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TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation
TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation
Subarachnoid hemorrhage (SAH) is associated with high mortality and disability rates, and secondary white matter injury is...
FoxG1 as a Potential Therapeutic Target for Alzheimer’s Disease: Modulating NLRP3 Inflammasome via AMPK/mTOR Autophagy Pathway
FoxG1 as a Potential Therapeutic Target for Alzheimer’s Disease: Modulating NLRP3 Inflammasome via AMPK/mTOR Autophagy Pathway
An increasing body of research suggests that promoting microglial autophagy hinders the neuroinflammation initiated though...
Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway
Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway
Surgical brain injury (SBI), induced by neurosurgical procedures or instruments, has not attracted adequate attention. The...
Correction: Inhibition of mTOR Alleviates Early Brain Injury After Subarachnoid Hemorrhage Via Relieving Excessive Mitochondrial Fission
Correction: Inhibition of mTOR Alleviates Early Brain Injury After Subarachnoid Hemorrhage Via Relieving Excessive Mitochondrial Fission
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Correction: Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil
Correction: Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Inhibition of UHRF1 Improves Motor Function in Mice with Spinal Cord Injury
Inhibition of UHRF1 Improves Motor Function in Mice with Spinal Cord Injury
Spinal-cord injury (SCI) is a severe condition that can lead to limb paralysis and motor dysfunction, and its pathogenesis...
Correction: GPR18 Agonist Resolvin D2 Reduces Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage by Multiple Protective Mechanisms
Correction: GPR18 Agonist Resolvin D2 Reduces Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage by Multiple Protective Mechanisms
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Association of Cadherin-Related Family Member 1 with Traumatic Brain Injury
Association of Cadherin-Related Family Member 1 with Traumatic Brain Injury
The cadherin family plays a pivotal role in orchestrating synapse formation in the central nervous system. Cadherin-relate...
Enhanced Spine Stability and Survival Lead to Increases in Dendritic Spine Density as an Early Response to Local Alpha-Synuclein Overexpression in Mouse Prefrontal Cortex
Enhanced Spine Stability and Survival Lead to Increases in Dendritic Spine Density as an Early Response to Local Alpha-Synuclein Overexpression in Mouse Prefrontal Cortex
Lewy Body Dementias (LBD), including Parkinson’s disease dementia and Dementia with Lewy Bodies, are characterized b...
The Efficacy of Different Material Scaffold-Guided Cell Transplantation in the Treatment of Spinal Cord Injury in Rats: A Systematic Review and Network Meta-analysis
The Efficacy of Different Material Scaffold-Guided Cell Transplantation in the Treatment of Spinal Cord Injury in Rats: A Systematic Review and Network Meta-analysis
Cell transplantation is a promising treatment option for spinal cord injury (SCI). However, there is no consensus on the c...
Stem Cell-Derived Exosomal MicroRNAs as Novel Potential Approach for Multiple Sclerosis Treatment
Stem Cell-Derived Exosomal MicroRNAs as Novel Potential Approach for Multiple Sclerosis Treatment
Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by inflammation and dem...
Correction: CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4
Correction: CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
The Role of Beta2-Microglobulin in Central Nervous System Disease
The Role of Beta2-Microglobulin in Central Nervous System Disease
Central nervous system (CNS) disorders represent the leading cause of disability and the second leading cause of death wor...
A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy
A Pharmacogenomics-Based In Silico Investigation of Opioid Prescribing in Post-operative Spine Pain Management and Personalized Therapy
Considering the variability in individual responses to opioids and the growing concerns about opioid addiction, prescribin...
Astrocyte-Specific Inhibition of the Primary Cilium Suppresses C3 Expression in Reactive Astrocyte
Astrocyte-Specific Inhibition of the Primary Cilium Suppresses C3 Expression in Reactive Astrocyte
C3-positive reactive astrocytes play a neurotoxic role in various neurodegenerative diseases. However, the mechanisms cont...
Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia–Reperfusion Injury in Rats
Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia–Reperfusion Injury in Rats
Mild hypothermia (MH) is an effective measure to alleviate cerebral ischemia–reperfusion (I/R) injury. However, the ...
A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023
A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023
In recent years, spatial transcriptomics (ST) research has become a popular field of study and has shown great potential i...
Pharmacological Modulation of the Cytosolic Oscillator Affects Glioblastoma Cell Biology
Pharmacological Modulation of the Cytosolic Oscillator Affects Glioblastoma Cell Biology
The circadian system is a conserved time-keeping machinery that regulates a wide range of processes such as sleep/wake, fe...
Patch-seq: Advances and Biological Applications
Patch-seq: Advances and Biological Applications
Multimodal analysis of gene-expression patterns, electrophysiological properties, and morphological phenotypes at the sing...
Liposome-Mediated Anti-Viral Drug Delivery Across Blood–Brain Barrier: Can Lipid Droplet Target Be Game Changers?
Liposome-Mediated Anti-Viral Drug Delivery Across Blood–Brain Barrier: Can Lipid Droplet Target Be Game Changers?
Lipid droplets (LDs) are subcellular organelles secreted from the endoplasmic reticulum (ER) that play a major role in lip...
Zika Virus Infection Alters the Circadian Clock Expression in Human Neuronal Monolayer and Neurosphere Cultures
Zika Virus Infection Alters the Circadian Clock Expression in Human Neuronal Monolayer and Neurosphere Cultures
Rhythmic regulations are virtually described in all physiological processes, including central nervous system development ...
Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell Pathophysiology
Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell Pathophysiology
Intracranial vascular malformations manifest on a continuum ranging from predominantly arterial to predominantly venous in...
Roles of Macrophages and Their Interactions with Schwann Cells After Peripheral Nerve Injury
Roles of Macrophages and Their Interactions with Schwann Cells After Peripheral Nerve Injury
The adult peripheral nervous system has a significant ability for regeneration compared to the central nervous system. Thi...
Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network
Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network
Gliomas, including anaplastic gliomas (AG; grade 3) and glioblastomas (GBM; grade 4), are malignant brain tumors associate...
Enlarged Perivascular Space and Index for Diffusivity Along the Perivascular Space as Emerging Neuroimaging Biomarkers of Neurological Diseases
Enlarged Perivascular Space and Index for Diffusivity Along the Perivascular Space as Emerging Neuroimaging Biomarkers of Neurological Diseases
The existence of lymphatic vessels or similar clearance systems in the central nervous system (CNS) that transport nutrien...
Analysis and Regulatory Mechanisms of Platelet-Related Genes in Patients with Ischemic Stroke
Analysis and Regulatory Mechanisms of Platelet-Related Genes in Patients with Ischemic Stroke
It was found that ischemic stroke (IS) was associated with abnormal platelet activity and thrombosis. However, the potenti...
CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients
CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients
Circular RNA circSKA3 (spindle and kinetochore-related complex subunit 3) has been identified as a prognostic factor in is...
Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling
Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling
Exercise can promote adult neurogenesis and improve symptoms associated with schizophrenia and other mental disorders via ...
Neonatal IL-4 Over-Exposure is Accompanied by Macrophage Accumulation in Dura Mater After Instant Anti-inflammatory Cytokine Response in CSF
Neonatal IL-4 Over-Exposure is Accompanied by Macrophage Accumulation in Dura Mater After Instant Anti-inflammatory Cytokine Response in CSF
Multiple studies have shown that clinical events resulting into neonatal IL-4 over-exposure, such as asthma in early life ...
Characterization of Retinal VIP-Amacrine Cell Development During the Critical Period
Characterization of Retinal VIP-Amacrine Cell Development During the Critical Period
Retinal vasoactive intestinal peptide amacrine cells (VIP-ACs) play an important role in various retinal light-mediated pa...
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