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Thermodynamic and Electrochemical Characteristics of Urine Protein Molecules That Affect the Formation of Stones
Thermodynamic and Electrochemical Characteristics of Urine Protein Molecules That Affect the Formation of Stones
Pathogenetic development of urolithiasis (UL) can be divided chronologically into prestone phase and stone phase. Specific...
Prospects for the Application of Synthetic Zeolites as Components of Wound Coverings and Selective Hemosorbents
Prospects for the Application of Synthetic Zeolites as Components of Wound Coverings and Selective Hemosorbents
The issues of potential applicability of synthetic framework aluminosilicates (zeolites) as components of medical material...
Cj0983 and Cj0090 Lipoproteins Contain Potential Linear Peptide Epitopes for Anti- Vaccine Applications
Cj0983 and Cj0090 Lipoproteins Contain Potential Linear Peptide Epitopes for Anti- Vaccine Applications
Campylobacter jejuni, a Gram-negative bacterium, is the major etiologic agent of campylobacteriosis responsible for approx...
Study of Metabolic Plasticity of the Brain in Animals with Modeled Parkinson’s Disease
Study of Metabolic Plasticity of the Brain in Animals with Modeled Parkinson’s Disease
Neuroinflammation plays the key role in progression of Parkinson’s disease (PD), the neurodegenerative disorder char...
Detection of Replication-Competent Adenoviral Particles in the Vector Vaccines Salnavac® and Gam-Covid-Vac® against the New Coronavirus Infection Covid-19
Detection of Replication-Competent Adenoviral Particles in the Vector Vaccines Salnavac® and Gam-Covid-Vac® against the New Coronavirus Infection Covid-19
The 2019–2022 coronavirus pandemic has brought vaccination to the forefront in recent years. As a result, various ap...
Variability in the Content of 8-Hydroxy-2-deoxyguanosine as a Marker of Oxidative Stress during Subchronic Intoxication with Pesticides
Variability in the Content of 8-Hydroxy-2-deoxyguanosine as a Marker of Oxidative Stress during Subchronic Intoxication with Pesticides
In this study, a change in the concentration of 8-hydroxy-2-deoxyguanosine (8-OHdG) in the oral fluid and plasma of model ...
Isolation, Identification, and Cytotoxicity of α-Alectoronic and α-Collatolic Acids Isolated from the Lichen
Isolation, Identification, and Cytotoxicity of α-Alectoronic and α-Collatolic Acids Isolated from the Lichen
The results of the study on isolation, purification, and study of the cytotoxicity of α-alectoronic and α-collat...
Organotin Complexes—Candidates for Antitumor Agents: Toxicity vs. Pharmaceutical Activity
Organotin Complexes—Candidates for Antitumor Agents: Toxicity vs. Pharmaceutical Activity
Chemotherapy is one of the promising areas for the treatment of cancer. Platinum-based drugs are widely used in clinical p...
Development of a Technology for Producing Therapeutic Peptides Weighting Less Than 5 kDa in a Bacterial Expression System
Development of a Technology for Producing Therapeutic Peptides Weighting Less Than 5 kDa in a Bacterial Expression System
Therapeutic peptides are an interesting class of pharmaceutical compounds that are structurally intermediate between small...
Hepatitis C Specificity in Lowering Serum Lipids of Patients with Chronic Renal Failure
Hepatitis C Specificity in Lowering Serum Lipids of Patients with Chronic Renal Failure
This study describes the effects of the hepatitis C virus on lipid profile and some other parameters in patients with CRF....
Regenerative Medicine Technologies in Dentistry: Tissue Engineering in Dental Implantation
Regenerative Medicine Technologies in Dentistry: Tissue Engineering in Dental Implantation
In recent years, regenerative medicine technologies, especially tissue engineering, have been increasingly used in dental ...
Thrombopoiesis and Androgen Biosynthesis in Patients with Adrenal Cortex Tumors
Thrombopoiesis and Androgen Biosynthesis in Patients with Adrenal Cortex Tumors
The results of experimental and clinical studies indicate the involvement of platelets in the process of progression of ma...
Relationship between the Level of Alcohol Use and the Concentrations of Some Neuropeptides and Proteins in Blood Serum
Relationship between the Level of Alcohol Use and the Concentrations of Some Neuropeptides and Proteins in Blood Serum
The development of novel highly informative approaches to the assessment of chronic alcohol use is still an urgent problem...
Indole-3-carbinol and Different Classes of Polyphenols in the Regulation of the Activity of the Nrf2/Keap1/ARE Signaling System
Indole-3-carbinol and Different Classes of Polyphenols in the Regulation of the Activity of the Nrf2/Keap1/ARE Signaling System
Nutriome is a set of alimentary factors for maintaining the body’s adaptive potential. Of particular importance for ...
Rhizome Lectin Induces Apoptosis in Human Lung Cancer Cells and Inhibits the Growth of Ehrlich Ascites Carcinoma Cells in Mice
Rhizome Lectin Induces Apoptosis in Human Lung Cancer Cells and Inhibits the Growth of Ehrlich Ascites Carcinoma Cells in Mice
Geodoram densiflorum or pink nodding orchid grows in wet habitats in Bangladesh. Rural people traditionally use this orchi...
Potential Influence of Tryptophan Metabolites on Translocation of Bacterial DNA into the Blood in Normal Conditions and in Various Obesity Phenotypes
Potential Influence of Tryptophan Metabolites on Translocation of Bacterial DNA into the Blood in Normal Conditions and in Various Obesity Phenotypes
It is known that obesity changes the permeability of the intestinal wall, including for bacterial DNA. Therefore, obese pa...
Evaluation of Ornithine Decarboxylase and Ferric Reducing Capacity Levels as Potential Biomarkers for Polycystic Ovary Syndrome
Evaluation of Ornithine Decarboxylase and Ferric Reducing Capacity Levels as Potential Biomarkers for Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder affecting reproductive-age women, often link...
Construction of Expression Vectors for Efficient Production of Recombinant Proteins in E. coli for the Development of Therapeutic Drugs
Construction of Expression Vectors for Efficient Production of Recombinant Proteins in E. coli for the Development of Therapeutic Drugs
When developing vaccines and immunotherapeutic and enzymatic drugs, it is usually necessary to obtain a functional protein...
The Effects of Pretreatment with Atorvastatin, Fenofibrate, or Both Drugs in a Mouse Model of Acute Lipemia Induced by the General Lipase Inhibitor Poloxamer 407
The Effects of Pretreatment with Atorvastatin, Fenofibrate, or Both Drugs in a Mouse Model of Acute Lipemia Induced by the General Lipase Inhibitor Poloxamer 407
Dyslipidemia is a well-known risk factor for the development of cardiovascular diseases and atherosclerosis. The effects o...
The Role of Arachidonic Acid Metabolizing Cytochromes P450 in the Control of Cardiovascular Functions
The Role of Arachidonic Acid Metabolizing Cytochromes P450 in the Control of Cardiovascular Functions
Arachidonic acid (AA) is widely distributed in many organs and can be metabolized in several ways into small lipid molecul...
Effects of Various Poly(A) Tails on Luciferase Expression
Effects of Various Poly(A) Tails on Luciferase Expression
Synthesis of RNA by in vitro transcription has many applications in the production of vaccines, anticancer and gene therap...
Investigating Non-Covalent Interactions of Human Serum Albumin with Doxorubicin and Folic Acid
Investigating Non-Covalent Interactions of Human Serum Albumin with Doxorubicin and Folic Acid
The development of effective delivery systems for antitumor drugs with increased specificity and controlled release is one...
Expression of miR-21, miR-378a, miR-205, and Their Targets in ER-Positive Breast Tumors with Different HER2 Protein Levels
Expression of miR-21, miR-378a, miR-205, and Their Targets in ER-Positive Breast Tumors with Different HER2 Protein Levels
Tyrosine protein kinase HER2 plays an important role in carcinogenesis. In breast cancer (BC), the HER2 gene is amplified ...
The Influence of Increased Concentrations of Brain Natriuretic Peptide on the Level of Hemodynamic Reactions in Individuals Living and Working in the European North and the Arctic of the Russian Federation
The Influence of Increased Concentrations of Brain Natriuretic Peptide on the Level of Hemodynamic Reactions in Individuals Living and Working in the European North and the Arctic of the Russian Federation
The authors examined 111 practically healthy individuals (66 women and 45 men aged 46–55 years) living and working i...
Adaptation and Experimental Validation of Clinical RNA Sequencing Protocol Oncobox for MGI DNBSEQ-G50 Platform
Adaptation and Experimental Validation of Clinical RNA Sequencing Protocol Oncobox for MGI DNBSEQ-G50 Platform
RNA sequencing (RNAseq) is currently a method of choice for the high-throughput RNA-level analysis of gene expression. Fur...
A New Human Uveal Melanoma Cell Line: Melanin Production and Molecular Markers for Targeted Therapy
A New Human Uveal Melanoma Cell Line: Melanin Production and Molecular Markers for Targeted Therapy
A new human uveal melanoma (UM) cell line uMel1 was established by mechanical disintegration of a tumor fragment. uMel1 ce...
Levels of IgG to Food Antigens in Practically Healthy People and with Metabolic Syndrome
Levels of IgG to Food Antigens in Practically Healthy People and with Metabolic Syndrome
The study compared the content of IgG specific to 90 food antigens in practically healthy people and in people with metabo...
Glycation and Glucose Variability in Subjects with Type 1 Diabetes
Glycation and Glucose Variability in Subjects with Type 1 Diabetes
High glucose variability (GV) and increased glycation may play a role in the development of diabetes complications. We aim...
Investigating the Role of KLF6-SV1 as a Regulator of EMT Progression
Investigating the Role of KLF6-SV1 as a Regulator of EMT Progression
Post-translational modifications (PTMs) are crucial for all biological processes and offer insights into protein functions...
Investigation of the Several Aspects of Interaction between Human Serum Albumin and Oleic Acid by Molecular Dynamic Simulation Approaches and Spectroscopic Methods
Investigation of the Several Aspects of Interaction between Human Serum Albumin and Oleic Acid by Molecular Dynamic Simulation Approaches and Spectroscopic Methods
The most predominant fatty acid in olive oil, oleic acid (OA), lowers LDL (low-density lipoprotein) cholesterol and may ra...
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