Andreu-Cervera A, Anselme I, Karam A, Laclef C, Catala M, Schneider-Maunoury S (2019) The ciliopathy gene ftm/rpgrip1l controls mouse forebrain patterning via region-specific modulation of Hedgehog/Gli signaling. J Neurosci 39:2398–2415
PubMed PubMed Central Google Scholar
Arioli M, Cattaneo Z, Rusconi ML, Blandini F, Tettamanti M (2022) Action and emotion perception in Parkinson’s disease: a neuroimaging meta-analysis. NeuroImage Clin 35:103031
Article PubMed PubMed Central Google Scholar
Arts HH, Doherty D, van Beersum SE, Parisi MA, Letteboer SJ, Gorden NT, Peters TA, Märker T, Voesenek K, Kartono A, Ozyurek H, Farin FM, Kroes HY, Wolfrum U, Brunner HG, Cremers FP, Glass IA, Knoers NV, Roepman R (2007) Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome. Nat Genet 39:882–888
Article CAS PubMed Google Scholar
Bai B et al (2020) Deep multilayer brain proteomics identifies molecular networks in Alzheimer’s disease progression. Neuron 105:975-991.e977
Article CAS PubMed PubMed Central Google Scholar
Birey F, Li MY, Gordon A, Thete MV, Valencia AM, Revah O, Paşca AM, Geschwind DH, Paşca SP (2022) Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome. Cell Stem Cell 29:248-264.e247
Article CAS PubMed Google Scholar
Chen K, Gunter K, Maines MD (2000) Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death. J Neurochem 75:304–313
Article CAS PubMed Google Scholar
Cheng J, Li F, Sun X, Liu S, Chen L, Tian F, Zhao Z, Hu H, Li X (2020) Low-dose alcohol ameliorated homocysteine-induced anxiety-related behavior via attenuating oxidative stress in mice. Neurosci Lett 714:134568
Article CAS PubMed Google Scholar
Cryan JF, Mombereau C, Vassout A (2005) The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev 29:571–625
Article CAS PubMed Google Scholar
D’Adamo MC, Liantonio A, Conte E, Pessia M, Imbrici P (2020) Ion channels involvement in neurodevelopmental disorders. Neuroscience 440:337–359
Article CAS PubMed Google Scholar
Delous M et al (2007) The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome. Nat Genet 39:875–881
Article CAS PubMed Google Scholar
Evdokimov E, Sharma P, Lockett SJ, Lualdi M, Kuehn MR (2008) Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3. J Cell Sci 121:4106–4113
Article CAS PubMed Google Scholar
Feligioni M, Nishimune A, Henley JM (2009) Protein SUMOylation modulates calcium influx and glutamate release from presynaptic terminals. Eur J Neurosci 29:1348–1356
Article PubMed PubMed Central Google Scholar
Foran E, Rosenblum L, Bogush A, Pasinelli P, Trotti D (2014) Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization. Glia 62:1241–1253
Article CAS PubMed PubMed Central Google Scholar
Gonzales MM, Garbarino VR, Pollet E, Palavicini JP, Kellogg DL, Jr., Kraig E, Orr ME (2022) Biological aging processes underlying cognitive decline and neurodegenerative disease. J Clin Investig 132
Haddad S, Ablinger C, Stanika R, Hessenberger M, Campiglio M, Ortner NJ, Tuluc P, Obermair GJ (2025) A biallelic mutation in CACNA2D2 associated with developmental and epileptic encephalopathy affects calcium channel-dependent as well as synaptic functions of α(2)δ-2. J Neurochem 169:e16197
Article CAS PubMed Google Scholar
Hay RT (2005) SUMO: a history of modification. Mol Cell 18:1–12
Article CAS PubMed Google Scholar
Hendriks IA, Vertegaal AC (2016) A comprehensive compilation of SUMO proteomics. Nat Rev Mol Cell Biol 17:581–595
Article CAS PubMed Google Scholar
Hou Y, Dan X, Babbar M, Wei Y, Hasselbalch SG, Croteau DL, Bohr VA (2019) Ageing as a risk factor for neurodegenerative disease. Nat Rev Neurol 15:565–581
Isozaki T, Komenoi S, Lu Q, Usuki T, Tomokata S, Matsutomo D, Sakai H, Bando K, Kiyonari H, Sakane F (2016) Deficiency of diacylglycerol kinase η induces lithium-sensitive mania-like behavior. J Neurochem 138:448–456
Article CAS PubMed Google Scholar
Iyer KA, Alix K, Eltit JM, Solis E Jr, Pan X, Argade MD, Khatri S, De Felice LJ, Sweet DH, Schulte MK, Dukat M (2019) Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test. Psychopharmacology 236:2093–2104
Article CAS PubMed Google Scholar
Jackson SP, Durocher D (2013) Regulation of DNA damage responses by ubiquitin and SUMO. Mol Cell 49:795–807
Article CAS PubMed Google Scholar
Karayel O, Virreira Winter S, Padmanabhan S, Kuras YI, Vu DT, Tuncali I, Merchant K, Wills AM, Scherzer CR, Mann M (2022) Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease. Cell Rep Med 3:100661
Article CAS PubMed PubMed Central Google Scholar
Kasap M, Dwyer DS (2021) Na(+) leak-current channel (NALCN) at the junction of motor and neuropsychiatric symptoms in Parkinson’s disease. J Neural Transm 128:749–762
Krumova P, Weishaupt JH (2013) Sumoylation in neurodegenerative diseases. Cell Mol Life Sci: CMLS 70:2123–2138
Article CAS PubMed Google Scholar
Lee L, Sakurai M, Matsuzaki S, Arancio O, Fraser P (2013) SUMO and Alzheimer’s disease. NeuroMol Med 15:720–736
Lindberg FA, Nordenankar K, Fredriksson R (2022) SLC38A10 knockout mice display a decreased body weight and an increased risk-taking behavior in the open field test. Front Behav Neurosci 16:840987
Article CAS PubMed PubMed Central Google Scholar
Liu Q, Xi Y, Wang Q, Liu J, Li P, Meng X, Liu K, Chen W, Liu X, Liu Z (2021) Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer’s disease mouse model via regulating the gut microbiota-brain axis. Brain Behav Immun 95:330–343
Article CAS PubMed Google Scholar
Loboda A, Jozkowicz A, Dulak J (2015) HO-1/CO system in tumor growth, angiogenesis and metabolism—targeting HO-1 as an anti-tumor therapy. Vascul Pharmacol 74:11–22
Article CAS PubMed Google Scholar
Loboda A, Damulewicz M, Pyza E, Jozkowicz A, Dulak J (2016) Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism. Cell Mol Life Sci 73:3221–3247
Article CAS PubMed PubMed Central Google Scholar
Lomelí H, Vázquez M (2011) Emerging roles of the SUMO pathway in development. Cell Mol Life Sci 68:4045–4064
Article PubMed PubMed Central Google Scholar
Nisticò R, Ferraina C, Marconi V, Blandini F, Negri L, Egebjerg J, Feligioni M (2014) Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer’s disease. Front Pharmacol 5:63
PubMed PubMed Central Google Scholar
Pentkowski NS, Rogge-Obando KK, Donaldson TN, Bouquin SJ, Clark BJ (2021) Anxiety and Alzheimer’s disease: Behavioral analysis and neural basis in rodent models of Alzheimer’s-related neuropathology. Neurosci Biobehav Rev 127:647–658
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