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Particulate matter-induced gene expression patterns in human-derived cells based on 11 public gene expression datasets
Particulate matter-induced gene expression patterns in human-derived cells based on 11 public gene expression datasets
Exposure to particulate matter (PM) and house dust mite (HDM) can change the expression patterns of inflammation-, oxidati...
eEF1A1 regulates the expression and alternative splicing of genes associated with Parkinson’s disease in U251 cells
eEF1A1 regulates the expression and alternative splicing of genes associated with Parkinson’s disease in U251 cells
Eukaryotic elongation factor 1A1 (eEF1A1) is an RNA-binding protein that is associated with PARK2 activity in cells, sugge...
Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers
Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers
The Bradybaenidae snail Karaftohelix adamsi is endemic to Korea, with the species tracked from Island Ulleung in North Gye...
Negative regulation of HDAC3 transcription by histone acetyltransferase TIP60 in colon cancer
Negative regulation of HDAC3 transcription by histone acetyltransferase TIP60 in colon cancer
Colon cancer is the third most common cancer globally. The expression of histone deacetylase 3 (HDAC3) is upregulated, whe...
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells
The apoptosis-resistant pulmonary arterial endothelial cells (PAECs) are known to be major players in the pulmonary remode...
A study on construction of a prognosis model for liver cancer based on analgesic targets and screening therapeutic drugs
A study on construction of a prognosis model for liver cancer based on analgesic targets and screening therapeutic drugs
Liver cancer is one of the most malignant liver diseases in the world, and the 5-year survival rate of such patients is lo...
Molecular characterization of positively selected genes contributing aquatic adaptation in marine mammals
Molecular characterization of positively selected genes contributing aquatic adaptation in marine mammals
Marine mammals, which have evolved independently into three distinct lineages, share common physiological features that co...
MicroRNA 429 regulates MMPs expression by modulating TIMP2 expression in colon cancer cells and inflammatory colitis
MicroRNA 429 regulates MMPs expression by modulating TIMP2 expression in colon cancer cells and inflammatory colitis
In a previous study, we found that the expression of microRNA 429 (MIR429) was decreased in dextran sodium sulfate (DSS)-i...
In silico identification and expression analysis of superoxide dismutases in Tenebrio molitor
In silico identification and expression analysis of superoxide dismutases in Tenebrio molitor
Insects encounter various environmental stresses, in response to which they generate reactive oxygen species (ROS). Supero...
Immune micro-environment analysis and drug screening for ovarian endometriosis
Immune micro-environment analysis and drug screening for ovarian endometriosis
Patients of ovary endometriosis have an abnormal immune micro-environment, leading to endometrial tissue that from retrogr...
A pan-cancer analysis unveiling the function of NR4A family genes in tumor immune microenvironment, prognosis, and drug response
A pan-cancer analysis unveiling the function of NR4A family genes in tumor immune microenvironment, prognosis, and drug response
NR4A family genes play crucial roles in cancers. However, the role of NR4A family genes in cancers remains paradoxical as ...
Actn2 defects accelerates H9c2 hypertrophy via ERK phosphorylation under chronic stress
Actn2 defects accelerates H9c2 hypertrophy via ERK phosphorylation under chronic stress
In humans, ACTN2 mutations are identified as highly relevant to a range of cardiomyopathies such as DCM and HCM, while the...
Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population
Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population
Colorectal cancer (CRC) is the 3rd most common cancer in the world and colonic carcinogenesis is a multifactorial disease ...
Genome-wide identification of cold shock proteins (CSPs) in sweet cherry (Prunus avium L.) and exploring the differential responses of PavCSP1 and PavCSP3 to low temperature and salt stress
Genome-wide identification of cold shock proteins (CSPs) in sweet cherry (Prunus avium L.) and exploring the differential responses of PavCSP1 and PavCSP3 to low temperature and salt stress
Cold shock proteins (CSPs) are ubiquitous nucleic acid-binding proteins involved in growth, development, and stress respon...
Heterogeneity of hepatocellular carcinoma that responds differently to combination therapy with TACE and Sorafenib as determined by digital spatial gene expression profiling
Heterogeneity of hepatocellular carcinoma that responds differently to combination therapy with TACE and Sorafenib as determined by digital spatial gene expression profiling
The combination of Sorafenib and transcatheter arterial chemoembolization (TACE) exhibits limited efficacy in the treatmen...
A novel compound heterozygous mutation of UFC1 in a patient with neurodevelopmental disorder
A novel compound heterozygous mutation of UFC1 in a patient with neurodevelopmental disorder
Neurodevelopmental disorders (NDDs) encompass a diverse group of disorders characterized by impaired cognition, behavior, ...
Analysis of single-cell transcriptome data from a mouse model implicates protein synthesis dysfunction in schizophrenia
Analysis of single-cell transcriptome data from a mouse model implicates protein synthesis dysfunction in schizophrenia
Schizophrenia is a mental disorder that causes considerable morbidity, whose risk largely results from genetic factors. Se...
Transposable elements contribute to tissue-specific gene regulation in humans
Transposable elements contribute to tissue-specific gene regulation in humans
Transposable elements (TEs) contribute to approximately half of the human genome, and along with many other functions, the...
Epigenetic regulation of HERVs: Implications for cancer immunotherapy
Epigenetic regulation of HERVs: Implications for cancer immunotherapy
Human endogenous retroviruses (HERVs), integrated into the human genome during primate evolution, constitute approximately...
Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression
Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression
Breast cancer type 1 susceptibility protein/breast cancer type 2 susceptibility protein-containing complex subunit 3 (BRCC...
The effect of canagliflozin on gut microbiota and metabolites in type 2 diabetic mice
The effect of canagliflozin on gut microbiota and metabolites in type 2 diabetic mice
Sodium glucose cotransporter 2 inhibitor (SGLT2i) represent a new type of hypoglycemic medicine that can cause massive los...
Whole genome sequencing of mouse lines divergently selected for fatness (FLI) and leanness (FHI) revealed several genetic variants as candidates for novel obesity genes
Whole genome sequencing of mouse lines divergently selected for fatness (FLI) and leanness (FHI) revealed several genetic variants as candidates for novel obesity genes
Analysing genomes of animal model organisms is widely used for understanding the genetic basis of complex traits and disea...
Identification and characterization of Acinetobacter nosocomialis BfmRS, two-component regulatory system, essential for biofilm development
Identification and characterization of Acinetobacter nosocomialis BfmRS, two-component regulatory system, essential for biofilm development
Biofilm development by bacteria is considered to be an essential stage in the bacterial infection. Acinetobacter nosocomia...
Genome constitution and evolution of Elymus atratus (Poaceae: Triticeae) inferred from cytogenetic and phylogenetic analysis
Genome constitution and evolution of Elymus atratus (Poaceae: Triticeae) inferred from cytogenetic and phylogenetic analysis
Elymus atratus (Nevski) Hand.-Mazz. is perennial hexaploid wheatgrass. It was assigned to the genus Elymus L. sensu strict...
Whole transcriptome mapping reveals the lncRNA regulatory network of TFP5 treatment in diabetic nephropathy
Whole transcriptome mapping reveals the lncRNA regulatory network of TFP5 treatment in diabetic nephropathy
TFP5 is a Cdk5 inhibitor peptide, which could restore insulin production. However, the role of TFP5 in diabetic nephropath...
In silico identification and expression analyses of peroxidases in Tenebrio molitor
In silico identification and expression analyses of peroxidases in Tenebrio molitor
Human advancements in agriculture, urbanization, and industrialization have led to various forms of environmental pollutio...
Population genetics reveals new introgression in the nucleus herd of min pigs
Population genetics reveals new introgression in the nucleus herd of min pigs
Min pigs are a unique genetic resource among local pig breeds in China. They have more excellent characteristics in cold a...
Clinical report and genetic analysis of a novel variant in ZMIZ1 causing neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies in a Chinese family
Clinical report and genetic analysis of a novel variant in ZMIZ1 causing neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies in a Chinese family
Neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies (NEDDFSA) is a rare and phenotypically v...
Bioinformatics analysis and experimental validation reveal that CDC20 overexpression promotes bladder cancer progression and potential underlying mechanisms
Bioinformatics analysis and experimental validation reveal that CDC20 overexpression promotes bladder cancer progression and potential underlying mechanisms
Bladder cancer is a prevalent malignancy. CDC20, a pivotal cell cycle regulator gene, plays a significant role in tumour c...
Childhood-related neural genotype–phenotype in ATP1A3 mutations: comprehensive analysis
Childhood-related neural genotype–phenotype in ATP1A3 mutations: comprehensive analysis
ATP1A3 is a gene that encodes the ATPase Na + /K + transporting subunit alpha-3 isoenzyme that is ...
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