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hsa-miR-3529-5p through F2RL3 Regulation as an Enhancer of Sensitivity to Cisplatin
hsa-miR-3529-5p through F2RL3 Regulation as an Enhancer of Sensitivity to Cisplatin
The emergence of drug resistance in gastric cancer presents a critical challenge in oncological treatments, often leading ...
Effect of Unmetabolized Folic Acid on Immunoinflammatory Markers in Sickle Cell Disease Patients Taking Folic Acid Supplementation
Effect of Unmetabolized Folic Acid on Immunoinflammatory Markers in Sickle Cell Disease Patients Taking Folic Acid Supplementation
Folic acid (FA) supplementation in sickle cell disease (SCD) patients lead to accumulation of unmetabolized folic acid (UM...
Optimization of Automated Dimethylmethylene Blue Assay for Quantification of Pediatric Urine Samples
Optimization of Automated Dimethylmethylene Blue Assay for Quantification of Pediatric Urine Samples
The metachromatic dye dimethylmethylene blue is used to quantify total glycosaminoglycans in urine. Understanding the inte...
Anti-tumor Effects of Polyphenols via Targeting Cancer Driving Signaling Pathways: A Review
Anti-tumor Effects of Polyphenols via Targeting Cancer Driving Signaling Pathways: A Review
The use of drugs in chemotherapy poses numerous side effects. Hence the use of natural substances that can help in the pre...
Circulating miRNA-373 and Vascular Endothelial Growth Factor as Potential Biomarkers for Early Detection of Breast Cancer
Circulating miRNA-373 and Vascular Endothelial Growth Factor as Potential Biomarkers for Early Detection of Breast Cancer
Breast cancer is the leading cause of cancer-related mortality among women worldwide. MicroRNAs (miRNAs), short non-coding...
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
Medulloblastoma (MB), a malignant tumour arising in the brain, exhibits distinct microRNA expression patterns. One such mi...
Assessment of Oxidative Stress Levels in Women with Different Phenotypes of Polycystic Ovary Syndrome and its Correlation with Lipid and Hormonal Profile
Assessment of Oxidative Stress Levels in Women with Different Phenotypes of Polycystic Ovary Syndrome and its Correlation with Lipid and Hormonal Profile
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder and one of the leading causes of infertility in women....
Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy
Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy
Colon rectal cancer still stands as the third most common form of cancer worldwide. 90% of colorectal cancer failure is at...
Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) is associated with low-grade systemic inflammation and an increase in inflammation mark...
The Increase of Soluble Urokinase Plasminogen Activator Receptor in Heart Failure is Related to Disease Severity and Cardiac Mortality
The Increase of Soluble Urokinase Plasminogen Activator Receptor in Heart Failure is Related to Disease Severity and Cardiac Mortality
Heart failure (HF) is a life-threatening syndrome with high prevalence and mortality rates. Soluble urokinase plasminogen ...
Role of Cell-free DNA as a Non-Invasive Biomarker in the Detection of Head and Neck Squamous Cell Carcinoma
Role of Cell-free DNA as a Non-Invasive Biomarker in the Detection of Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinomas (HNSCC) are the sixth leading cancer by incidence worldwide. Small fragments of cel...
Metabolomic Biomarkers for Prognosis in Non-Muscle Invasive Bladder Cancer: A Comprehensive Systematic Review and Meta-Analysis
Metabolomic Biomarkers for Prognosis in Non-Muscle Invasive Bladder Cancer: A Comprehensive Systematic Review and Meta-Analysis
The prognostic biomarkers, or metabolites, have gained relevance due to their significance in predicting clinical and ther...
Role of Blood Cell Indexes in Progresses to ESRD
Role of Blood Cell Indexes in Progresses to ESRD
Chronic kidney disease (CKD) is a complex health condition characterized by the gradual loss of renal function, often lead...
Spirulina Platensis Alleviates γ- Radiation-Induced Brain Damage by Attenuating Oxidative Stress and Increasing Brain-Derived Neurotrophic Factor (BDNF) Levels in Male Albino Rats
Spirulina Platensis Alleviates γ- Radiation-Induced Brain Damage by Attenuating Oxidative Stress and Increasing Brain-Derived Neurotrophic Factor (BDNF) Levels in Male Albino Rats
Ionizing radiation can irreversibly damage the brain cells’ function and structure. Spirulina platensis (Sp...
The First-Ever Investigation of SNP rs119461977 in SECISBP2/SBP2 Gene and its Implications for Hypothyroidism: A Novel Case–Control Research
The First-Ever Investigation of SNP rs119461977 in SECISBP2/SBP2 Gene and its Implications for Hypothyroidism: A Novel Case–Control Research
Hypothyroidism is one of the most prevalent endocrine disorders worldwide. Various genes are involved in thyroid hormone p...
Exploring the Role of Serum Lysyl Oxidase (LOX) Levels and LOX Gene Polymorphism (G473A) in Diabetic Nephropathy
Exploring the Role of Serum Lysyl Oxidase (LOX) Levels and LOX Gene Polymorphism (G473A) in Diabetic Nephropathy
Diabetic Nephropathy (DN) is a leading microvascular complication of diabetes with poor prognosis. Extra cellular matrix a...
Genetic Variants of AGO1*rs595961 and AGO2*rs4961280 with Susceptibility to Bladder Carcinoma
Genetic Variants of AGO1*rs595961 and AGO2*rs4961280 with Susceptibility to Bladder Carcinoma
The microRNA (miRNA) biogenesis mechanism remains elusive, yet various genetic variants may play a role in predicting the ...
Evaluation of Proflo-U® Platform: A Novel Fluorescence-Based Point of Care Device for Quantitative Estimation of Urine Albumin
Evaluation of Proflo-U® Platform: A Novel Fluorescence-Based Point of Care Device for Quantitative Estimation of Urine Albumin
Urine albumin estimation has a very high diagnostic significance. The scope of this assay widens if the method has potenti...
Predictive Value of Lymphocyte Based Indices to Determine Major Adverse Cardiovascular Events in Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Predictive Value of Lymphocyte Based Indices to Determine Major Adverse Cardiovascular Events in Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Acute coronary syndrome (ACS) is leading cause of mortality worldwide. Percutaneous coronary intervention (PCI) is the mai...
Exploring the Diagnostic Utility of Serum Cofilin-1 and 2 Levels in Patients with Acute Coronary Syndrome: A Case–Control Pilot Study
Exploring the Diagnostic Utility of Serum Cofilin-1 and 2 Levels in Patients with Acute Coronary Syndrome: A Case–Control Pilot Study
Acute coronary syndrome (ACS) is caused by decreased blood flow to the heart muscle after plaque rupture and thrombus form...
Lack of Glutamate Synthase in Streptococcus zooepidemicus makes a Natural Driving Force for Increasing Hyaluronic Acid Production
Lack of Glutamate Synthase in Streptococcus zooepidemicus makes a Natural Driving Force for Increasing Hyaluronic Acid Production
Hyaluronic acid (HA) has many applications in the pharmaceutical and cosmetic industries. Streptococcus zooepidemicus is n...
Assessing Colorectal Cancer Susceptibility in Kashmir, India: Insights from Xenobiotic Metabolism Gene Variants and Family Cancer History—A Comprehensive Case–Control Study
Assessing Colorectal Cancer Susceptibility in Kashmir, India: Insights from Xenobiotic Metabolism Gene Variants and Family Cancer History—A Comprehensive Case–Control Study
A family history of cancer(FHC) is a known risk factor for CRC with both genetic and other factors. A case–control s...
Point-of-Care Capillary Compared to Venous Bilirubin Measurement in Neonates
Point-of-Care Capillary Compared to Venous Bilirubin Measurement in Neonates
We aimed to evaluate the agreement between the point-of-care (POC) capillary bilirubin measurement with POC venous samples...
Exploring the Interplay Between Micronutrients and Cytokine Storm in Children with Multisystem Inflammatory Syndrome: ‘A Potential Mechanical Insight’
Exploring the Interplay Between Micronutrients and Cytokine Storm in Children with Multisystem Inflammatory Syndrome: ‘A Potential Mechanical Insight’
Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition linked to SARS-CoV-2 infection. MIS-...
Utility of Urinary Biomarkers for Diagnosis of Acute Kidney Injury (AKI) in COVID-19
Utility of Urinary Biomarkers for Diagnosis of Acute Kidney Injury (AKI) in COVID-19
Acute kidney injury (AKI) is a complication of COVID-19 and urinary biomarkers of renal “stress” and “in...
Cancer Vaccines: A Novel Revolutionized Approach to Cancer Therapy
Cancer Vaccines: A Novel Revolutionized Approach to Cancer Therapy
Over the past few decades, there has been significant advancement in the field of tumor immunotherapy. For many years vacc...
Co-existence of Congenital Hypothyroidism (CH) and TBG-Excess in a Boy Causing Simultaneous Elevation in Thyroid Stimulating Hormone (TSH) and Thyroxine (T4) Levels: First Report from India and Review of the Literature
Co-existence of Congenital Hypothyroidism (CH) and TBG-Excess in a Boy Causing Simultaneous Elevation in Thyroid Stimulating Hormone (TSH) and Thyroxine (T4) Levels: First Report from India and Review of the Literature
A certain population of patients exhibits discordant thyroid function tests (TFT) consistently along with unclear symptoms...
SHR0302 Improves Treg/Th17 Imbalance in Patients with Systemic Lupus Erythematosus
SHR0302 Improves Treg/Th17 Imbalance in Patients with Systemic Lupus Erythematosus
IL-6-mediated JAK1/STAT3 signaling pathway is involved in the development of Th17 cells, which play an essential role in t...
Differential Impact of VNTR Polymorphism in the CBS Gene on Gastric and Breast Cancers Risk
Differential Impact of VNTR Polymorphism in the CBS Gene on Gastric and Breast Cancers Risk
The cystathionine beta-synthase (CBS) gene plays a critical role in numerous physiological processes, including cellular p...
Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties
Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties
Sweet bell pepper (SBP, Capsicum annuum L.) can be employed as a spice in many dishes and may also be eaten as a delicious...
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