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The GPCR adaptor protein Norbin controls the trafficking of C5aR1 and CXCR4 in mouse neutrophils
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The NEDD4-binding protein N4BP1 degrades mRNA substrates through the coding sequence independent of nonsense-mediated decay
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Duality in disease: How two amino acid substitutions at actin residue 312 result in opposing forms of cardiomyopathy
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Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration
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RNA G-quadruplexes and calcium ions synergistically induce Tau phase transition in vitro
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Structural profiles of the full phagocyte NADPH oxidase unveiled by combining computational biology and experimental knowledge
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Mechanisms of amphibian arrestin 1 self-association and dynamic distribution in retinal photoreceptors
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Bidirectional transfer of a small membrane-impermeable molecule between the Caenorhabditis elegans intestine and germline
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Structure–function analysis of tRNA t6A-catalysis, assembly, and thermostability of Aquifex aeolicus TsaD2B2 tetramer in complex with TsaE
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Characterization of atypical BAR domain-containing proteins coded by Toxoplasma gondii
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Complex sporulation-specific expression of transcription termination factor Rho highlights its involvement in Bacillus subtilis cell differentiation
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Distinct chemical structures inhibit the CEMIP hyaluronidase and promote oligodendrocyte progenitor cell maturation
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TFEB agonist clomiphene citrate activates the autophagy-lysosomal pathway and ameliorates Alzheimer's disease symptoms in mice
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Phosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange
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Epididymis-specific RNase A family genes regulate fertility and small RNA processing
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PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation
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Correction: Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core
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The signaling landscape of insulin-like growth factor 1
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Structural Basis for the Pathogenicity of Parkin Catalytic Domain Mutants
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Histone Variants: The Bricks That Fit Differently
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The molecular principles underlying diverse functions of the SLC26 family of proteins
The molecular principles underlying diverse functions of the SLC26 family of proteins
Author links open overlay panel, AbstractMammalian SLC26 proteins are membrane-based anion transporters that belong to the...
The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim (PAS) domains
The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim (PAS) domains
Timothy H. S. Cho: Conceptualization, Investigation, Visualization, Methodology, Writing – Original Draft Cameron Murray: ...
Biochemical characterization of E. coli DnaC variants that alter DnaB helicase loading onto DNA
Biochemical characterization of E. coli DnaC variants that alter DnaB helicase loading onto DNA
Author links open overlay panel, AbstractDNA replication in E. coli starts with loading of the replicative helicase, DnaB,...
Immunometabolic crosstalk in Aedes fluviatilis Wolbachia pipientis symbiosis
Immunometabolic crosstalk in Aedes fluviatilis Wolbachia pipientis symbiosis
Author links open overlay panel, , , , , , , , , , ABSTRACTWolbachia pipientis is a maternally transmitted symbiotic bacte...
Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N1-aminopropylagmatine synthases
Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N1-aminopropylagmatine synthases
Spermine synthase is an aminopropyltransferase that adds an aminopropyl group to the essential polyamine spermidine to for...
The luciferase-based in vivo protein-protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction.
The luciferase-based in vivo protein-protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction.
Author links open overlay panel, , , , , , , , , , , AbstractProtein phosphatase 2A (PP2A) is an essential serine/threonin...
Phospholamban inhibits the cardiac calcium pump by interrupting an allosteric activation pathway
Phospholamban inhibits the cardiac calcium pump by interrupting an allosteric activation pathway
allosteric regulationbiosensorcalcium ATPasecalcium transportcardiac musclefluorescence resonance energy transfer (FRET)mo...
Coenzyme Q4 is a functional substitute for coenzyme Q10 and can be targeted to the mitochondria
Coenzyme Q4 is a functional substitute for coenzyme Q10 and can be targeted to the mitochondria
KEYWORDSCoenzyme Q10 (CoQ10)UbiquinoneMitochondrial respiratory chain complexMitochondrial therapeuticsMembrane lipidBioen...
Pathogenic residue insertion in a neuronal nicotinic receptor alters intra- and inter-subunit interactions that tune channel gating
Pathogenic residue insertion in a neuronal nicotinic receptor alters intra- and inter-subunit interactions that tune channel gating
Research Article Collection: Molecular Bases of DiseasePathogenic residue insertion in a neuronal nicotinic receptor alter...
ARV1 deficiency induces lipid bilayer stress and enhances rDNA stability by activating the unfolded protein response in Saccharomyces cerevisiae
ARV1 deficiency induces lipid bilayer stress and enhances rDNA stability by activating the unfolded protein response in Saccharomyces cerevisiae
The stability of ribosomal DNA (rDNA) is maintained through transcriptional silencing by the NAD+-dependent histone deacet...
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