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From Glucotoxicity to Lung Injury: Emerging Perspectives on Diabetes-Associated Respiratory Complications
From Glucotoxicity to Lung Injury: Emerging Perspectives on Diabetes-Associated Respiratory Complications
Emerging evidence highlights glucose toxicity as a pivotal driver of diabetic respiratory complications, characterized by ...
ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry
ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry
The International Classification of Diseases (ICD) system plays a key role in health data classification but currently lac...
Evidence that Mast Cells Regulate the Cough Hypersensitivity Associated with Eosinophilic Bronchitis
Evidence that Mast Cells Regulate the Cough Hypersensitivity Associated with Eosinophilic Bronchitis
Eosinophils have been implicated as key effectors in the emergence of chronic cough. But causality has not been firmly est...
Airway Mucus Plugs in Patients with Chronic Cough: A Single-Center Observational Study
Airway Mucus Plugs in Patients with Chronic Cough: A Single-Center Observational Study
This study investigated the prevalence of mucus plugs and their clinical associations in patients with chronic cough. Ches...
Lung Tissue Compliance Interacts with Smooth Muscle and Drives Hyperresponsiveness in Mice with Experimental Asthma
Lung Tissue Compliance Interacts with Smooth Muscle and Drives Hyperresponsiveness in Mice with Experimental Asthma
A recent study on BALB/c and C57BL/6 mice demonstrated a clear lack of association between the in vivo response to nebuliz...
Stratifying GAP Stages by  rs35705950 T-Allele Carriage Refines Survival Prediction in IPF
Stratifying GAP Stages by rs35705950 T-Allele Carriage Refines Survival Prediction in IPF
The genetic contribution to idiopathic pulmonary fibrosis (IPF) has become increasingly evident, enabling its translation ...
Unnerving Cough in CANVAS: Cough Hypersensitivity Despite Airway Nerve Depletion
Unnerving Cough in CANVAS: Cough Hypersensitivity Despite Airway Nerve Depletion
Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a genetic neurodegenerative condition asso...
Serum Cytokeratin 18 and Fragment as Biomarkers for Severity and Prognosis in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Serum Cytokeratin 18 and Fragment as Biomarkers for Severity and Prognosis in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Cytokeratin (CK)18 is present in the bronchi and alveolar epithelium of the lung, and its cleavage product, CK-18M30, serv...
Modified Tracheobronchoplasty for Chronic Cough Due to Excessive Dynamic Airway Collapse: A Case Series
Modified Tracheobronchoplasty for Chronic Cough Due to Excessive Dynamic Airway Collapse: A Case Series
Morice AH, Millqvist E, Bieksiene K et al (2020) ERS guidelines on the diagnosis and treatment of chronic cough in adults ...
Sputum Transcriptomic Analysis and Clustering Reveals Insight Into Asthma Heterogeneity
Sputum Transcriptomic Analysis and Clustering Reveals Insight Into Asthma Heterogeneity
Asthma is a heterogenous disease shaped by different inflammatory pathways. The aim is to investigate transcriptomic profi...
Changes in Lung Function and Patient-Reported Outcomes in Patients with Idiopathic Pulmonary Fibrosis
Changes in Lung Function and Patient-Reported Outcomes in Patients with Idiopathic Pulmonary Fibrosis
We evaluated relationships between changes in lung function and changes in patient-reported outcomes (PROs) in 736 patient...
Age-Dependent Risk of Bronchial Asthma Exacerbation in Respiratory Syncytial Virus Co-infection
Age-Dependent Risk of Bronchial Asthma Exacerbation in Respiratory Syncytial Virus Co-infection
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are common viral etiologies of respiratory infections. ...
Emerging Therapeutics in COPD: Mapping Innovation to Treatable Traits
Emerging Therapeutics in COPD: Mapping Innovation to Treatable Traits
Chronic Obstructive Pulmonary Disease (COPD) is a complex, heterogeneous condition characterized by diverse clinical pheno...
Neuroinflammatory Consequences of Rhinovirus Infection in Human Epithelial and Neuronal Models
Neuroinflammatory Consequences of Rhinovirus Infection in Human Epithelial and Neuronal Models
Rhinovirus (RV) is the leading cause of exacerbations of lung disease. A sensory neuronal model, derived from human dental...
FUNDC1 Promoted Ferroptosis via JNK Pathway in Cigarette Smoking-Induced Chronic Obstructive Pulmonary Disease
FUNDC1 Promoted Ferroptosis via JNK Pathway in Cigarette Smoking-Induced Chronic Obstructive Pulmonary Disease
Cigarette smoking (CS), the major risk factor for chronic obstructive pulmonary disease (COPD), induces oxidative stress, ...
The Down-Regulation of Lactoferrin Expression Induced by Cigarette Smoke can Induce Ferroptosis in COPD
The Down-Regulation of Lactoferrin Expression Induced by Cigarette Smoke can Induce Ferroptosis in COPD
Lactoferrin (LTF) plays a crucial role in iron homeostasis, immune response, and inflammation. In the context of chronic o...
Fatty Acids Dysregulation Correlates with Lung Function in Idiopathic Pulmonary Fibrosis
Fatty Acids Dysregulation Correlates with Lung Function in Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor survival rate and undefined molecular mechan...
Reliability and validity of the Chester step test in patients with interstitial lung disease
Volume 30, Issue 6, November–December 2024, Pages 570-576Author links open overlay panel, , , , AbstractBackgroundThe Ches...
Developing an interprofessional collaboration for COPD patients in primary care: a participatory action research approach
Developing an interprofessional collaboration for COPD patients in primary care: a participatory action research approach
Chronic obstructive pulmonary disease (COPD) is a respiratory disease which may significantly impact health status. To red...
Refining mild asthma phenotyping with FeNO: a population-based evaluation
Refining mild asthma phenotyping with FeNO: a population-based evaluation
The utility of fractional exhaled nitric oxide (FeNO) was evaluated alongside blood eosinophils in phenotyping mild asthma...
Chronic Obstructive Pulmonary Disease and Lung Cancer: A Meta-Analysis of Risk Association
Chronic Obstructive Pulmonary Disease and Lung Cancer: A Meta-Analysis of Risk Association
Evaluating the association between chronic obstructive pulmonary disease and the risk of developing lung cancer. Read more