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Cellular uptake of 2‐aminopyridine‐modified peptide nucleic acids conjugated with cell‐penetrating peptides
Cellular uptake of 2‐aminopyridine‐modified peptide nucleic acids conjugated with cell‐penetrating peptides
Abstract Cell-penetrating peptides (CPPs) have been extensively used to deliver peptide nucleic acid (PNA) in cells. We ha...
DNA‐assisted site‐selective protein modification
DNA‐assisted site‐selective protein modification
Abstract Protein modification is important for various types of biomedical research, including proteomics and therapeutics...
Cover Image
Cover Image
Endotoxin exists on the outer membrane of Gram-negative bacteria and poses risks to human health by triggering a series of...
Cyclopentane peptide nucleic acid: Gold nanoparticle conjugates for the detection of nucleic acids in a microfluidic format
Cyclopentane peptide nucleic acid: Gold nanoparticle conjugates for the detection of nucleic acids in a microfluidic format
Abstract Routine patient testing for viral infections is critical to identify infected individuals for treatment and to pr...
A comparison between β‐tricalcium phosphate verse chitosan poly‐caprolactone‐based 3D melt extruded composite scaffolds
A comparison between β‐tricalcium phosphate verse chitosan poly‐caprolactone‐based 3D melt extruded composite scaffolds
Abstract Melt extrusion 3D printing has become an attractive additive manufacturing technology to construct degradable sca...
Identifying N7‐methylguanosine sites by integrating multiple features
Identifying N7‐methylguanosine sites by integrating multiple features
Abstract Recent studies reported that N7-methylguanosine (m7G) plays a vital role in gene expression regulation. As a cons...
Fold‐switching proteins
Fold‐switching proteins
1 WHERE THE FIELD OF FOLD-SWITCHING PROTEINS STANDS TODAY This special issue of Biopolymers is dedicate...
Folding dynamics of polymorphic G‐quadruplex structures
Folding dynamics of polymorphic G‐quadruplex structures
Abstract G-quadruplexes (G4), found in numerous places within the human genome, are involved in essential processes of cel...
Rapid, multiplexed detection of the let‐7 miRNA family using γPNA amphiphiles in micelle‐tagging electrophoresis
Rapid, multiplexed detection of the let‐7 miRNA family using γPNA amphiphiles in micelle‐tagging electrophoresis
Abstract miRNA is a promising class of biomarkers whose levels can be assayed to detect various forms of cancer and other ...
Mechanisms and applications of peptide nucleic acids selectively binding to double‐stranded RNA
Mechanisms and applications of peptide nucleic acids selectively binding to double‐stranded RNA
Abstract RNAs form secondary structures containing double-stranded base paired regions and single-stranded regions. Probin...
Identification and characterization of metamorphic proteins: Current and future perspectives
Identification and characterization of metamorphic proteins: Current and future perspectives
Abstract Proteins that can reversibly alternate between distinctly different folds under native conditions are described a...
A simple fluorescent assay for the detection of peptide nucleic acid‐directed double strand duplex invasion
A simple fluorescent assay for the detection of peptide nucleic acid‐directed double strand duplex invasion
Abstract Peptide nucleic acid (PNA) is a mimic of nucleic acids that is able to bind complementary oligonucleotides with h...
A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions
A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions
Abstract Extant fold-switching proteins remodel their secondary structures and change their functions in response to cellu...
Spectroscopic, thermodynamic and kinetic analysis of selective triplex formation by peptide nucleic acid with double‐stranded RNA over its DNA counterpart
Spectroscopic, thermodynamic and kinetic analysis of selective triplex formation by peptide nucleic acid with double‐stranded RNA over its DNA counterpart
Abstract Unlike conventional triplex-forming oligonucleotide (TFO), triplex-forming peptide nucleic acid (PNA) can tightly...
Polydopamine nanofilms for high‐performance paper‐based electrochemical devices
Polydopamine nanofilms for high‐performance paper‐based electrochemical devices
Abstract Since the discovery of polydopamine (PDA), there has been a lot of progress on using this substance to functional...
Hierarchical assemblies of polypeptoids for rational design of advanced functional nanomaterials
Hierarchical assemblies of polypeptoids for rational design of advanced functional nanomaterials
Abstract Polypeptoids (poly-N-substituent glycines) are a class of highly tailorable peptidomimetic polymers. Polypeptoids...
Low endotoxin recovery and its impact on endotoxin detection
Low endotoxin recovery and its impact on endotoxin detection
Abstract Endotoxin exists on the outer membrane of Gram-negative bacteria and poses risks to human health by triggering a ...
Effect of amino acid composition of elastin‐like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis
Effect of amino acid composition of elastin‐like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis
Abstract Development of elastin-like polypeptide (ELP) biomaterials is widespread, but information critical for clinical d...
Corrigendum: Unnatural bases for recognition of noncoding nucleic acid interfaces
Corrigendum: Unnatural bases for recognition of noncoding nucleic acid interfaces
Article First Published: 24 September 2020 DOI: 10.1002/bip.23399 [Article in Biopol...
Toward conditional control of Smac mimetic activity by RNA‐templated reduction of azidopeptides on PNA or 2′‐OMe‐RNA
Toward conditional control of Smac mimetic activity by RNA‐templated reduction of azidopeptides on PNA or 2′‐OMe‐RNA
Abstract Oligonucleotide templated reactions can be used to control the activity of functional molecules based on the pres...
Electronic characteristics of BRCA1 mutations in DNA
Electronic characteristics of BRCA1 mutations in DNA
Abstract The efficient and low-cost way for gene mutation detection and identification are conducive for the detection of ...
Application of peptide nucleic acid in electrochemical nucleic acid biosensors
Application of peptide nucleic acid in electrochemical nucleic acid biosensors
Abstract The early diagnosis of major diseases, such as malignant tumors, has always been an important field of research. ...
Rapid self‐assembly of γPNA nanofibers at constant temperature
Rapid self‐assembly of γPNA nanofibers at constant temperature
Abstract Peptide nucleic acids (PNAs) have primarily been used to achieve therapeutic gene modulation through antisense st...
Corrigendum: PEGylated PAMAM dendrimers loading oxaliplatin with prolonged release and high payload without burst effect
Corrigendum: PEGylated PAMAM dendrimers loading oxaliplatin with prolonged release and high payload without burst effect
Corresponding Author Biomaterials and Nanotechnology Research Group, Faculty of...
Natural biopolymers as proton conductors in bioelectronics
Natural biopolymers as proton conductors in bioelectronics
Abstract Bioelectronic devices sense or deliver information at the interface between living systems and electronics by con...
Pyrrolidinyl peptide nucleic acids bearing hydroxy‐modified cyclobutane building blocks: Synthesis and binding properties
Pyrrolidinyl peptide nucleic acids bearing hydroxy‐modified cyclobutane building blocks: Synthesis and binding properties
Abstract The conformationally constrained pyrrolidinyl PNA with a dipeptide consisting of an alternating nucleobase-modifi...
Advances in chitooligosaccharides chemical modifications
Advances in chitooligosaccharides chemical modifications
Abstract Chitooligosaccharides (COS) differ from chitosan by their molar mass: those of COS are defined to be lower than 2...
Peptide nucleic acids and their role in gene regulation and editing
Peptide nucleic acids and their role in gene regulation and editing
Abstract The unique properties of peptide nucleic acid (PNA) makes it a desirable candidate to be used in therapeutic and ...
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