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Platelet-Rich Plasma-Embedded Porous Polycaprolactone Film with a Large Surface Area for Effective Hemostasis
Platelet-Rich Plasma-Embedded Porous Polycaprolactone Film with a Large Surface Area for Effective Hemostasis
Uncontrollable and widespread bleeding caused by surgery or sudden accidents can lead to death if not treated with appropr...
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts
Vascular grafts are mainly composed of synthetic materials, but are prone to thrombosis and intimal hyperplasia at small d...
Zinc-Alpha-2-Glycoprotein Peptide Downregulates Type I and III Collagen Expression via Suppression of TGF-β and p-Smad 2/3 Pathway in Keloid Fibroblasts and Rat Incisional Model
Zinc-Alpha-2-Glycoprotein Peptide Downregulates Type I and III Collagen Expression via Suppression of TGF-β and p-Smad 2/3 Pathway in Keloid Fibroblasts and Rat Incisional Model
Keloids and hypertrophic scars result from abnormal collagen accumulation and the inhibition of its degradation. Although ...
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring
Abnormal scarring imposes considerable challenges and burdens on the lives of patients and healthcare system. Macrophages ...
Reduced Cell Migration in Human Chondrocyte Sheets Increases Tissue Stiffness and Cartilage Protein Production
Reduced Cell Migration in Human Chondrocyte Sheets Increases Tissue Stiffness and Cartilage Protein Production
Chondrogenic differentiation medium (CDM) is usually used to maintain chondrogenic activity during chondrocyte sheet produ...
Multifunctional Microneedle Patch with Diphlorethohydroxycarmalol for Potential Wound Dressing
Multifunctional Microneedle Patch with Diphlorethohydroxycarmalol for Potential Wound Dressing
Treatment of skin wounds with diverse pathological characteristics presents significant challenges due to the limited spec...
Evaluation of Bi-layer Silk Fibroin Grafts for Inlay Vaginoplasty in a Rat Model
Evaluation of Bi-layer Silk Fibroin Grafts for Inlay Vaginoplasty in a Rat Model
Autologous tissues derived from bowel, buccal mucosa and skin are primarily used to repair or replace diseased vaginal seg...
Rapamycin Attenuates H2O2-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts
Rapamycin Attenuates H2O2-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts
Oxidative stress plays an important role in the skin aging process. Rapamycin has been shown to have anti-aging effects, b...
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation
Osteoarthritis (OA), a degenerative joint disorder, is a major reason of disability in adults. Accumulating evidences have...
The Effect of Platelet Fibrin Plasma (PFP) on Postoperative Refractory Wounds: Physiologically Concentrated Platelet Plasma in Wound Repair
The Effect of Platelet Fibrin Plasma (PFP) on Postoperative Refractory Wounds: Physiologically Concentrated Platelet Plasma in Wound Repair
Surgical wounds that can’t complete primary healing three weeks after surgery are called postoperative refractory wo...
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cel...
Preparation and Evaluation of Poloxamer/Carbopol In-Situ Gel Loaded with Quercetin: In-Vitro Drug Release and Cell Viability Study
Preparation and Evaluation of Poloxamer/Carbopol In-Situ Gel Loaded with Quercetin: In-Vitro Drug Release and Cell Viability Study
Periodontitis is a severe chronic inflammatory disease, whose traditional systemic antimicrobial therapy faces great limit...
A Study on iPSC-Associated Factors in the Generation of Hepatocytes
A Study on iPSC-Associated Factors in the Generation of Hepatocytes
Hepatocytes are an attractive cell source in hepatic tissue engineering because they are the primary cells of the liver, m...
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Priming strategies that improve the functionality of MSCs may be required to address issues limiting successful clinical t...
In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin
In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin
Injectable platelet-rich fibrin (iPRF), a liquid form of PRF that is prepared from peripheral blood without anticoagulants...
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment
Tendinopathy is a chronic tendon disease. Mesenchymal stem cells (MSCs), known for their anti-inflammatory properties, may...
Inertial measurement units to evaluate the efficacity of Equino Varus Foot surgery in post stroke hemiparetic patients: a feasibility study
Inertial measurement units to evaluate the efficacity of Equino Varus Foot surgery in post stroke hemiparetic patients: a feasibility study
This study evaluates the gait analysis obtained by Inetial Measurement Units (IMU) before and after surgical management of...
Acceptability, validity and responsiveness of inertial measurement units for assessing motor recovery after gene therapy in infants with early onset spinal muscular atrophy: a prospective cohort study
Acceptability, validity and responsiveness of inertial measurement units for assessing motor recovery after gene therapy in infants with early onset spinal muscular atrophy: a prospective cohort study
Onasemnogene abeparvovec gene replacement therapy (GT) has changed the prognosis of patients with spinal muscular atrophy ...
Left ventricular assist device temporary explantation as a strategy for infection control in a pediatric patient
Left ventricular assist device temporary explantation as a strategy for infection control in a pediatric patient
We report a case of temporary Berlin Heart EXCOR® explantation in a pediatric patient with idiopathic dilated cardiom...
Mechanical support for bridge to transplant in an infant with post-cardiotomy end-stage heart failure and complete heart block: report of a case
Mechanical support for bridge to transplant in an infant with post-cardiotomy end-stage heart failure and complete heart block: report of a case
The patient was diagnosed with perimembranous ventricular septal defect (VSD). She underwent VSD closure and muscle bundle...
Management of aortic valve insufficiency in patients with continuous-flow left ventricular assist device: a republication of the review published in Japanese Journal of Artificial Organs
Management of aortic valve insufficiency in patients with continuous-flow left ventricular assist device: a republication of the review published in Japanese Journal of Artificial Organs
Since 2011, implantable ventricular assist devices have been a standard treatment for severe heart failure alongside heart...
Patient management important for long-term support beyond 5 years in the BTT: republication of the article published in the Japanese Journal of Artificial Organs
Patient management important for long-term support beyond 5 years in the BTT: republication of the article published in the Japanese Journal of Artificial Organs
Heart transplantation is considered to be the best treatment for severe heart failure refractory to medical therapy, impro...
Current issues of destination therapy in Japan: to achieve 5−year or even longer survival
Current issues of destination therapy in Japan: to achieve 5−year or even longer survival
In April 2021, destination therapy (DT) was finally approved in Japan. Since DT does not aim at heart transplantation (HT)...
Durable left ventricular assist devices in pediatrics: impact of body size on outcomes and size limitations
Durable left ventricular assist devices in pediatrics: impact of body size on outcomes and size limitations
Despite the range of body sizes in children, few ventricular assist devices (VAD) exist to support pediatric patients with...
Contemporary optimal therapeutic strategy with escalation/de-escalation of temporary mechanical circulatory support in patients with cardiogenic shock and advanced heart failure in Japan
Contemporary optimal therapeutic strategy with escalation/de-escalation of temporary mechanical circulatory support in patients with cardiogenic shock and advanced heart failure in Japan
The utilization of temporary mechanical circulatory support (MCS) in the management of cardiogenic shock is experiencing a...
Axial-flow polymer bridge pump with hydrodynamic bearings
Axial-flow polymer bridge pump with hydrodynamic bearings
A portable axial-flow polymer bridge pump with hydrodynamic bearings has been developed for bridge-to-bridge use. The pump...
Impact of the spleen size on short-term prognosis in patients with cardiogenic shock receiving Impella-incorporated temporary mechanical circulatory support
Impact of the spleen size on short-term prognosis in patients with cardiogenic shock receiving Impella-incorporated temporary mechanical circulatory support
The spleen size may be associated with mortality and morbidity in patients with heart failure, whereas its clinical implic...
Advanced roll porous scaffold 3D bioprinting technology
Advanced roll porous scaffold 3D bioprinting technology
Improvements in the roll porous scaffold (RPS) 3D bioproduction technology will increase print density of 10−15&...
A compact machine perfusion device for whole blood perfusion in isolated rat liver
A compact machine perfusion device for whole blood perfusion in isolated rat liver
We established a compact machine perfusion system for whole blood perfusion of rat liver by making use of oxygenation filt...
Exploring the role of plasmapheresis prior to thyroidectomy in managing thyrotoxicosis: a comprehensive scoping review
Exploring the role of plasmapheresis prior to thyroidectomy in managing thyrotoxicosis: a comprehensive scoping review
A thyroid storm is the most extreme and life-threatening presentation of thyrotoxicosis. Thyroidectomy can be used for def...
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