. Patients with treatment-refractory (o...

Rheumatology And Therapy

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Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry

Interim analysis of the long-term safety and effectiveness of canakinumab, at a patient level, in the mevalonate kinase de...

Rheumatology And Therapy

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Real-World Persistence and Effectiveness of Upadacitinib versus Other Janus Kinase Inhibitors and Tumor Necrosis Factor Inhibitors in Australian Patients with Rheumatoid Arthritis

This study sought to describe treatment patterns, persistence, and effectiveness of upadacitinib (UPA) alone and compared ...

Rheumatology And Therapy

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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial

Lorecivivint (LOR), a CDC-like kinase/dual-specificity tyrosine kinase (CLK/DYRK) inhibitor thought to modulate inflammato...

Rheumatology And Therapy

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Factors Influencing Treatment Satisfaction and Recognition Gaps Between Physicians and Patients with Systemic Sclerosis

It is important to understand the differences in patient–physician perceptions and factors affecting satisfaction wi...

Rheumatology And Therapy

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Real-World Osteoporosis Treatment Gap and Costs in Spain: Data from Women with a First Fragility Fracture or Diagnosis of Postmenopausal Osteoporosis

Postmenopausal osteoporosis (PMO) increases the risk of fragility fractures (FF), leading to disability, higher mortality,...

Rheumatology And Therapy

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Clinical Validation and Outcome Measures From Bend Ease: A Novel, Sensor-Based Digital Measurement Tool for Assessing At-Home Morning Stiffness and Spinal Range of Motion in Axial Spondyloarthritis

To evaluate the accuracy, reliability, and usability of Bend Ease, a novel smartphone-based digital health technology (DHT...

Rheumatology And Therapy

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Management of pregnant with rheumatoid arthritis: Preconception care, pregnancy and lactation strategies, and maternal-fetal outcomes