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Gynura divaricata (L.) DC. promotes diabetic wound healing by activating Nrf2 signaling in diabetic rats
Gynura divaricata (L.) DC. promotes diabetic wound healing by activating Nrf2 signaling in diabetic rats
Chronic diseases like diabetes, which affecting 463 million people worldwide, is a major public health concern (Chang and ...
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication
Jiawei Buzhong Yiqi decoction ameliorates polycystic ovary syndrome via oocyte-granulosa cell communication
Ethnopharmacological relevanceJiawei Buzhong Yiqi Decoction (JWBZYQ), from records of Fuqingzhu Nvke, is a classical formu...
SuanZaoRen decoction alleviates neuronal loss, synaptic damage and ferroptosis of AD via activating DJ-1/Nrf2 signaling pathway
SuanZaoRen decoction alleviates neuronal loss, synaptic damage and ferroptosis of AD via activating DJ-1/Nrf2 signaling pathway
Ethnopharmacological relevanceSuanZaoRen Decoction (SZRD), a famous herbal prescription, and has been widely proven to hav...
Huang-Lian-Jie-Du decoction drug-containing serum inhibits IL-1β secretion from D-glucose and PA induced BV2 cells via autophagy/NLRP3 signaling
Huang-Lian-Jie-Du decoction drug-containing serum inhibits IL-1β secretion from D-glucose and PA induced BV2 cells via autophagy/NLRP3 signaling
According to the data showed by the International Diabetes Federation (Tang et al., 2023): in 2021, there were 537 million...
Phytochemical characterization and phospholipase A2 inhibitory effect of Vitex negundo L. root extracts
Phytochemical characterization and phospholipase A2 inhibitory effect of Vitex negundo L. root extracts
Venom is a type of zootoxin that is transferred in to the body of prey through bite or sting in a process called envenomat...
Elucidation for the pharmacological effects and mechanism of Shen Bai formula in treating myocardial injury based on energy metabolism and serum metabolomic approaches
Elucidation for the pharmacological effects and mechanism of Shen Bai formula in treating myocardial injury based on energy metabolism and serum metabolomic approaches
Myocardial injury is the pathological basis of many cardiomyopathies, such as viral myocarditis (VMC) and its sequelae. VM...
Investigation of the material basis and mechanism of Lizhong decoction in ameliorating ulcerative colitis based on spectrum-effect relationship and network pharmacology
Investigation of the material basis and mechanism of Lizhong decoction in ameliorating ulcerative colitis based on spectrum-effect relationship and network pharmacology
Ulcerative colitis (UC), a chronic non-specific inflammatory bowel disease (IBD) involving the colon and rectum, is charac...
Network pharmacology, molecular docking and experimental study of CEP in nasopharyngeal carcinoma
Network pharmacology, molecular docking and experimental study of CEP in nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is a malignant neoplasm intimately associated with particular geographic locations and char...
Xinfeng capsule inhibits lncRNA NONHSAT227927.1/TRAF2 to alleviate NF-κB-p65-induced immuno-inflammation in ankylosing spondylitis
Xinfeng capsule inhibits lncRNA NONHSAT227927.1/TRAF2 to alleviate NF-κB-p65-induced immuno-inflammation in ankylosing spondylitis
Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease (Ma et al., 2022; Zhao et al., 2023), primarily im...
Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol
Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol
Rice, a vital staple crop cultivated worldwide, is the primary dietary component for a substantial segment of the global p...
Elucidating the anti-inflammatory activity of platycodins in lung inflammation through pulmonary distribution dynamics and grey relational analysis of cytokines
Elucidating the anti-inflammatory activity of platycodins in lung inflammation through pulmonary distribution dynamics and grey relational analysis of cytokines
Platycodonis Radix (PR), the root of Platycodon grandiflorum (Jacq.), is a traditional herbal medicine used for treating l...
Exploring the effect of Anshen Dingzhi prescription on hippocampal mitochondrial signals in single prolonged stress mouse model
Exploring the effect of Anshen Dingzhi prescription on hippocampal mitochondrial signals in single prolonged stress mouse model
Post-traumatic stress disorder (PTSD) is a mental disorder caused by suddenly experiencing or witnessing psychologically t...
Qing-Re-Chu-shi decoction ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice through anti-inflammation and immunoregulatory mechanisms
Qing-Re-Chu-shi decoction ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice through anti-inflammation and immunoregulatory mechanisms
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by eczematous lesions, intense itch, and sign...
Danhong formula alleviates endothelial dysfunction and reduces blood pressure in hypertension by regulating MicroRNA 24 - Phosphatidylinositol 3-Kinase-Serine/Threonine Kinase- Endothelial Nitric Oxide Synthase axis
Danhong formula alleviates endothelial dysfunction and reduces blood pressure in hypertension by regulating MicroRNA 24 - Phosphatidylinositol 3-Kinase-Serine/Threonine Kinase- Endothelial Nitric Oxide Synthase axis
Essential hypertension (EH), a systemic disease caused by genetic and environmental factors, is one of the important risk ...
Danggui Buxue Tang improves therapeutic efficacy of doxorubicin in triple negative breast cancer via ferroptosis
Danggui Buxue Tang improves therapeutic efficacy of doxorubicin in triple negative breast cancer via ferroptosis
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks expression of estrogen receptor (ER), proges...
Effective constituents and protective effect of Mudan granules against Schwann cell injury
Effective constituents and protective effect of Mudan granules against Schwann cell injury
According to the International Diabetes Federation, approximately 537 million adults aged 20–79 years were diagnosed with ...
Ayahuasca and its major component harmine promote antinociceptive effects in mouse models of acute and chronic pain
Ayahuasca and its major component harmine promote antinociceptive effects in mouse models of acute and chronic pain
Chronic pain is a major cause of suffering and distress to patients and affects millions of people worldwide (Battaglia et...
Danggui Shaoyao San protects cyclophosphamide-induced premature ovarian failure by inhibiting apoptosis and oxidative stress through the regulation of the SIRT1/p53 signaling pathway
Danggui Shaoyao San protects cyclophosphamide-induced premature ovarian failure by inhibiting apoptosis and oxidative stress through the regulation of the SIRT1/p53 signaling pathway
Premature ovarian failure (POF) is the ovarian function loss, leading to amenorrhea among females of childbearing age befo...
Sedative and hypnotic effects of Polygala tenuifolia willd. saponins on insomnia mice and their targets
Sedative and hypnotic effects of Polygala tenuifolia willd. saponins on insomnia mice and their targets
Characterized by difficulty falling asleep, short sleep duration, and poor sleep quality (Buysse, 2013), insomnia has beco...
Protective effects of Tinospora cordifolia miers extract against hepatic and neurobehavioral deficits in thioacetamide-induced hepatic encephalopathy in rats via modulating hyperammonemia and glial cell activation
Protective effects of Tinospora cordifolia miers extract against hepatic and neurobehavioral deficits in thioacetamide-induced hepatic encephalopathy in rats via modulating hyperammonemia and glial cell activation
Hepatic encephalopathy (HE) is characterised by varying range of neurological complications including cognitive and motor ...
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway
Diabetes-associated cognitive dysfunction (DACD) is a common central nervous system complication of diabetes mellitus (DM)...
Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats
Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats
The gastrointestinal mucosa becomes injured when exposed to acid at a high enough concentration for an extended period, wh...
Maca roots: A potential therapeutic in the management of metabolic disorders through the modulation of metabolic biochemical markers in rats fed high-fat high-carbohydrate diet
Maca roots: A potential therapeutic in the management of metabolic disorders through the modulation of metabolic biochemical markers in rats fed high-fat high-carbohydrate diet
Metabolic syndrome (MetS) is a cluster of conditions that occur together, including obesity, insulin resistance, atherogen...
Modified Bushen Yiqi Formula mitigates pulmonary inflammation and airway remodeling by inhibiting neutrophils chemotaxis and IL17 signaling pathway in rats with COPD
Modified Bushen Yiqi Formula mitigates pulmonary inflammation and airway remodeling by inhibiting neutrophils chemotaxis and IL17 signaling pathway in rats with COPD
Chronic obstructive pulmonary disease (COPD) poses a substantial global epidemiological challenge, ranking as the third le...
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis
Inflammatory bowel disease (IBD) is an umbrella term for chronic diseases that produce inflammation in the digestive syste...
Comparative studies on the chemical composition and pharmacological effects of vinegar-processed antler glue modified from Lei Gong Pao Zhi Lun and traditional water-processed antler glue
Comparative studies on the chemical composition and pharmacological effects of vinegar-processed antler glue modified from Lei Gong Pao Zhi Lun and traditional water-processed antler glue
According to the World Health Organization (WHO) definition, infertility is a disease of the male or female reproductive s...
Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death
Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death
Liver fibrosis (LF) is the massive deposition of intrahepatic extracellular matrix (ECM) that occurs in most chronic hepat...
Molecular mechanism of Gan-song Yin inhibiting the proliferation of renal tubular epithelial cells by regulating miR-21-5p in adipocyte exosomes
Molecular mechanism of Gan-song Yin inhibiting the proliferation of renal tubular epithelial cells by regulating miR-21-5p in adipocyte exosomes
Ethnopharmacological relevanceGan-song Yin is derived from the classic ancient prescription " Gan-song pill " for the trea...
Integrating network pharmacology and experimental verification to explore the mucosal protective effect of Chimonanthus nitens Oliv. Leaf Granule on ulcerative colitis
Integrating network pharmacology and experimental verification to explore the mucosal protective effect of Chimonanthus nitens Oliv. Leaf Granule on ulcerative colitis
Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease mainly located in the rectum and colon. The ex...
L-Borneol promotes skin flap survival by regulating HIF-1α/NF-κB pathway
L-Borneol promotes skin flap survival by regulating HIF-1α/NF-κB pathway
A skin flap is a dynamic tissue made up of skin tissue with underlying blood vessels. Skin flaps are used for wound healin...
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