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Intermittent theta burst stimulation is superior to 10 Hz-repetitive transcranial magnetic stimulation in promoting episodic-like memory in healthy male rats by enhancing low γ oscillation and glutamate neuronal activities of the anterior cingulate cortex
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation technique commonly used in clinical...
Activation or blockade of prelimbic 5-HT4 receptors improves working memory in hemiparkinsonian rats
Parkinson's disease (PD) is a progressive degenerative condition of the central nervous system, pathologically characteriz...
Bioactive ROS-responsive nanotherapeutics attenuate intermittent hypoxia-induced cognitive impairment via NRF2/KEAP1/HO-1 signaling
Obstructive sleep apnea (OSA), a prevalent disorder marked by recurrent upper airway obstruction during sleep, results in ...
Gastrin-releasing peptide in the paraventricular nucleus exerts hypertensive effects in preeclampsia
BackgroundPreeclampsia (PE) is a pregnancy complication associated with hypertension, whose central mechanism remains uncl...
Epigenetic regulation of immune cells in central nervous system: from steady state to pathology
Epigenetic regulation has been demonstrated as an important approach that controls gene activity without altering the DNA ...
DNA methylation and hydroxymethylation dynamics in the aging brain and its impact on ischemic stroke
Epigenetic signatures in the mammalian genome, including DNA and histone modifications, control tissue- and context-specif...
Neurochemical in vivo microdialysis and postmortem tissue analysis of amygdala endocannabinoid levels after MAGL- and FAAH-inhibition in rodents
The endocannabinoid system functions as a significant neuromodulatory network, playing a central role in molecular process...
Epitranscriptomic shifts in M6A RNA methylation influencing transcriptional dynamics in the prefrontal cortex of chronic restraint stress rats
Chronic restraint stress (CRS) is a widely used model for investigating stress-induced molecular and neuronal changes. In ...
Pathway-specific regulation of amphetamine-induced conditioned place preference by chemogenetic modulation of basolateral amygdala projections to prelimbic cortex and nucleus accumbens subregions
Individuals with substance use disorders (SUDs) display maladaptive associative learning, in which contextual cues linked ...
Differential synaptic inhibition and serotonin 5-HT7 receptor-mediated modulation in identified dorsal horn neurons
Serotonergic modulation of pain transmission in the spinal cord involves the activation of multiple receptor types, includ...
Antinociceptive and anti-inflammatory effects of dihydroaustrasulfone alcohol in alleviating peripheral neuropathy via Nrf2/HO-1 pathway in rats
Neuropathic pain, which affects 7–10 % of the global population and decreases productivity and performance at work (Kawai ...
Deferoxamine prevents BBB disruption, neuroinflammation and apoptotic changes in early hours of ischemic reperfusion injury
Ischemic stroke (IS) is contemplated as a condition that causes a decrease in oxygen and nutrients reaching the brain due ...
Anti-inflammatory and analgesic effects of marine-derived antimicrobial peptide tilapia piscidin 3(TP3) in alleviating chronic constriction injury-induced neuropathic pain in rats
Neuropathic pain, a debilitating condition affecting millions worldwide, results from lesions or diseases that impair the ...
Thiamet-G ameliorates Parkinson's disease-associated cognitive impairment via increasing O-GlcNAcylation of STING in the microglia
Parkinson's disease (PD), recognized as the second most common neurodegenerative disorder following Alzheimer's disease, h...
N-acetyltransferase 10 in the nucleus accumbens participates in methamphetamine-induced conditioned place preference and hyperlocomotion in mice
Drug dependence remains one of the most persistent threats to public health, causing serious negative consequences for ind...
Acute ketamine enhances social behavior and dendritic plasticity in the amygdala by increasing BDNF, GAP43, and TRKB presence following excitotoxic neonatal ibotenic acid lesion
Schizophrenia is a highly disabling psychopathology that places a significant burden on public health systems (Solmi et al...
The potentiating activity of benzodiazepine site of the GABA(A) receptor is inhibited by competitive antagonists of orthosteric site
γ-aminobutyric acid (GABA) is the main inhibitory transmitter of the brain, and the GABAA receptor is the main element of ...
Refinement of TSLP expression mediates chronic allodynia associated with IL22/STAT3 axis
Chronic allodynia, characterized by aversive nociceptive and emotional alterations, is featured with a painful response to...
Combined administration of cocaine and alcohol alters the expression of brain peptide/protein profiles in rats: a MALDI imaging mass spectrometry approach
While the concurrent use of alcohol and cocaine is common in patterns of polysubstance use, little is known about the comb...
Repetitive transcranial magnetic stimulation as a universal modulator of synaptic plasticity: Bridging the gap between functional and structural plasticity
Transcranial magnetic stimulation (TMS) is a painless, non-invasive neuromodulatory technique used in diagnostics, therapy...
Ras, RhoA, and vascular pharmacology in neurodevelopment and aging
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Reassessment of capsaicin desensitization in the rodent spinal dorsal horn
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Neuron-selective and activity-dependent splicing of BDNF exon I–IX pre-mRNA
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Discriminating fingerprints of chronic neuropathic pain following spinal cord injury using artificial neural networks and mass spectrometry analysis of female mice serum
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Altered sex differences related to food intake, hedonic preference, and FosB/deltaFosB expression within central neural circuit involved in homeostatic and hedonic food intake regulation in Shank3B mouse model of autism spectrum disorder
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Neuroprotective and anti-inflammatory effects of the RIPK3 inhibitor GSK872 in an MPTP-induced mouse model of Parkinson's disease
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Impairment of neuromotor development and cognition associated with histopathological and neurochemical abnormalities in the cerebral cortex and striatum of glutaryl-CoA dehydrogenase deficient mice
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The wnt/pyruvate kinase, muscle axis plays an essential role in the differentiation of mouse neuroblastoma cells
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Boron: An intriguing factor in retarding Alzheimer's progression
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An overview of the relationship between inflammation and cognitive function in humans, molecular pathways and the impact of nutraceuticals
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