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Corrigendum: Comprehensive analysis of the prognostic and immunological role of PAFAH1B in pan-cancer
Corrigendum: Comprehensive analysis of the prognostic and immunological role of PAFAH1B in pan-cancer
Corrigendum on: Yuan Y, Jiang X, Tang L, Wang J, Duan L. Comprehensive Analysis of the Prognostic and Immunological Role o...
Exploration of phytoconstituents of Medhya Rasayana herbs to identify potential inhibitors for cerebroside sulfotransferase through high-throughput screening
Exploration of phytoconstituents of Medhya Rasayana herbs to identify potential inhibitors for cerebroside sulfotransferase through high-throughput screening
Cerebroside sulfotransferase (CST) is a key enzyme in sulfatide biosynthesis and regulation of the myelin sheath in the ne...
How lactate affects immune strategies in lymphoma
How lactate affects immune strategies in lymphoma
Tumor cells undergo metabolic reprogramming through shared pathways, resulting in a hypoxic, acidic, and highly permeable ...
Editorial: Celebrating women’s contribution to protein folding, misfolding, and degradation in honor of Susan Lindquist (1949–2016)
David H. Koch Institute for Integrative Cancer Research, and a biology professor at MIT for the rest of her career.Susan L...
Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy
Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy
Platelet-derived growth factor receptor beta (PDGFRβ) belongs to the receptor tyrosine kinase (RTK) protein family and is ...
Integrated analysis of abnormal metabolic homeostasis for decoding tumor microenvironment
Integrated analysis of abnormal metabolic homeostasis for decoding tumor microenvironment
In 2023 and 2024, Nature published a series of crucial roles of metabolic abnormalities in tumor occurrence, development, ...
Editorial: Bio-nanomaterials and systems for enhanced bioimaging in biomedical applications
This editorial provides an overview of the contributions to the Frontiers Research Topic "Bio-Nanomaterials and S...
Profiling of the serum MiRNAome in pediatric egyptian patients with wilms tumor
Profiling of the serum MiRNAome in pediatric egyptian patients with wilms tumor
Wilms tumor (WT) is a pediatric kidney cancer associated with poor outcomes in patients with unfavorable histological feat...
Genome-wide identification and analysis of the HD-Zip transcription factor family in oats
1 IntroductionOats (Avena sativa L.) are an annual herbaceous plant of the oat genus (Avena) in the Poaceae family, and ar...
Crotonylation modification and its role in diseases
1 IntroductionPost-translational modifications (PTMs) of proteins significantly impact their biological functions, includi...
Anhydrous microwave synthesis as efficient method for obtaining model advanced glycation end-products
1 IntroductionAdvanced glycation end-products (AGEs) are products of the non-enzymatic reaction of proteins and reducing s...
Differential expression of ferroptosis-related proteins in urinary exosomes: potential indicators for monitoring acute gout attack
1 IntroductionGout is an inflammatory disease caused by high levels of uric acid in the blood, leading to various forms of...
Dynamics simulations of hypoxia inducible factor-1 regulatory network in cancer using formal verification techniques
1 IntroductionCancer cell growth is a fundamental biological process characterized by cell proliferation, and an increase ...
AKK-derived outer membrane vesicles alleviate indomethacin-induced mucin secretion reduction in LS174T cells by inhibiting endoplasmic reticulum stress
1 IntroductionExtracellular vesicles (EVs) are lipid bilayer-enclosed structures that carry a variety of biomolecules, inc...
Crystallographic insights into lipid-membrane protein interactions in microbial rhodopsins
IntroductionLipid-membrane protein (MP) interactions are known to predetermine the MP structure. The alteration of the lip...
Proteomics analysis of extracellular vesicles for biomarkers of autism spectrum disorder
1 IntroductionAutism spectrum disorder (ASD) is a complex neurodevelopmental condition, characterized by stereotyped repet...
Esophageal adenocarcinoma models: a closer look
1 IntroductionEsophageal cancer (EC) is the tenth most common cancer worldwide and the sixth leading cause of cancer death...
Editorial: Machine learning approaches for differential diagnosis, prognosis, prevention, and treatment of digestive system disorders
Digestive System Diseases (DSD) primarily include diseases of the gastrointestinal tract as well as those affecting organs...
Hydrogen peroxide disrupts the regulatory pathway of saliva secretion in two salivary acinar rat cell lines
IntroductionSaliva is produced by the major salivary glands, including the parotid glands (PG), submandibular glands (SMG)...
Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake
IntroductionFerroptosis is a regulated form of programmed cell death that is mechanistically distinct from other pathways ...
Towards interpretable Cryo-EM: disentangling latent spaces of molecular conformations
Towards interpretable Cryo-EM: disentangling latent spaces of molecular conformations
Molecules are essential building blocks of life and their different conformations (i.e., shapes) crucially determine the f...
Understanding the impact of in vitro transcription byproducts and contaminants
Understanding the impact of in vitro transcription byproducts and contaminants
The success of messenger (m)RNA-based vaccines against SARS-CoV-2 during the COVID-19 pandemic has led to rapid growth and...
Metabolomics highlights biochemical perturbations occurring in the kidney and liver of mice administered a human dose of colistin
Metabolomics highlights biochemical perturbations occurring in the kidney and liver of mice administered a human dose of colistin
Introduction: Colistin (CMS) is used for the curation of infections caused by multidrug-resistant bacteria. CMS is constra...
Inactive metallopeptidase homologs: the secret lives of pseudopeptidases
Inactive metallopeptidase homologs: the secret lives of pseudopeptidases
Inactive enzyme homologs, or pseudoenzymes, are proteins, found within most enzyme families, that are incapable of perform...
Gestational diabetes mellitus: Impacts on fetal neurodevelopment, gut dysbiosis, and the promise of precision medicine
Gestational diabetes mellitus: Impacts on fetal neurodevelopment, gut dysbiosis, and the promise of precision medicine
Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting approximately 16.5% of pregnancies worldwide ...
Use of logit transformation within statistical analyses of experimental results obtained as proportions: example of method validation experiments and EQA in flow cytometry
Use of logit transformation within statistical analyses of experimental results obtained as proportions: example of method validation experiments and EQA in flow cytometry
In laboratory medicine, measurement results are often expressed as proportions of concentrations or counts. These proporti...
RNAi-dependent expression of sperm genes in ADL chemosensory neurons is required for olfactory responses in Caenorhabditis elegans
RNAi-dependent expression of sperm genes in ADL chemosensory neurons is required for olfactory responses in Caenorhabditis elegans
Environmental conditions experienced early in the life of an animal can result in gene expression changes later in its lif...
Bibliometric analysis on CRISPR/Cas: a potential Sherlock Holmes for disease detection
Bibliometric analysis on CRISPR/Cas: a potential Sherlock Holmes for disease detection
CRISPR has revolutionized illness detection by using precision gene editing to identify specific sequences in recent years...
Carnitine O-octanoyltransferase (CROT) deficiency in mice leads to an increase of omega-3 fatty acids
Carnitine O-octanoyltransferase (CROT) deficiency in mice leads to an increase of omega-3 fatty acids
Introduction: Carnitine O-octanoyltransferase (CROT) is a well-established peroxisomal enzyme involved in liver fatty acid...
Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication
Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication
Extracellular vesicles (EVs) serve as messengers for intercellular communication, yet the precise mechanisms by which reci...
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