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High-dose glucocorticoids in COVID-19 patients with acute encephalopathy: clinical and imaging findings in a retrospective cohort study
High-dose glucocorticoids in COVID-19 patients with acute encephalopathy: clinical and imaging findings in a retrospective cohort study
Acute encephalopathy (AE) has been described as a severe complication of COVID-19. Inflammation has been suggested as a pa...
Combined light and electron microscopy (CLEM) to quantify methamphetamine-induced alpha-synuclein-related pathology
Combined light and electron microscopy (CLEM) to quantify methamphetamine-induced alpha-synuclein-related pathology
Methamphetamine (METH) produces a cytopathology, which is rather specific within catecholamine neurons both in vitro and e...
Does thyroid diseases contribute to the natural history of idiopathic adult-onset dystonia? Data from the Italian Dystonia Registry
Does thyroid diseases contribute to the natural history of idiopathic adult-onset dystonia? Data from the Italian Dystonia Registry
A few earlier observations and recent controlled studies pointed to the possible contribution of thyroid diseases in idiop...
It is not just about transcription: involvement of brain RNA splicing in substance use disorders
It is not just about transcription: involvement of brain RNA splicing in substance use disorders
Alternative splicing is a co-transcriptional process that significantly contributes to the molecular landscape of the cell...
Impaired dual-task gait in Parkinson’s disease is associated with brain morphology changes
Impaired dual-task gait in Parkinson’s disease is associated with brain morphology changes
In Parkinson’s disease (PD), impaired gait and cognition affect daily activities, particularly in the more advanced ...
Headache patterns in patent foramen ovale patients: beyond migraine with aura
Headache patterns in patent foramen ovale patients: beyond migraine with aura
Patent foramen ovale (PFO) is a common cardiac anomaly linked with cryptogenic strokes and migraine, particularly migraine...
NFKB1 variants were associated with the risk of Parkinson´s disease in male
NFKB1 variants were associated with the risk of Parkinson´s disease in male
The NF-κB pathway is involved in the pathogenesis of neurological disorders that have inflammation as a hallmark, inc...
More than fear? Brain activation patterns of dental phobic patients before and after an exposure-based treatment
More than fear? Brain activation patterns of dental phobic patients before and after an exposure-based treatment
Hyperactivation of brain networks conferring defensive mobilization is assumed to underlie inappropriate defensive-prepara...
Morphometric alterations of the mesocorticolimbic network in Parkinson’s disease with impulse control disorders
Morphometric alterations of the mesocorticolimbic network in Parkinson’s disease with impulse control disorders
Impulse control disorders (ICDs) are a group of non-motor symptoms of Parkinson disease (PD) leading to significant psycho...
Edema related to treatment with psychotropic drugs
Edema related to treatment with psychotropic drugs
Edema as an adverse drug reaction is a commonly underestimated yet potentially debilitating condition. This study analyzes...
The natural course of idiopathic cervical dystonia
The natural course of idiopathic cervical dystonia
Idiopathic cervical dystonia (ICD) is by far the largest subgroup of dystonia. Still, its natural course is largely unknow...
Modulatory effect of olanzapine on neuronal nitric oxide synthase (nNOS) expression in the rat striatum
Modulatory effect of olanzapine on neuronal nitric oxide synthase (nNOS) expression in the rat striatum
Nitric oxide (NO) has been thought to be a novel factor involved in the mechanisms of mental disorders pathogenesis for qu...
Parkinson’s disease motor progression in relation to the timing of REM sleep behavior disorder presentation: an exploratory retrospective study
Parkinson’s disease motor progression in relation to the timing of REM sleep behavior disorder presentation: an exploratory retrospective study
REM sleep behavior disorder (RBD) is a frequent non-motor symptom of Parkinson’s disease (PD), and the timing of its...
Oxidation of dopamine and related catechols in dopaminergic brain regions in Parkinson’s disease and during ageing in non-Parkinsonian subjects
Oxidation of dopamine and related catechols in dopaminergic brain regions in Parkinson’s disease and during ageing in non-Parkinsonian subjects
The present study was performed to examine if catechol oxidation is higher in brains from patients with Parkinson’s ...
Obsessive–compulsive symptoms and brain lesions compatible with multiple sclerosis
Obsessive–compulsive symptoms and brain lesions compatible with multiple sclerosis
Autoimmune-mediated obsessive–compulsive disorder (OCD) can occur in multiple sclerosis (MS). Here, a well-studied c...
Differential patterns of functional connectivity in tremor dominant Parkinson’s disease and essential tremor plus
Differential patterns of functional connectivity in tremor dominant Parkinson’s disease and essential tremor plus
Tremor dominant Parkinson’s disease (TDPD) and essential tremor plus (ETP) syndrome are commonly encountered tremor ...
Neurogenic orthostatic hypotension in Parkinson’s disease: is there a role for locus coeruleus magnetic resonance imaging?
Neurogenic orthostatic hypotension in Parkinson’s disease: is there a role for locus coeruleus magnetic resonance imaging?
Locus coeruleus (LC) is the main noradrenergic nucleus of the brain, and degenerates early in Parkinson’s disease (P...
Rewiring the future: drugs abused in adolescence may predispose to mental illness in adult life by altering dopamine axon growth
Rewiring the future: drugs abused in adolescence may predispose to mental illness in adult life by altering dopamine axon growth
Adolescence is a period of increased exploration and novelty-seeking, which includes new social behaviors, as well as drug...
Therapeutic use of medical Cannabis in neurological diseases: a clinical update
Therapeutic use of medical Cannabis in neurological diseases: a clinical update
The use of medical Cannabis has increased in recent years due to changing legal circumstances in many countries. Approval ...
Psychotherapies in opioid use disorder: toward a step-care model
Psychotherapies in opioid use disorder: toward a step-care model
Opioid use disorder (OUD) is characterized by a lack of control in opioid use, resulting in psychological distress and def...
Abstracts of the WASAD Congress 2023: an International Congress of the World Association for Stress Related and Anxiety Disorders, held on 11–13 September 2023 in Zurich, Switzerland
Abstracts of the WASAD Congress 2023: an International Congress of the World Association for Stress Related and Anxiety Disorders, held on 11–13 September 2023 in Zurich, Switzerland
Cite this article Abstracts of the WASAD Congress 2023: an International Congress of the World Association for Stress Rela...
Should continuous dopaminergic stimulation be a standard of care in advanced Parkinson’s disease?
Should continuous dopaminergic stimulation be a standard of care in advanced Parkinson’s disease?
The standard of care is a term that refers to the level of care, skill, and treatment that a healthcare provider should of...
Understanding depression with amyotrophic lateral sclerosis: a short assessment of facts and perceptions
Understanding depression with amyotrophic lateral sclerosis: a short assessment of facts and perceptions
Depression with an average prevalence of 25–40% is a serious condition in amyotrophic lateral sclerosis (ALS) that c...
Baseline prevalence and longitudinal assessment of autonomic dysfunction in early Parkinson’s disease
Baseline prevalence and longitudinal assessment of autonomic dysfunction in early Parkinson’s disease
Autonomic dysfunction (AutD) is common and debilitating in Parkinson’s disease (PD). Predictors of AutD are unclear,...
Astrocytic transcriptional and epigenetic mechanisms of drug addiction
Astrocytic transcriptional and epigenetic mechanisms of drug addiction
Addiction is a leading cause of disease burden worldwide and remains a challenge in current neuroscience research. Drug-in...
Levodopa may modulate specific speech impairment in Parkinson's disease: an fMRI study
Levodopa may modulate specific speech impairment in Parkinson's disease: an fMRI study
Hypokinetic dysarthria (HD) is a difficult-to-treat symptom affecting quality of life in patients with Parkinson’s d...
Neuroscience in addiction research
Neuroscience in addiction research
The prevention and treatment of addiction (moderate to severe substance use disorder—SUD) have remained challenging ...
Home initiation of apomorphine infusion: lessons from the COVID-19 pandemic and implications for current clinical practice
Home initiation of apomorphine infusion: lessons from the COVID-19 pandemic and implications for current clinical practice
Starting Parkinson’s disease (PD) patients on subcutaneous apomorphine (APO) infusion is generally undertaken on a h...
The role of immune and inflammatory-related indicators in cognitive dysfunction and disease severity in patients with parkinson’s disease
The role of immune and inflammatory-related indicators in cognitive dysfunction and disease severity in patients with parkinson’s disease
We aimed to explore the role of immune and inflammatory indicators in cognitive dysfunction and disease severity in patien...
The specific NQO2 inhibitor, S29434, only marginally improves the survival of dopamine neurons in MPTP-intoxicated mice
The specific NQO2 inhibitor, S29434, only marginally improves the survival of dopamine neurons in MPTP-intoxicated mice
Over the years, evidence has accumulated on a possible contributive role of the cytosolic quinone reductase NQO2 in models...
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