Oz Gul O, Cander S, Gul CB, Budak F, Oral B, Ersoy C. Cytokine signal suppressor (SOCS) 1-1478 CA/del gene polymorphism in Turkish patients with polycystic ovary syndrome. J Obstet Gynaecol. 2017;37(7):896–901.
Article CAS PubMed Google Scholar
Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, et al. The androgen excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2009;91(2):456–88.
Govahi Kakhki F, Sargazi S, Montazerifar F, Majidpour M, Karajibani A, Karajibani M et al. IGF2BP2 and IGFBP3 genotypes, haplotypes, and genetic models studies in Polycystic Ovary Syndrome. J Clin Lab Anal. 2024:e25021.
Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106(1):6–15.
Moran L, Teede H. Metabolic features of the reproductive phenotypes of polycystic ovary syndrome. Hum Reprod Update. 2009;15(4):477–88.
Article CAS PubMed Google Scholar
Shirani M, Nouri M, Askari G. Effect of N-acetylcysteine supplementation on polycystic ovary syndrome (PCOS) in infertile women: a systematic review of clinical trials. Clin Excellence. 2019;8(3):1–10.
Biglari-Zadeh G, Sargazi S, Mohammadi M, Ghasemi M, Majidpour M, Saravani R et al. Relationship between genetic polymorphisms in Cell Cycle Regulatory Gene TP53 and polycystic ovarian syndrome: a case–control study and in Silico Analyses. Biochem Genet. 2023:1–23.
Rakhshani Nejad A, Sargazi S, Ghasemi M, Samareh Moosavi S, Heidari Nia M, Saravani R. Association study to evaluate Foxo1 and Foxo3 gene polymorphisms in polycystic ovary syndrome: a preliminary case–control study and in silico analysis. Mol Biol Rep. 2023;50(4):3569–80.
Article CAS PubMed Google Scholar
Rudnicka E, Suchta K, Grymowicz M, Calik-Ksepka A, Smolarczyk K, Duszewska AM, et al. Chronic low grade inflammation in pathogenesis of PCOS. Int J Mol Sci. 2021;22(7):3789.
Article CAS PubMed PubMed Central Google Scholar
Duleba AJ, Dokras A. Is PCOS an inflammatory process? Fertil Steril. 2012;97(1):7–12.
Article CAS PubMed PubMed Central Google Scholar
Guo F, Gong Z, Fernando T, Zhang L, Zhu X, Shi Y. The lipid profiles in different characteristics of women with PCOS and the interaction between dyslipidemia and metabolic disorder states: a retrospective study in Chinese population. Front Endocrinol. 2022;13:892125.
Abraham Gnanadass S, Divakar Prabhu Y, Valsala Gopalakrishnan A. Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update. Arch Gynecol Obstet. 2021;303(3):631–43.
Article CAS PubMed Google Scholar
Rostamtabar M, Esmaeilzadeh S, Tourani M, Rahmani A, Baee M, Shirafkan F, et al. Pathophysiological roles of chronic low-grade inflammation mediators in polycystic ovary syndrome. J Cell Physiol. 2021;236(2):824–38.
Article CAS PubMed Google Scholar
Lamana A, Villares R, Seoane IV, Andrés N, Lucas P, Emery P, et al. Identification of a human SOCS1 polymorphism that predicts rheumatoid arthritis severity. Front Immunol. 2020;11:1336.
Article CAS PubMed PubMed Central Google Scholar
Shao S, Wang H, Shao W, Liu N. miR-199a-5p stimulates ovarian granulosa cell apoptosis in polycystic ovary syndrome. J Mol Endocrinol. 2020;65(4):187–201.
Article CAS PubMed Google Scholar
Wang H, Feng X, Wang T, Pan J, Zheng Z, Su Y, et al. Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats. Gen Comp Endocrinol. 2023;330:114138.
Article CAS PubMed Google Scholar
Cooney RN. Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway. Shock. 2002;17(2):83–90.
Hirschfield G, Xie G, Lu E, Sun Y, Juran B, Chellappa V, et al. Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes. Genes Immun. 2012;13(4):328–35.
Article CAS PubMed PubMed Central Google Scholar
Chen S-S, Wu W-Z, Zhang Y-P, Huang W-J. Gene polymorphisms of SOCS1 and SOCS2 and acute lymphoblastic leukemia. Eur Rev Med Pharmacol Sci. 2020;24(10).
Zhang P, Li F, Li N, Zhu Q, Yang C, Han Q, et al. Genetic variations of SOCS1 are associated with chronic hepatitis B virus infection. Hum Immunol. 2014;75(8):709–14.
Article CAS PubMed Google Scholar
Lamana A, Villares R, Lucas P, Emery P, Vital EM, Marquez A, et al. Identification of a human SOCS1 polymorphism that predicts rheumatoid arthritis severity. Front Immunol. 2020;11:519280.
Tuncel FC, Serin I, Pehlivan S, Oyaci Y, Pehlivan M. Epigenetic and genetic investigation of SOCS-1 gene in patients with multiple myeloma. Blood Res. 2022;57(4):250.
Article CAS PubMed PubMed Central Google Scholar
Paeiz H, Salehi Z, Mashayekhi F, Saeidi Saedi H, Mirzanejad L. The importance of SOCS1 – 1478 CA/del polymorphism and expression in breast cancer: a case–control study in the north of Iran. Breast Cancer Res Treat. 2023;202(2):389–95.
Article CAS PubMed Google Scholar
Ma Q, Liu N, Zhang R, Li X, Zhang H, Li Z, et al. A novel association of the suppressor of cytokine signaling 1 (SOCS1) gene polymorphisms in ischemic stroke patients. Neuromol Med. 2016;18:573–80.
Vargas-Alarcon G, Posadas-Sanchez R, Posadas-Romero C, Gonzalez-Salazar C, Cardoso-Saldaña G, Martinez-Rios MA, et al. Association of the suppressor of cytokine signaling 1 (SOCS1) gene polymorphisms with acute coronary syndrome in Mexican patients. Mol Immunol. 2014;62(1):137–41.
Article CAS PubMed Google Scholar
Harada M, Nakashima K, Hirota T, Shimizu M, Doi S, Fujita K, et al. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am J Respir Cell Mol Biol. 2007;36(4):491–6.
Article CAS PubMed Google Scholar
Guedes RA, Planello AC, Andia DC, De Oliveira NF, de Souza AP. Association of SOCS1 – 820 (rs33977706) gene polymorphism with chronic periodontitis: a case–control study in brazilians. Meta Gene. 2015;5:124–8.
Article PubMed PubMed Central Google Scholar
ESHRE TR, Group A-SPCW. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81(1):19–25.
Gaaib JN, Nassief AF, Al-Assi A. Simple salting-out method for genomic DNA extraction from whole blood. Tikrit J Pure Sci. 2011;16(2):1813–662.
El-Mazny A, Abou-Salem N, El-Sherbiny W, El-Mazny A. Insulin resistance, dyslipidemia, and metabolic syndrome in women with polycystic ovary syndrome. Int J Gynecol Obstet. 2010;109(3):239–41.
Jin H-J, Jung S, DebRoy AR, Davuluri RV. Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer. Oncotarget. 2016;7(34):54616.
Article PubMed PubMed Central Google Scholar
Roos D, de Boer M. Mutations in cis that affect mRNA synthesis, processing and translation. Biochim et Biophys Acta (BBA)-Molecular Basis Disease. 2021;1867(9):166166.
Giacomini KM, Brett CM, Altman RB, Benowitz N, Dolan M, Flockhart D, et al. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin Pharmacol Ther. 2007;81(3):328–45.
Article CAS PubMed Google Scholar
Steri M, Idda ML, Whalen MB, Orrù V. Genetic variants in mRNA untranslated regions. Wiley Interdisciplinary Reviews: RNA. 2018;9(4):e1474.
Galluzzo A, Amato MC, Giordano C. Insulin resistance and polycystic ovary syndrome. Nutr Metabolism Cardiovasc Dis. 2008;18(7):511–8.
Comments (0)