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Correction to: (+)-Catechin Alleviates CCI-Induced Neuropathic Pain in Rats by Modulating the IL34/CSFIR Axis and Attenuating the Schwann Cell-Macrophage Cascade Response in the DRG
Correction to: (+)-Catechin Alleviates CCI-Induced Neuropathic Pain in Rats by Modulating the IL34/CSFIR Axis and Attenuating the Schwann Cell-Macrophage Cascade Response in the DRG
Correction to: Molecular NeurobiologyThe original version of this article unfortunate...
Role of Cytoskeletal Elements in Regulation of Synaptic Functions: Implications Toward Alzheimer’s Disease and Phytochemicals-Based Interventions
Role of Cytoskeletal Elements in Regulation of Synaptic Functions: Implications Toward Alzheimer’s Disease and Phytochemicals-Based Interventions
Alzheimer’s disease (AD), a multifactorial disease, is characterized by the accumulation of neurofibrillary tangles ...
Extracellular Purine Metabolism—Potential Target in Multiple Sclerosis
Extracellular Purine Metabolism—Potential Target in Multiple Sclerosis
The purinergic signaling system comprises a complex network of extracellular purines and purine-metabolizing ectoenzymes, ...
Oxidative Stress and Migraine
Oxidative Stress and Migraine
The pathogenesis of migraine is not completely understood, but inflammation and oxidative stress seem to be involved, acco...
Relationship Between Reactive Astrocytes, by [18F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer’s Disease
Relationship Between Reactive Astrocytes, by [18F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer’s Disease
Reactive astrocytes play an important role in the development of Alzheimer’s disease (AD). Here, we aimed to investi...
High Frequency of Autoantibodies in COVID-19 Patients with Central Nervous System Complications: a Multicenter Observational Study
High Frequency of Autoantibodies in COVID-19 Patients with Central Nervous System Complications: a Multicenter Observational Study
We present a panel of central nervous system (CNS) complications associated with coronavirus disease 2019 (COVID-19) and t...
Research Advances in Neuroblast Migration in Traumatic Brain Injury
Research Advances in Neuroblast Migration in Traumatic Brain Injury
Neuroblasts were first derived from the adult mammalian brains in the 1990s by Reynolds et al. Since then, persistent neur...
LPAR6 Participates in Neuropathic Pain by Mediating Astrocyte Cells via ROCK2/NF-κB Signal Pathway
LPAR6 Participates in Neuropathic Pain by Mediating Astrocyte Cells via ROCK2/NF-κB Signal Pathway
Neuropathic pain (NPP) is a common type of chronic pain. Glial cells, including astrocytes (AS), are believed to play an i...
AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment
AQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment
Cognitive impairment is considered to be one of the important comorbidities of diabetes, but the underlying mechanisms are...
Acute Administration of HIV-1 Tat Protein Drives Glutamatergic Alterations in a Rodent Model of HIV-Associated Neurocognitive Disorders
Acute Administration of HIV-1 Tat Protein Drives Glutamatergic Alterations in a Rodent Model of HIV-Associated Neurocognitive Disorders
HIV-1-associated neurocognitive disorders (HAND) are a major comorbidity of HIV-1 infection, marked by impairment of execu...
Roles of KCNA2 in Neurological Diseases: from Physiology to Pathology
Roles of KCNA2 in Neurological Diseases: from Physiology to Pathology
Potassium voltage-gated channel subfamily a member 2 (Kv1.2, encoded by KCNA2) is highly expressed in the central and peri...
Resveratrol Ameliorates Retinal Ischemia-Reperfusion Injury by Modulating the NLRP3 Inflammasome and Keap1/Nrf2/HO-1 Signaling Pathway
Resveratrol Ameliorates Retinal Ischemia-Reperfusion Injury by Modulating the NLRP3 Inflammasome and Keap1/Nrf2/HO-1 Signaling Pathway
Glaucoma, as an ischemia-reperfusion (I/R) injury disease, leading irreversible blindness through the loss of retinal gang...
Utilizing Machine Learning to Identify Biomarkers of Endoplasmic Reticulum Stress and Analyze Immune Cell Infiltration in Parkinson’s Disease
Utilizing Machine Learning to Identify Biomarkers of Endoplasmic Reticulum Stress and Analyze Immune Cell Infiltration in Parkinson’s Disease
The neurodegenerative disorder known as Parkinson’s disease (PD) affects many people. The objective of this investig...
Parkinson’s Disease and MicroRNAs: A Duel Between Inhibition and Stimulation of Apoptosis in Neuronal Cells
Parkinson’s Disease and MicroRNAs: A Duel Between Inhibition and Stimulation of Apoptosis in Neuronal Cells
Parkinson’s disease (PD) is one of the most prevalent diseases of central nervous system that is caused by degenerat...
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation
NUS1 encodes the Nogo-B receptor, a critical regulator for unfolded protein reaction (UPR) signaling. Although several los...
Identification of Anoikis-Related Genes in Spinal Cord Injury: Bioinformatics and Experimental Validation
Identification of Anoikis-Related Genes in Spinal Cord Injury: Bioinformatics and Experimental Validation
Spinal cord injury (SCI) is a serious disease without effective therapeutic strategies. To identify the potential treatmen...
Causal Relationships Between Gut Microbiota, Inflammatory Cells/Proteins, and Subarachnoid Hemorrhage: A Multi-omics Bidirectional Mendelian Randomization Study and Meta-analysis
Causal Relationships Between Gut Microbiota, Inflammatory Cells/Proteins, and Subarachnoid Hemorrhage: A Multi-omics Bidirectional Mendelian Randomization Study and Meta-analysis
Subarachnoid hemorrhage (SAH) is a neurological emergency that can lead to fatal outcomes. It occurs when bleeding happens...
Levomilnacipran Improves Lipopolysaccharide-Induced Dysregulation of Synaptic Plasticity and Depression-Like Behaviors via Activating BDNF/TrkB Mediated PI3K/Akt/mTOR Signaling Pathway
Levomilnacipran Improves Lipopolysaccharide-Induced Dysregulation of Synaptic Plasticity and Depression-Like Behaviors via Activating BDNF/TrkB Mediated PI3K/Akt/mTOR Signaling Pathway
Depression is a common psychological disease with high morbidity and mortality. Recently, the involvement of synaptic plas...
Laminar Distribution of Cannabinoid Receptor 1 in the Prefrontal Cortex of Nonhuman Primates
Laminar Distribution of Cannabinoid Receptor 1 in the Prefrontal Cortex of Nonhuman Primates
Cannabis is an annual herb of the genus Cannabis, with a history of medical use going back thousands of years. However, it...
Understanding Glycogen Synthase Kinase-3: A Novel Avenue for Alzheimer’s Disease
Understanding Glycogen Synthase Kinase-3: A Novel Avenue for Alzheimer’s Disease
Alzheimer’s Disease (AD) is the most prevalent form of age-related dementia. Even though a century has passed since ...
Association of Biochemical Parameters and Screening for Mutations in the MCU Gene in Alzheimer’s Disease Patients
Association of Biochemical Parameters and Screening for Mutations in the MCU Gene in Alzheimer’s Disease Patients
The most prevalent form of dementia, Alzheimer’s disease (AD) is a chronic illness that is on the rise among the ger...
Oligodeoxynucleotide IMT504: Effects on Central Nervous System Repair Following Demyelination
Oligodeoxynucleotide IMT504: Effects on Central Nervous System Repair Following Demyelination
Multiple sclerosis (MS) is an immune-mediated central nervous system (CNS) disease characterized by demyelination resultin...
Nano-Mediated Molecular Targeting in Diagnosis and Mitigation of Wilson Disease
Nano-Mediated Molecular Targeting in Diagnosis and Mitigation of Wilson Disease
Wilson disease, a rare genetic disorder resulting from mutations in the ATP7B gene disrupts copper metabolism, leading to ...
Posttreatment with PaPE-1 Protects from Aβ-Induced Neurodegeneration Through Inhibiting the Expression of Alzheimer’s Disease-Related Genes and Apoptosis Process That Involves Enhanced DNA Methylation of Specific Genes
Posttreatment with PaPE-1 Protects from Aβ-Induced Neurodegeneration Through Inhibiting the Expression of Alzheimer’s Disease-Related Genes and Apoptosis Process That Involves Enhanced DNA Methylation of Specific Genes
Targeting the non-nuclear estrogen receptor (ER) signaling has been postulated as novel therapeutic strategy for central n...
Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy
Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy
Spinal cord injury (SCI) is a serious disabling central nervous system injury that can lead to motor, sensory, and autonom...
Inhibiting Caveolin-1-Related Akt/mTOR Signaling Pathway Protects Against N-methyl-D-Aspartate Receptor Activation-Mediated Dysfunction of Blood–Brain Barrier in vitro
Inhibiting Caveolin-1-Related Akt/mTOR Signaling Pathway Protects Against N-methyl-D-Aspartate Receptor Activation-Mediated Dysfunction of Blood–Brain Barrier in vitro
The aim of this study was to further explore the role of caveolin-1 (Cav-1) related Akt/mTOR signaling pathway in blood br...
Effects of Intestinal M Cells on Intestinal Barrier and Neuropathological Properties in an AD Mouse Model
Effects of Intestinal M Cells on Intestinal Barrier and Neuropathological Properties in an AD Mouse Model
Intestinal microfold cells (M cells) play a critical role in the immune response of the intestinal mucosa by actively taki...
Deferoxamine Ameliorates Cypermethrin-Induced Iron Accumulation and Associated Alterations
Deferoxamine Ameliorates Cypermethrin-Induced Iron Accumulation and Associated Alterations
Iron is widely linked with the onset and development of Parkinson’s disease (PD). Accumulation of iron induces free ...
Integrative Metabolomics and Whole Transcriptome Sequencing Reveal Role for TREM2 in Metabolism Homeostasis in Alzheimer’s Disease
Integrative Metabolomics and Whole Transcriptome Sequencing Reveal Role for TREM2 in Metabolism Homeostasis in Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia worldwide...
CircTrim37 Ameliorates Intracerebral Hemorrhage Outcomes by Modulating Microglial Polarization via the miR-30c-5p/SOCS3 Axis
CircTrim37 Ameliorates Intracerebral Hemorrhage Outcomes by Modulating Microglial Polarization via the miR-30c-5p/SOCS3 Axis
Circular RNAs (circRNAs) have been progressively recognized as critical regulators in the pathology and pathophysiology of...
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