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Mechanisms and routes of G-protein coupled receptor-mediated Tau degradation in Alzheimer’s disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder (ND) mainly leading to memory loss, cognitive decline...
Cardiac and pericardial inflammatory changes and post-cardiac surgery atrial fibrillation
Dr. Mohammad El Diasty is a cardiac surgeon and Associate Professor of Surgery at the University Hospitals Cleveland Medic...
The role of innate lymphoid cells in kidney disease
The annual incidence of kidney disease is increasing and is becoming a major global public health issue that imposes a hea...
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A multidimensional immunological perspective on long COVID
Long COVID – also referred to as Post-Acute Sequelae of SARS-CoV-2 infection (PASC) or post-COVID-19 condition – is a comp...
Neuroprotective properties of ciliary neurotrophic factor in the retina for the treatment of macular telangiectasia type 2
Dr. Arne Nystuen has more than 20 years of research and development experience in both academic and industry settings. He ...
The central role of CXCL10-CXCR3 signaling in neuroinflammation and neuropathology
The central nervous system (CNS) has long been considered an immune-privileged compartment due to the presence of the bloo...
Innate immune activation and neuroinflammatory pathways in Epilepsy
Sushmita Jha is a Professor in the Department of Bioscience and Bioengineering at the Indian Institute of Technology Jodhp...
Role of growth factors and their interplay during oligodendroglial differentiation and maturation
Oligodendrocytes (OLs) produce myelin and provide metabolic support to axons via the myelin sheath. This sheath is a lipid...
Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy
Yu’e Liu, Ph.D. Dr. Yu’e Liu obtained her DBA degree from the Grenoble Ecole De Management (France) in 2019, and Ph.D. in ...
Necroptosis in sepsis: Mechanisms and therapeutic potential
Zhirong Qian holds a position at the Seventh Affiliated Hospital of Sun Yat-sen University and is a distinguished professo...
An emerging paradigm of CXCL16 involvement in cancer progression
George S. Karagiannis, D.V.M, Ph.D., is an assistant professor in the Department of Microbiology and Immunology at the Alb...
The secretion of interleukin-1β
Paula I. Seoane is a Postdoctoral Research Associate at Prof. David Brough’s lab at the University of Manchester, UK. Paul...
Leptin as a mechanistic link between obesity and systemic lupus erythematous
Dr. Víctor Sánchez-Margalet is Professor of Biochemistry and Molecular Biology at the University of Seville Medical School...
Exploring inflammatory and fibrotic mechanisms driving diabetic nephropathy progression
Diabetic nephropathy (DN) causes end-stage renal disease. Chelerythrine is renoprotective, but the pathway linking AMPK/mT...
Exploring AI tools and multi-omics for precision medicine in lung cancer therapy
Ms. Arpana Purohit is a research scholar of commendable merit at the Department of Pharmaceutical Sciences, Dr. Harisingh ...
Nuclear receptors in pulmonary hypertension: From pathophysiological mechanisms to clinical implications
Pulmonary hypertension (PH) is a disease syndrome that is typified by significant pulmonary vascular remodeling and a prog...
Neuro-endocrine-immune regulation of metabolic homeostasis
Xingzhong Feng, M.D., is a professor, chief physician, and doctoral supervisor, currently serving as Vice President of Yuq...
TLR-based therapeutic strategies for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) ranks as the fourth leading cause of cancer-related deaths globally [1]. The leading etiolo...
From senescence to scarring: Exploring TGF-β signaling in cellular aging, fibrotic remodeling, and pulmonary fibrosis
Cellular senescence refers to a state of irreversible cell cycle arrest triggered by various stressors, including oxidativ...
The role of transforming growth factor β in cervical carcinogenesis
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Impact of chronic stress on intestinal mucosal immunity in colorectal cancer progression
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Cholecystokinin and gastrin as immune modulating hormones: Implications and applications
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Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation
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Molecular mechanisms of regulation of IL-1 and its receptors
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Ubiquitination in pyroptosis pathway: A potential therapeutic target for sepsis
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JAK inhibitors in immune regulation and treatment of vitiligo
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Glioblastoma-associated macrophages: A key target in overcoming glioblastoma therapeutic resistance
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Adeno-associated virus therapies: Pioneering solutions for human genetic diseases
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Distinct roles of MIF in the pathogenesis of ischemic heart disease
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