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Prevalence and Predictors of Response to Antifibrotics in Long-Term Survivors with Idiopathic Pulmonary Fibrosis
Prevalence and Predictors of Response to Antifibrotics in Long-Term Survivors with Idiopathic Pulmonary Fibrosis
The natural history of IPF remains unpredictable despite antifibrotic treatment. In addition, some patients discontinue tr...
Differences in Blood Eosinophil Level During Stable Disease and During Exacerbation of COPD and Exacerbation Risks
Differences in Blood Eosinophil Level During Stable Disease and During Exacerbation of COPD and Exacerbation Risks
Although blood eosinophil count (BEC) has been extensively studied as a biomarker in chronic obstructive pulmonary disease...
Toll-Like Receptor 4 and 8 are Overexpressed in Lung Biopsies of Human Non-small Cell Lung Carcinoma
Toll-Like Receptor 4 and 8 are Overexpressed in Lung Biopsies of Human Non-small Cell Lung Carcinoma
Lung cancer is the leading cause of cancer death worldwide which includes two main types of carcinoma distinguished in non...
FLRT3 Overexpression Attenuates Ischemia–Reperfusion Induced Vascular Hyperpermeability and Lung Injury Through RND3
FLRT3 Overexpression Attenuates Ischemia–Reperfusion Induced Vascular Hyperpermeability and Lung Injury Through RND3
Pulmonary ischemia/reperfusion injury (IRI) causes endothelial barrier dysfunction and increased vascular permeability. Fi...
Predictors of Long-Term Survival in Patients with Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry
Predictors of Long-Term Survival in Patients with Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry
We used data from the IPF-PRO Registry of patients with idiopathic pulmonary fibrosis (IPF) to identify characteristics th...
Supratherapeutic Inhaled Corticosteroid Use in Patients Initiating on Biologic Therapies for Severe Asthma: A Nationwide Cohort Study
Supratherapeutic Inhaled Corticosteroid Use in Patients Initiating on Biologic Therapies for Severe Asthma: A Nationwide Cohort Study
In severe asthma, intensive (“supratherapeutic”) doses of inhaled corticosteroids (ICS) are often used. The pr...
SIRT2 Regulates Apoptosis Signaling in Hyperoxic Acute Lung Injury
SIRT2 Regulates Apoptosis Signaling in Hyperoxic Acute Lung Injury
Oxygen therapy is helpful for patients with breathing difficulties; however, sustained supplementation with high-concentra...
Serum Soluble Toll-Like Receptor 4 is a Predictive Biomarker for Acute Exacerbation and Prognosis of Idiopathic Pulmonary Fibrosis: A Retrospective Study
Serum Soluble Toll-Like Receptor 4 is a Predictive Biomarker for Acute Exacerbation and Prognosis of Idiopathic Pulmonary Fibrosis: A Retrospective Study
Toll-like receptor 4 (TLR4) is a transmembrane receptor promoting pro-inflammatory signalling, that is associated with the...
MIP-3-Alpha and MIP-3-Beta as Early Predictors of Pneumonia in Polytraumatized Patients
MIP-3-Alpha and MIP-3-Beta as Early Predictors of Pneumonia in Polytraumatized Patients
Pneumonia is one of the most common complications in patients suffering multiple traumas and is associated with an excepti...
Factors Influencing the Efficacy and Safety of Monoclonal Antibody Biologics in Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials
Factors Influencing the Efficacy and Safety of Monoclonal Antibody Biologics in Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials
Monoclonal antibody therapies targeting specific inflammatory pathways have shown potential in treating chronic obstructiv...
The Role of HDAC3 in Pulmonary Diseases
The Role of HDAC3 in Pulmonary Diseases
Histone deacetylases (HDACs), a class of enzymes involved in epigenetic modifications, play a pivotal role in modulating c...
Effect of Electronic Cigarette Vapour Exposure on Ca- and cAMP-Dependent Ion Transport in Human Airway Epithelial Cells
Effect of Electronic Cigarette Vapour Exposure on Ca- and cAMP-Dependent Ion Transport in Human Airway Epithelial Cells
The popularity of electronic cigarettes (e-cigarettes) has grown exponentially over the past few years, and teenagers now ...
Comparative Efficacy of CFTR Modulators: A Network Meta-analysis
Comparative Efficacy of CFTR Modulators: A Network Meta-analysis
The objective was to study comparative efficacies of cystic fibrosis transmembrane conductance regulator (CFTR) modulators...
Plasma Reticulocalbin 3 (RCN3) is a Novel Biomarker for the Early Diagnosis of Hepatopulmonary Syndrome in Cirrhotic Patients
Plasma Reticulocalbin 3 (RCN3) is a Novel Biomarker for the Early Diagnosis of Hepatopulmonary Syndrome in Cirrhotic Patients
Hepatopulmonary syndrome (HPS) is a severe complication in cirrhotic patients and characterized by abnormal intrapulmonary...
Relationship of Lung Function and the Preserved Ratio Impaired Spirometry Pattern with Aortic and Left Ventricular Structure and Function on Magnetic Resonance Imaging: The Jackson Heart Study
Relationship of Lung Function and the Preserved Ratio Impaired Spirometry Pattern with Aortic and Left Ventricular Structure and Function on Magnetic Resonance Imaging: The Jackson Heart Study
Low lung function and Preserved Ratio Impaired Spirometry (PRISm) have been associated with increased co-morbid cardiovasc...
Update 2025: Management of Non‑Small-Cell Lung Cancer
Update 2025: Management of Non‑Small-Cell Lung Cancer
Lung cancer remains the leading cause of cancer-related mortality worldwide. Since 2024, the non–small-cell...
High-Density Lipoprotein Cholesterol Trajectories and Lung Function Decline: A Prospective Cohort Study
High-Density Lipoprotein Cholesterol Trajectories and Lung Function Decline: A Prospective Cohort Study
Cholesterol regulation is essential to maintain pulmonary homeostasis. Studies suggest that increased high-density lipopro...
The Role of Triple CFTR Modulator Therapy in Reducing Systemic Inflammation in Cystic Fibrosis
The Role of Triple CFTR Modulator Therapy in Reducing Systemic Inflammation in Cystic Fibrosis
Cystic fibrosis (CF) is a genetic disease caused by mutations in the CFTR gene, leading to multisystemic complications, pa...
Atypical surge of hospitalized and severe cases of pertussis: A single center 19-years study from China
Volume 30, Issue 6, November–December 2024, Pages 636-638Author links open overlay panelY. Hu a 1, L. Wang b 1, K. Yao a, ...
Complete response to mTOR inhibitor following JAKi failure in severe pulmonary sarcoidosis
Volume 30, Issue 6, November–December 2024, Pages 639-641Author links open overlay panelR. Hindré a b, V. Besnard b, F. Ko...
The Brompton breathing pattern assessment tool (BPAT): Portuguese translation and cultural adaptation
Volume 30, Issue 6, November–December 2024, Pages 646-647Author links open overlay panelR. Vilarinho a b, C. Ribeiro c d, ...
Late-onset endobronchial metastasis of oncocytic cell thyroid carcinoma
Volume 30, Issue 6, November–December 2024, Pages 650-652Author links open overlay panelS. Ielo a, A. Campione b, R. Scala...
Delays have dangerous ends: Tuberculosis diagnosis delay in Portugal, a qualitative study
Volume 30, Issue 6, November–December 2024, Pages 653-658Author links open overlay panelT. Silva a 1, A. Aguiar b c d 1, A...
Perceptions of the Portuguese population on vaccination – The specific view of Chronic Respiratory Disease patients
Volume 30, Issue 6, November–December 2024, Pages 663-667Author links open overlay panelG.M. Victorino a, I. Saraiva b, B....
A rare case of pneumocystosis under anti-PD-L1 therapy
Volume 30, Issue 6, November–December 2024, Pages 671-672Author links open overlay panelMaria João Santos a, Maria João Ca...
Sclerosing pneumocytoma with rosette structure mimicking carcinoid: A diagnostic pitfall of intraoperative consultation
Volume 30, Issue 6, November–December 2024, Pages 675-678Author links open overlay panelH. Tang, X. He, Y. Chen, W. Xu, J....
Differences in clinical characteristics between coronavirus disease 2019 (COVID-19) and influenza: a systematic review and meta-analysis
Differences in clinical characteristics between coronavirus disease 2019 (COVID-19) and influenza: a systematic review and meta-analysis
The coronavirus disease 2019 (COVID-19) epidemic has brought major challenges to the global health system, and influenza i...
Trends in low global warming potential inhaler prescribing: A UK-wide cohort comparison from 2018–2024
Trends in low global warming potential inhaler prescribing: A UK-wide cohort comparison from 2018–2024
We performed a retrospective cohort analysis comparing trends in low global warming potential (GWP) inhaler prescribing in...
Burden of illness among patients with asthma prescribed inhaled corticosteroids/long-acting β2-agonists
Burden of illness among patients with asthma prescribed inhaled corticosteroids/long-acting β2-agonists
Inhaled corticosteroids (ICS) plus long-acting β2-agonists (LABA) are recommended for maintenance-only or maintenance...
Assessing competence of primary care respiratory healthcare professionals to deliver a psychologically-based intervention for people with COPD: results from the TANDEM study
Assessing competence of primary care respiratory healthcare professionals to deliver a psychologically-based intervention for people with COPD: results from the TANDEM study
Management of long-term conditions is a significant challenge in contemporary health care as people often require support ...
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