Adams HP Jr, Bendixen BH, Kappelle LJ et al (1993) Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in acute stroke treatment. Stroke 24:35–41. https://doi.org/10.1161/01.str.24.1.35

Article  PubMed  Google Scholar 

Adams HP Jr, Davis PH, Leira EC et al (1999) Baseline NIH stroke scale score strongly predicts outcome after stroke: a report of the trial of Org 10172 in acute stroke treatment (TOAST). Neurology 53:126–131. https://doi.org/10.1212/wnl.53.1.126

Article  PubMed  CAS  Google Scholar 

Aili Y, Maimaitiming N, Mahemuti Y et al (2021) The role of exosomal miRNAs in glioma: biological function and clinical application. Front Oncol 11:686369. https://doi.org/10.3389/fonc.2021.686369

Article  PubMed  PubMed Central  CAS  Google Scholar 

Aimaletdinov AM, Gomzikova MO (2022) Tracking of extracellular vesicles’ biodistribution: new methods and approaches. Int J Mol Sci. https://doi.org/10.3390/ijms231911312

Article  PubMed  PubMed Central  Google Scholar 

Alexander M, Hu R, Runtsch MC et al (2015) Exosome-delivered microRNAs modulate the inflammatory response to endotoxin. Nat Commun 6:7321. https://doi.org/10.1038/ncomms8321

Article  PubMed  CAS  Google Scholar 

Al-Onaizi M, Al-Khalifah A, Qasem D, ElAli A (2020) Role of microglia in modulating adult neurogenesis in health and neurodegeneration. Int J Mol Sci. https://doi.org/10.3390/ijms21186875

Article  PubMed  PubMed Central  Google Scholar 

Araki T, Ikegaya Y, Koyama R (2021) The effects of microglia- and astrocyte-derived factors on neurogenesis in health and disease. Eur J Neurosci 54:5880–5901. https://doi.org/10.1111/ejn.14969

Article  PubMed  CAS  Google Scholar 

Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297. https://doi.org/10.1016/s0092-8674(04)00045-5

Article  PubMed  CAS  Google Scholar 

Bidzhekov K, Gan L, Denecke B et al (2012) microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans. Thromb Haemost 107:619–625. https://doi.org/10.1160/TH11-09-0607

Article  PubMed  CAS  Google Scholar 

Camussi G, Deregibus MC, Bruno S et al (2010) Exosomes/microvesicles as a mechanism of cell-to-cell communication. Kidney Int 78:838–848. https://doi.org/10.1038/ki.2010.278

Article  PubMed  CAS  Google Scholar 

Castrén E, Antila H (2017) Neuronal plasticity and neurotrophic factors in drug responses. Mol Psychiatry 22:1085–1095. https://doi.org/10.1038/mp.2017.61

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chaudhuri AA, So AY-L, Sinha N et al (2011) MicroRNA-125b potentiates macrophage activation. J Immunol 187:5062–5068. https://doi.org/10.4049/jimmunol.1102001

Article  PubMed  CAS  Google Scholar 

Chen Y, Song Y, Huang J et al (2017) Increased circulating exosomal miRNA-223 is associated with acute ischemic stroke. Front Neurol 8:57. https://doi.org/10.3389/fneur.2017.00057

Article  PubMed  PubMed Central  Google Scholar 

Chen Q, Liu Y, Ding X et al (2020) Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7. Mol Cell Biochem 465:103–114. https://doi.org/10.1007/s11010-019-03671-z

Article  PubMed  CAS  Google Scholar 

Cui J, Liu N, Chang Z et al (2020) Exosomal MicroRNA-126 from RIPC serum is involved in hypoxia tolerance in SH-SY5Y cells by downregulating DNMT3B. Mol Ther Nucleic Acids 20:649–660. https://doi.org/10.1016/j.omtn.2020.04.008

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cun Y, Jin Y, Wu D et al (2022) Exosome in crosstalk between inflammation and angiogenesis: a potential therapeutic strategy for stroke. Mediators Inflamm 2022:7006281. https://doi.org/10.1155/2022/7006281

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cuomo O, Anzilotti S, Brancaccio P et al (2024) Systemic administration of blood-derived exosomes induced by remote ischemic post-conditioning, by delivering a specific cluster of miRNAs, ameliorates ischemic damage and neurological function. J Cereb Blood Flow Metab 44:1459–1471. https://doi.org/10.1177/0271678X241270284

Article  PubMed  CAS  Google Scholar 

Czajka P, Fitas A, Jakubik D et al (2021) MicroRNA as potential biomarkers of platelet function on antiplatelet therapy: a review. Front Physiol 12:652579. https://doi.org/10.3389/fphys.2021.652579

Article  PubMed  PubMed Central  Google Scholar 

El-Khazragy N, Noshi MA, Abdel-Malak C et al (2019) miRNA-155 and miRNA-181a as prognostic biomarkers for pediatric acute lymphoblastic leukemia. J Cell Biochem 120:6315–6321. https://doi.org/10.1002/jcb.27918

Article  PubMed  CAS  Google Scholar 

Eyileten C, Kaplon-Cieslicka A, Mirowska-Guzel D et al (2017) Antidiabetic effect of brain-derived neurotrophic factor and its association with inflammation in type 2 diabetes mellitus. J Diabetes Res 2017:2823671. https://doi.org/10.1155/2017/2823671

Article  PubMed  PubMed Central  CAS  Google Scholar 

Eyileten C, Sharif L, Wicik Z et al (2021) The relation of the brain-derived neurotrophic factor with MicroRNAs in neurodegenerative diseases and ischemic stroke. Mol Neurobiol 58:329–347. https://doi.org/10.1007/s12035-020-02101-2

Article  PubMed  Google Scholar 

Eyileten C, Jakubik D, Shahzadi A et al (2022a) Diagnostic performance of circulating miRNAs and extracellular vesicles in acute ischemic stroke. Int J Mol Sci. https://doi.org/10.3390/ijms23094530

Article  PubMed  PubMed Central  Google Scholar 

Eyileten C, Wicik Z, Keshwani D et al (2022b) Alteration of circulating platelet-related and diabetes-related microRNAs in individuals with type 2 diabetes mellitus: a stepwise hypoglycaemic clamp study. Cardiovasc Diabetol 21:79. https://doi.org/10.1186/s12933-022-01517-5

Article  PubMed  PubMed Central  CAS  Google Scholar 

Fu L-L, Wen X, Bao J-K, Liu B (2012) MicroRNA-modulated autophagic signaling networks in cancer. Int J Biochem Cell Biol 44:733–736. https://doi.org/10.1016/j.biocel.2012.02.004

Article  PubMed  CAS  Google Scholar 

Gao F, Chang J, Wang H, Zhang G (2014) Potential diagnostic value of miR-155 in serum from lung adenocarcinoma patients. Oncol Rep 31:351–357. https://doi.org/10.3892/or.2013.2830

Article  PubMed  CAS  Google Scholar 

Gao L, Zhang Y, Sterling K, Song W (2022) Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential. Transl Neurodegener 11:4. https://doi.org/10.1186/s40035-022-00279-0

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gao C, Jiang J, Tan Y, Chen S (2023) Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal Transduct Target Ther 8:359. https://doi.org/10.1038/s41392-023-01588-0

Article  PubMed  PubMed Central  Google Scholar 

Ge Q, Zhou Y, Lu J et al (2014) miRNA in plasma exosome is stable under different storage conditions. Molecules 19:1568–1575. https://doi.org/10.3390/molecules19021568

Article  PubMed  PubMed Central