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CIMB, Vol. 45, Pages 212-222: Identification of Specific Pathogen-Infected sRNA-Mediated Interactions between Turnip Yellows Virus and Arabidopsis thaliana
Virus infestation can seriously harm the host plant’s growth and development. Turnip yellows virus (TuYV) infest...
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CIMB, Vol. 45, Pages 12-32: The Potential of Stilbene Compounds to Inhibit Mpro Protease as a Natural Treatment Strategy for Coronavirus Disease-2019
COVID-19 disease has had a global impact on human health with increased levels of morbidity and mortality. There is an unm...
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CIMB, Vol. 45, Pages 197-211: Molecular Mechanism of Gibberellins in Mesocotyl Elongation Response to Deep-Sowing Stress in Sweet Maize
Uneven germination is still a common problem in sweet maize planting. The mesocotyl is a key driver for ground-breaking sw...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 175-196: In Vitro Anticancer Properties of Novel Bis-Triazoles
Here, we describe the anticancer activity of our novel bis-triazoles MS47 and MS49, developed previously as G-quadruplex s...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 151-163: LSD1 for the Targeted Regulation of Adipose Tissue
White and thermal (brown and beige) adipose tissue energy storage and oxidative regulation pathways play a central role in...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 164-174: Flow Cytometry Detection of Anthracycline-Treated Breast Cancer Cells: An Optimized Protocol
The use of anthracycline derivatives was approved for the treatment of a broad spectrum of human tumors (i.e., breast canc...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 1-11: Regulation of Pro-Inflammatory Macrophage Polarization via Lipid Nanoparticles Mediated Delivery of Anti-Prostaglandin-E2 siRNA
Pro-inflammatory macrophage polarization is crucial in acute inflammatory diseases like Acute lung injury (ALI), and acute...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 141-150: EST-SSR Markers’ Development Based on RNA-Sequencing and Their Application in Population Genetic Structure and Diversity Analysis of Eleusine indica in China
Goosegrass (Eleusine indica) is one of the worst agricultural weeds in China. Molecular markers were developed for genetic...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 134-140: Association of Netrin 1 with hsCRP in Subjects with Obesity and Recent Diagnosis of Type 2 Diabetes
Netrin 1 (Ntn1) is a cell migration protein with an anti-inflammatory effect, which may play a key role in the pathologica...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 122-133: Genome-Wide Identification and Characterization of the AlkB Gene Family in Sweet Orange (Citrus sinensis)
Sweet orange (Citrus sinensis) is a sub-tropical fruit crop with important economic value that is popular worldwide; howev...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 110-121: The Function of BDNF and Its Receptor in the Male Genitourinary System and Its Potential Clinical Application
Background: Brain-derived neurotrophic factor (BDNF), as a member of the nerve growth factor family, has been mentioned mo...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 92-109: Design, Synthesis, Characterization, and Analysis of Antimicrobial Property of Novel Benzophenone Fused Azetidinone Derivatives through In Vitro and In Silico Approach
A sequence of novel 2-(4-benzoyl-2-methyl-phenoxy)-N-(3-chloro-2-oxo-4-phenyl-azetidin-1-yl)-acetamide analogues 9(a&n...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 78-91: Liver Damage and microRNAs: An Update
One of the major organs in the body with multiple functions is the liver. It plays a central role in the transformation of...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6385-6396: Genome-Wide Identification of Brassica napus PEN1-LIKE Genes and Their Expression Profiling in Insect-Susceptible and Resistant Cultivars
Recently, it has been reported that a gene (PEN1) in Arabidopsis thaliana is highly resistant to Plutella xylostella. We s...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6404-6427: Comprehensive Analysis of Glutamate Receptor-like Genes in Rice (Oryza sativa L.): Genome-Wide Identification, Characteristics, Evolution, Chromatin Accessibility, gcHap Diversity, Population Variation and Expression Analysis
Glutamate receptors (GLR) are widely present in animals and plants, playing essential roles in regulating plant growth, de...
Current Issues In Molecular Biology
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CIMB, Vol. 45, Pages 33-50: Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19
SARS-CoV-2 causes the complex and heterogeneous illness known as COVID-19. The disease primarily affects the respiratory s...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6323-6332: Non-Peptide Agonists and Antagonists of the Prokineticin Receptors
The prokineticin family comprises a group of secreted peptides that can be classified as chemokines based on their structu...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6368-6384: Identification of Candidate Genes Associated with Pulp Color by Transcriptomic Analysis of ‘Huaxiu’ Plum (Prunus salicina Lindl.) during Fruit-Ripening
The plum (Prunus salicina Lindl.) is one of the traditional and economically important stone fruit trees in China. Anthocy...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6439-6449: Glutathione and Its Metabolic Enzymes in Gliomal Tumor Tissue and the Peritumoral Zone at Different Degrees of Anaplasia
This research was aimed at investigating the features of free radical activity and the parameters of glutathione metabolis...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6428-6438: Antileukemic Activity of hsa-miR-203a-5p by Limiting Glutathione Metabolism in Imatinib-Resistant K562 Cells
Imatinib has been the first and most successful tyrosine kinase inhibitor (TKI) for chronic myeloid leukemia (CML), but ma...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6397-6403: The First Homozygote Mutation c.499G>T (Asp167Tyr) in the RPE65 Gene Encoding Retinoid Isomerohydrolase Causing Retinal Dystrophy
RPE65, an abundant membrane-associated protein present in the retinal pigment epithelium (RPE), is a vital retinoid isomer...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6346-6367: Application and Molecular Mechanisms of Extracellular Vesicles Derived from Mesenchymal Stem Cells in Osteoporosis
Osteoporosis (OP) is a chronic bone disease characterized by decreased bone mass, destroyed bone microstructure, and incre...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6333-6345: TRPA1 Polymorphisms Modify the Hypotensive Responses to Propofol with No Change in Nitrite or Nitrate Levels
Anesthesia with propofol is frequently associated with hypotension. The TRPA1 gene contributes to the vasodilator effect o...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6306-6322: The Use of Salivary Levels of Matrix Metalloproteinases as an Adjuvant Method in the Early Diagnosis of Oral Squamous Cell Carcinoma: A Narrative Literature Review
Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with increased mortality, in which the early diagnosis is ...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6290-6305: Development of Post-Stroke Cognitive and Depressive Disturbances: Associations with Neurohumoral Indices
Neuropsychiatric complications, in particular cognitive and depressive disorders, are common consequences of ischemic stro...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6218-6228: Therapeutic Potential of 6-Gingerol in Prevention of Colon Cancer Induced by Azoxymethane through the Modulation of Antioxidant Potential and Inflammation
A polyphenolic component of ginger, 6-gingerol, is widely reported to possess antioxidant, anti-inflammatory and anticance...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6280-6289: An Exploratory In Vivo Study on the Effect of Annurca Apple Extract on Hair Growth in Mice
Hair loss is an important problem affecting the quality of life in modern society. Recent studies show that Annurca apple ...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6075-6092: Exploring and Identifying Candidate Genes and Genomic Regions Related to Economically Important Traits in Hanwoo Cattle
The purpose of the current review was to explore and summarize different studies concerning the detection and characteriza...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6132-6144: The Role of MRE11 in the IL-6/STAT3 Pathway of Lung Cancer Cells
MRE11 is a pivotal protein for ATM activation during double-strand DNA break. ATM kinase activations may act as lung cance...
Current Issues In Molecular Biology
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CIMB, Vol. 44, Pages 6257-6279: Microalgal Carotenoids: Therapeutic Application and Latest Approaches to Enhance the Production
Microalgae are microscopic photosynthetic organisms frequently found in fresh and marine water ecosystems. Various microal...
Current Issues In Molecular Biology
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