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Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence
Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence
The 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT, known online as “Moxy”) is a new psychedelic tryptam...
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state
Alzheimer’s disease (AD) is characterized by the loss of memory due to aggregation of misphosphorylated tau and amyl...
Perspectives of healthcare workers on the integration of overdose detection technologies in acute care settings
Perspectives of healthcare workers on the integration of overdose detection technologies in acute care settings
People who use drugs (PWUD) face disproportionately high rates of hospitalizations and patient-initiated discharge (leavin...
Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity
Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity
Variability in genes involved in drug pharmacokinetics or drug response can be responsible for suboptimal treatment effica...
The acceptability of lifestyle medicine for the treatment of mental illness: perspectives of people with and without lived experience of mental illness
The acceptability of lifestyle medicine for the treatment of mental illness: perspectives of people with and without lived experience of mental illness
While lifestyle medicine can be highly effective for treating a range of mental illnesses these approaches are grossly und...
The impact of the COVID-19 pandemic on rates of adolescents receiving psychopharmacological medication in Austria
The impact of the COVID-19 pandemic on rates of adolescents receiving psychopharmacological medication in Austria
The COVID-19 pandemic has impacted many aspects of everyday life, including the (mental) healthcare system. An increase in...
PPI in psychiatry and the problem of knowledge
PPI in psychiatry and the problem of knowledge
This article begins by locating Patient and Public involvement ((PPI) historically and argues that ‘mental health...
Recovery-orientierte Behandlung und Genesungsbegleitung in der Psychiatrie
Recovery-orientierte Behandlung und Genesungsbegleitung in der Psychiatrie
Der Begriff Recovery ist national und international in der Versorgung psychisch erkrankter Menschen inzwischen fest etabli...
Aripiprazole and its adverse effects in the form of impulsive-compulsive behaviors: A systematic review of case reports
Aripiprazole and its adverse effects in the form of impulsive-compulsive behaviors: A systematic review of case reports
Aripiprazole is an efficacious treatment for both the positive and negative symptoms of schizophrenia and is also commonly...
Why is lithium [not] the drug of choice for bipolar disorder? a controversy between science and clinical practice
Why is lithium [not] the drug of choice for bipolar disorder? a controversy between science and clinical practice
During over half a century, science has shown that lithium is the most efficacious treatment for bipolar...
On mental pain and suicide risk in modern psychiatry
On mental pain and suicide risk in modern psychiatry
Facing suicide risk is probably the most difficult task for clinicians when dealing with patients in crisis. It requires p...
Biomarkers for neurodegeneration impact cognitive function: a longitudinal 1-year case–control study of patients with bipolar disorder and healthy control individuals
Biomarkers for neurodegeneration impact cognitive function: a longitudinal 1-year case–control study of patients with bipolar disorder and healthy control individuals
Abnormalities in cerebrospinal fluid (CSF)-amyloid-beta (Aβ)42, CSF-Aβ40, CSF-Aβ38, CSF-soluble amyloid pre...
How to embrace transdiagnostic concepts when neurodevelopmental disorders become harbingers of adult psychopathology?
How to embrace transdiagnostic concepts when neurodevelopmental disorders become harbingers of adult psychopathology?
Neurodevelopmental disorders are less prevalent than adult-onset mental health issues...
Lifetime risk of severe kidney disease in lithium-treated patients: a retrospective study
Lifetime risk of severe kidney disease in lithium-treated patients: a retrospective study
Lithium is an essential psychopharmaceutical, yet side effects and concerns about severe renal function impairment limit i...
Neurobiology
Neurobiology
This volume will serve as a guide for students in the field of neurobiology, and be a bridge between basic science researc...
Beyond Psychopharmacology: the Interpersonal Dynamics of Agitation Management
Beyond Psychopharmacology: the Interpersonal Dynamics of Agitation Management
Schwartz TL, Park TL. Assaults by patients on psychiatric residents: a survey and training recommendations. Psychiatr Serv...
Ketamine produces no detectable long-term positive or negative effects on cognitive flexibility or reinforcement learning of male rats
Ketamine produces no detectable long-term positive or negative effects on cognitive flexibility or reinforcement learning of male rats
Patients with major depressive disorder (MDD) often experience abnormalities in behavioral adaptation following environmen...
Evaluation and management of insomnia in the clinical practice in Italy: a 2023 update from the Insomnia Expert Consensus Group
Evaluation and management of insomnia in the clinical practice in Italy: a 2023 update from the Insomnia Expert Consensus Group
Insomnia is the most reported sleep disorder in industrialized countries, affecting, in the chronic form, around 10% of th...
Factors associated with suicide attempts in the antecedent illness trajectory of bipolar disorder and schizophrenia
Factors associated with suicide attempts in the antecedent illness trajectory of bipolar disorder and schizophrenia
Factors associated with suicide attempts during the antecedent illness trajectory of bipolar disorder (BD) and schizophren...
Attitudes of Swiss psychiatrists towards cannabis regulation and medical use in psychiatry: a cross-sectional study
Attitudes of Swiss psychiatrists towards cannabis regulation and medical use in psychiatry: a cross-sectional study
Changes in regulation for cannabis for nonmedical use (CNMU) are underway worldwide. Switzerland amended the law in 2021 a...
Early life social complexity shapes adult neural processing in the communal spiny mouse Acomys cahirinus
Early life social complexity shapes adult neural processing in the communal spiny mouse Acomys cahirinus
Early life social rearing has profound consequences on offspring behavior and resilience. Yet, most studies examining earl...
Meningeosis neoplastica als Differenzialdiagnose einer rasch progredienten Demenz
Meningeosis neoplastica als Differenzialdiagnose einer rasch progredienten Demenz
kbo-Inn-Salzach-Klinikum, Fachkrankenhaus für Psychiatrie, Psychotherapie, Psychosomatische Medizin, Geriatrie und Neurolo...
Facts and myths about the use of lithium for bipolar disorder in routine clinical practice: an expert consensus paper
Facts and myths about the use of lithium for bipolar disorder in routine clinical practice: an expert consensus paper
Bipolar disorder is one of the most burdensome severe mental disorders, characterized by high levels of personal and socia...
Clinical characteristics of suicidal behavior in first hospitalization and drug-naïve patients with major depressive disorder
Clinical characteristics of suicidal behavior in first hospitalization and drug-naïve patients with major depressive disorder
Major depressive disorder (MDD) is a major and common cause of suicide. The purpose of this article is to report the clini...
Cognitive Behavioral Therapy in an Adolescent with Juvenile Ankylosing Spondylitis: a Case Study
Cognitive Behavioral Therapy in an Adolescent with Juvenile Ankylosing Spondylitis: a Case Study
Juvenile ankylosing spondylitis (JAS) is a systemic inflammatory arthritis that can negatively impact quality of life and ...
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
Problematic alcohol use (PAU), a trait that combines alcohol use disorder and alcohol-related problems assessed with a que...
Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms
Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms
Ketamine is an open channel blocker of ionotropic glutamatergic N-Methyl-D-Aspartate (NMDA) receptors. The discovery of it...
The Art of Healing in Correctional Psychiatry
The Art of Healing in Correctional Psychiatry
Coming out of residency, I knew I wanted to work in correctional psychiatry. Jail...
Effects of cannabidiol on fear conditioning in anxiety disorders: decreased threat expectation during retention, but no enhanced fear re-extinction
Effects of cannabidiol on fear conditioning in anxiety disorders: decreased threat expectation during retention, but no enhanced fear re-extinction
Preclinical research suggests that pharmacologically elevating cannabinoid levels may attenuate fear memory expression and...
VR-gestützte Therapie bei Angst und posttraumatischer Belastungsstörung: aktuelle Möglichkeiten und Grenzen
VR-gestützte Therapie bei Angst und posttraumatischer Belastungsstörung: aktuelle Möglichkeiten und Grenzen
Virtuelle Realität (VR) wird zunehmend in der Psychotherapie eingesetzt, dabei nimmt das Entwicklungstempo von VR-The...
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