SCI Abstract

search
+
Nimodipine attenuates neuroinflammation and delayed apoptotic neuronal death induced by trimethyltin in the dentate gyrus of mice
Nimodipine attenuates neuroinflammation and delayed apoptotic neuronal death induced by trimethyltin in the dentate gyrus of mice
L-type voltage-gated calcium channels (L-VGCCs) are thought to be involved in epileptogenesis and acute excitotoxicity. Ho...
A triterpenoid (corosolic acid) ameliorated AOM-mediated aberrant crypt foci in rats: modulation of Bax/PCNA, antioxidant and inflammatory mechanisms
A triterpenoid (corosolic acid) ameliorated AOM-mediated aberrant crypt foci in rats: modulation of Bax/PCNA, antioxidant and inflammatory mechanisms
Corosolic acid (CA) is a well-known natural pentacyclic triterpene found in numerous therapeutic plants that can exhibit m...
Cytoprotective effect of garlic alone versus co-administration of garlic and resveratrol in adriamycin-induced lung toxicity in albino rat: light microscopic, ultrastructural and immunohistochemical study
Cytoprotective effect of garlic alone versus co-administration of garlic and resveratrol in adriamycin-induced lung toxicity in albino rat: light microscopic, ultrastructural and immunohistochemical study
Adriamycin is a cytotoxic anthracycline antibiotic used to treat a wide variety of cancers. This study was made to detect ...
Harmony in nature's elixir: a comprehensive exploration of ethanol and nano-formulated extracts from Passiflora incarnata leaves: unveiling in vitro cytotoxicity, acute and sub-acute toxicity profiles in Swiss albino mice
Harmony in nature's elixir: a comprehensive exploration of ethanol and nano-formulated extracts from Passiflora incarnata leaves: unveiling in vitro cytotoxicity, acute and sub-acute toxicity profiles in Swiss albino mice
We analyzed the toxic effect of the ethanolic extract of Passiflora incarnata (EEP) and its nanoformulation (N-EEP) in the...
Exploration of N6-methyladenosine modification in ascorbic acid 2-glucoside constructed stem cell sheets
Exploration of N6-methyladenosine modification in ascorbic acid 2-glucoside constructed stem cell sheets
The aim of this study was to explore the mechanism of bone marrow stem cells (BMSCs) sheets constructed with different dos...
Revealing the molecular mechanisms in wound healing and the effects of different physiological factors including diabetes, age, and stress
Revealing the molecular mechanisms in wound healing and the effects of different physiological factors including diabetes, age, and stress
Wounds are the common fates in various microbial infections and physical damages including accidents, surgery, and burns. ...
Mandible development under gestational protein restriction: cellular and molecular mechanisms
Mandible development under gestational protein restriction: cellular and molecular mechanisms
Insufficient evidence regarding how maternal undernutrition affects craniofacial bone development persists. With its uniqu...
Effects of SARS-COV-2 on molecules involved in vascularization and autophagy in placenta tissues
Effects of SARS-COV-2 on molecules involved in vascularization and autophagy in placenta tissues
SARS-CoV-2 infection is considered as a multi-organ disease, and several studies highlighted the relevance of the virus in...
Physical activity enhances the effect of immune checkpoint blockade by inhibiting the intratumoral HIF1-α/CEACM1 axis
Physical activity enhances the effect of immune checkpoint blockade by inhibiting the intratumoral HIF1-α/CEACM1 axis
Immune checkpoint blockade therapy has demonstrated significant therapeutic effects in certain types of cancers. However, ...
Ameliorative effects of Turbinaria ornata extract on hepatocellular carcinoma induced by diethylnitrosamine in-vivo
Ameliorative effects of Turbinaria ornata extract on hepatocellular carcinoma induced by diethylnitrosamine in-vivo
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths and the fifth most common cancer worldw...
SGLT2 inhibitor downregulated oxidative stress via activating AMPK pathway for cardiorenal (CR) protection in CR syndrome rodent fed with high protein diet
SGLT2 inhibitor downregulated oxidative stress via activating AMPK pathway for cardiorenal (CR) protection in CR syndrome rodent fed with high protein diet
This study tested the hypothesis that empagliflozin (EMPA) therapy effectively protected renal and heart functions via dow...
Neurotoxicity of the antineoplastic drugs: “Doxorubicin” as an example
Neurotoxicity of the antineoplastic drugs: “Doxorubicin” as an example
There is an increased prevalence of cancer, and chemotherapy is widely and routinely utilized to manage the majority of ca...
The role and mechanism of β-catenin-mediated skeletal muscle satellite cells in osteoporotic fractures by Jian-Pi-Bu-Shen formula
The role and mechanism of β-catenin-mediated skeletal muscle satellite cells in osteoporotic fractures by Jian-Pi-Bu-Shen formula
Osteoporosis is a metabolic bone disease. β-Catenin is associated with fractures. Jian-Pi-Bu-Shen (JPBS) can promote ...
Serum biochemical evaluation following administration of imidazolyl thiazolidinedione in streptozotocin-induced diabetic rats
Serum biochemical evaluation following administration of imidazolyl thiazolidinedione in streptozotocin-induced diabetic rats
Diabetes mellitus represents a prominent global health concern, characterized by a rising prevalence rate. Type 2 Diabetes...
Type I Diabetes Mellitus impairs cytotoxic immunity through CEACAM5 upregulation in colorectal cancer
Type I Diabetes Mellitus impairs cytotoxic immunity through CEACAM5 upregulation in colorectal cancer
Type 1 diabetes (T1D) is characterized by an autoimmune-mediated destruction of pancreatic beta cells and a chronic inflam...
CLDN11 deficiency upregulates FOXM1 to facilitate breast tumor progression through hedgehog signaling pathway
CLDN11 deficiency upregulates FOXM1 to facilitate breast tumor progression through hedgehog signaling pathway
Claudins (CLDNs) play a crucial role in regulating the permeability of epithelial barriers and can impact tumor behavior t...
Methylglyoxal reduces resistance exercise-induced protein synthesis and anabolic signaling in rat tibialis anterior muscle
Methylglyoxal reduces resistance exercise-induced protein synthesis and anabolic signaling in rat tibialis anterior muscle
Resistance exercise provides significant benefits to skeletal muscle, including hypertrophy and metabolic enhancements, su...
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
Tubular aggregate myopathy (TAM) is a rare myopathy characterized by muscle weakness and myalgia. Muscle fibers from TAM p...
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes
Pyruvate dehydrogenase kinase (PDK), which phosphorylates the pyruvate dehydrogenase complex, regulates glucose metabolism...
The 50th anniversary of the European Society for Muscle Research: a journey through half a century of scientific advances
The 50th anniversary of the European Society for Muscle Research: a journey through half a century of scientific advances
The European Society for Muscle Research (ESMR) started in 1971 as “European Muscle Club” in a joint initiativ...
Unraveling the bidirectional relationship between muscle inflammation and satellite cells activity: influencing factors and insights
Unraveling the bidirectional relationship between muscle inflammation and satellite cells activity: influencing factors and insights
Inflammation stands as a vital and innate function of the immune system, essential for maintaining physiological homeostas...
Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy
Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy
RAG2 deficiency is characterized by a lack of B and T lymphocytes, causing severe lethal infections. Currently, RAG2 defic...
MiR-124-3p inhibits cell stemness in glioblastoma via targeting EPHA2 through ALKBH5-mediated m6A modification
MiR-124-3p inhibits cell stemness in glioblastoma via targeting EPHA2 through ALKBH5-mediated m6A modification
Glioblastoma (GBM) is the most aggressive form of glioma, characterized by high mortality and poor prognosis. Dysregulatio...
Adiponectin-induced activation of ERK1/2 drives fibrosis in retinal pigment epithelial cells
Adiponectin-induced activation of ERK1/2 drives fibrosis in retinal pigment epithelial cells
Adiponectin (APN), a vasoactive cytokine produced by adipocytes, has emerged as a critical player in retinal diseases. Ren...
Emodin regulated lactate metabolism by inhibiting MCT1 to delay non-small cell lung cancer progression
Emodin regulated lactate metabolism by inhibiting MCT1 to delay non-small cell lung cancer progression
Lung cancer is one of the most common malignant tumors in the world, with high incidence rate and mortality. Monocarboxyla...
Dexmedetomidine mitigates lidocaine-induced spinal cord injury by repressing ferritinophagy-mediated ferroptosis by increasing CISD2 expression in rat models
Dexmedetomidine mitigates lidocaine-induced spinal cord injury by repressing ferritinophagy-mediated ferroptosis by increasing CISD2 expression in rat models
Dexmedetomidine (DEX) has been confirmed to exert neuroprotective effects in various nerve injury models by regulating fer...
Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1
Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1
The methods available for treating metastatic Ewing sarcoma (ES) are inadequate; thus, innovative therapeutic approaches n...
Establishment and characterization of NCC-SS6-C1: a novel patient-derived cell line of synovial sarcoma
Establishment and characterization of NCC-SS6-C1: a novel patient-derived cell line of synovial sarcoma
Synovial sarcoma (SS) is identified as a sarcoma with monomorphic blue spindle cells that display variable epithelial diff...
The vascular influence of melatonin on endothelial response to angiotensin II in diabetic rat aorta
The vascular influence of melatonin on endothelial response to angiotensin II in diabetic rat aorta
The current study explored melatonin (MEL) and its receptors, including MEL type 1 receptor (MT1) receptor and MEL type 2 ...
Cyclic tensile stress promotes osteogenic differentiation via upregulation of Piezo1 in human dental follicle stem cells
Cyclic tensile stress promotes osteogenic differentiation via upregulation of Piezo1 in human dental follicle stem cells
As periodontal progenitor cells, human dental follicle stem cells (hDFCs) play an important role in regenerative medicine ...
Load More
format_indent_increase