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Indoleamine 2,3-Dioxygenase-1 Expression is Changed During Bladder Cancer Cell Invasion
Indoleamine 2,3-Dioxygenase-1 Expression is Changed During Bladder Cancer Cell Invasion
The severity of the bladder carcinoma (BC) is directly linked to cell invasion and metastasis. Indoleamine 2,3-dioxygenase...
Differential Effect of Non-Purified and Semi-Purified Standard Diets on Kynurenine and Peripheral Metabolites in Male C57BL/6J Mice
Differential Effect of Non-Purified and Semi-Purified Standard Diets on Kynurenine and Peripheral Metabolites in Male C57BL/6J Mice
The kynurenine (Kyn) pathway plays crucial roles in several inflammation-induced disorders such as depression. In this stu...
Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site
Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site
Protein dynamics governs most of the fundamental processes in the human body. Particularly, the dynamics of loops located ...
Does Exercise Influence Kynurenine/Tryptophan Metabolism and Psychological Outcomes in Persons With Age-Related Diseases? A Systematic Review
Does Exercise Influence Kynurenine/Tryptophan Metabolism and Psychological Outcomes in Persons With Age-Related Diseases? A Systematic Review
Background:The kynurenine (KYN) pathway has been implicated in many diseases associated with inflammation and aging (“infl...
Lack of Skeletal Muscle Serotonin Impairs Physical Performance
Lack of Skeletal Muscle Serotonin Impairs Physical Performance
Low levels of the neurotransmitter serotonin have been associated with the onset of depression. While traditional treatmen...
Effects of Psychological and Physical Stress on Oxidative Stress, Serotonin, and Fatigue in Young Females Induced by Objective Structured Clinical Examination: Pilot Study of u-8-OHdG, u-5HT, and s-HHV-6
Effects of Psychological and Physical Stress on Oxidative Stress, Serotonin, and Fatigue in Young Females Induced by Objective Structured Clinical Examination: Pilot Study of u-8-OHdG, u-5HT, and s-HHV-6
Background:To establish a method to prevent and manage fatigue caused by psychological and physical stress in young female...
An Investigation into the Temporal Reproducibility of Tryptophan Metabolite Networks Among Healthy Adolescents
An Investigation into the Temporal Reproducibility of Tryptophan Metabolite Networks Among Healthy Adolescents
Tryptophan and its bioactive metabolites are associated with health conditions such as systemic inflammation, cardiometabo...
Blockade of KAT II Facilitates LTP in Kynurenine 3-Monooxygenase Depleted Mice
Blockade of KAT II Facilitates LTP in Kynurenine 3-Monooxygenase Depleted Mice
Excess of brain kynurenic acid (KYNA), a neuroactive metabolite of the kynurenine pathway, is known to elicit cognitive dy...
Neurotransmitter Precursor Amino Acid Ratios Show Differential, Inverse Correlations with Depression Severity in the Low and High Depression Score Range
Neurotransmitter Precursor Amino Acid Ratios Show Differential, Inverse Correlations with Depression Severity in the Low and High Depression Score Range
The immunomodulatory capacity of mental stress is one of the basic concepts of psychoneuroimmunology. The current prospect...
Improved Voltammetric Determination of Kynurenine at the Nafion Covered Glassy Carbon Electrode – Application in Samples Delivered from Human Cancer Cells
Improved Voltammetric Determination of Kynurenine at the Nafion Covered Glassy Carbon Electrode – Application in Samples Delivered from Human Cancer Cells
Nowadays, development of analytical methods responding to a need for rapid and accurate determination of human metabolites...
The Effects of Maternal Interleukin-17A on Social Behavior, Cognitive Function, and Depression-Like Behavior in Mice with Altered Kynurenine Metabolites
The Effects of Maternal Interleukin-17A on Social Behavior, Cognitive Function, and Depression-Like Behavior in Mice with Altered Kynurenine Metabolites
Viral infection and chronic maternal inflammation during pregnancy are correlated with a higher prevalence of autism spect...
Plasma Anthranilic Acid and Leptin Levels Predict HAM-D Scores in Depressed Women
Plasma Anthranilic Acid and Leptin Levels Predict HAM-D Scores in Depressed Women
Objectives:Major depressive disorder (MDD) is associated with dysregulations of leptin and tryptophan–kynurenine (Trp–Kyn)...
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