SCI时时刷

search
+
The association of TNF-alpha secretion and mtDNA copy number in CD14+ monocytes of patients with obesity and CHD
The association of TNF-alpha secretion and mtDNA copy number in CD14+ monocytes of patients with obesity and CHD
IntroductionMitochondrial dysfunction may be one of the causes of inflammatory activation of monocytes and macrophages, wh...
Editorial: Heparan sulfate-binding proteins in health and disease
Editorial: Heparan sulfate-binding proteins in health and disease
Professor Robert J. Linhardt, whose contributions have left an indelible mark. Recognized globally for his pioneering rese...
Genetic correlation between circulating metabolites and chalazion: a two-sample Mendelian randomization study
Genetic correlation between circulating metabolites and chalazion: a two-sample Mendelian randomization study
Background: Lipid metabolism disorders were observationally associated with chalazion, but the causality of the related ci...
An automatic diagnosis model of otitis media with high accuracy rate using transfer learning
An automatic diagnosis model of otitis media with high accuracy rate using transfer learning
Introduction: Chronic Suppurative Otitis Media (CSOM) and Middle Ear Cholesteatoma are two common chronic otitis media dis...
Serum proteomic profiling of precancerous gastric lesions and early gastric cancer reveals signatures associated with systemic inflammatory response and metaplastic differentiation
Serum proteomic profiling of precancerous gastric lesions and early gastric cancer reveals signatures associated with systemic inflammatory response and metaplastic differentiation
The noninvasive detection technique using serum for large-scale screening is useful for the early diagnosis of gastric can...
The underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma
The underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma
The consistent notion holds that hepatocellular carcinoma (HCC) initiation, progression, and clinical treatment failure tr...
Simple Scattering: Lipid nanoparticle structural data repository
Simple Scattering: Lipid nanoparticle structural data repository
Lipid nanoparticles (LNPs) are being intensively researched and developed to leverage their ability to safely and effectiv...
Prostate fibroblasts and prostate cancer associated fibroblasts exhibit different metabolic, matrix degradation and PD-L1 expression responses to hypoxia
Prostate fibroblasts and prostate cancer associated fibroblasts exhibit different metabolic, matrix degradation and PD-L1 expression responses to hypoxia
Fibroblasts are versatile cells that play a major role in wound healing by synthesizing and remodeling the extracellular m...
CyaA translocation across eukaryotic cell membranes
CyaA translocation across eukaryotic cell membranes
The adenylate cyclase (CyaA) toxin is a major virulence factor produced by Bordetella pertussis, the causative agent of wh...
Editorial: Advanced functional nanomaterials for diagnosis, bioimaging, drug delivery and therapeutics
Editorial: Advanced functional nanomaterials for diagnosis, bioimaging, drug delivery and therapeutics
In the healthcare domain, nanomaterials play a pivotal role in simultaneous disease detection and treatment, addressing co...
Therapeutic potential of tyrosine-protein kinase MET in osteosarcoma
Therapeutic potential of tyrosine-protein kinase MET in osteosarcoma
Osteosarcoma, the most prevalent primary bone tumor in children and young adults, can often be successfully treated with s...
Modeling of noncovalent inhibitors of the papain-like protease (PLpro) from SARS-CoV-2 considering the protein flexibility by using molecular dynamics and cross-docking
Modeling of noncovalent inhibitors of the papain-like protease (PLpro) from SARS-CoV-2 considering the protein flexibility by using molecular dynamics and cross-docking
The papain-like protease (PLpro) found in coronaviruses that can be transmitted from animals to humans is a critical targe...
Longitudinal analysis of 20 Years of external quality assurance schemes for PCR/NAAT-based bacterial genome detection in diagnostic testing
Longitudinal analysis of 20 Years of external quality assurance schemes for PCR/NAAT-based bacterial genome detection in diagnostic testing
Background:Quality control (QC), quality assurance, and standardization are crucial for modern diagnostic testing in the f...
Evaluation of Adenanthera pavonina-derived compounds against diabetes mellitus: insight into the phytochemical analysis and in silico assays
Evaluation of Adenanthera pavonina-derived compounds against diabetes mellitus: insight into the phytochemical analysis and in silico assays
Adenanthera pavonina is a medicinal plant with numerous potential secondary metabolites showing a significant level of ant...
Effects of saponins Rb1 and Re in American ginseng combined intervention on immune system of aging model
Effects of saponins Rb1 and Re in American ginseng combined intervention on immune system of aging model
Aging is a major risk factor for the development of many pathological processes, such as reduced immunity, cancer, cardiov...
GEO dataset mining analysis reveals novel Staphylococcus aureus virulence gene regulatory networks and diagnostic targets in mice
GEO dataset mining analysis reveals novel Staphylococcus aureus virulence gene regulatory networks and diagnostic targets in mice
Staphylococcus (S.) aureus infection is a serious, worldwide health concern, particularly in many communities and hospital...
The coordinated activities of collagen VI and XII in maintenance of tissue structure, function and repair: evidence for a physical interaction
The coordinated activities of collagen VI and XII in maintenance of tissue structure, function and repair: evidence for a physical interaction
Collagen VI and collagen XII are structurally complex collagens of the extracellular matrix (ECM). Like all collagens, typ...
Editorial: Functions, working mechanisms, and regulation of rotary ATPases and Ductin proteins
Editorial: Functions, working mechanisms, and regulation of rotary ATPases and Ductin proteins
The rotary mechanism of the ion-transporting F-, V-and A-type ATPases is of great interest to the molecular bio-sciences. ...
Benchmarking antibody clustering methods using sequence, structural, and machine learning similarity measures for antibody discovery applications
Benchmarking antibody clustering methods using sequence, structural, and machine learning similarity measures for antibody discovery applications
Antibodies are proteins produced by our immune system that have been harnessed as biotherapeutics. The discovery of antibo...
Electrophysiological properties and structural prediction of the SARS-CoV-2 viroprotein E
Electrophysiological properties and structural prediction of the SARS-CoV-2 viroprotein E
COVID-19, the infectious disease caused by the most recently discovered coronavirus SARS- CoV-2, has caused millions of si...
Formation of dsRNA by-products during in vitro transcription can be reduced by using low steady-state levels of UTP
Formation of dsRNA by-products during in vitro transcription can be reduced by using low steady-state levels of UTP
Introduction: Exogeneous messenger ribonucleic acid (mRNA) can be used as therapeutic and preventive medication. However, ...
Editorial: Molecular determinants of protein assemblies in health and disease, Volume II
Editorial: Molecular determinants of protein assemblies in health and disease, Volume II
that underlie the production, reversibility, and turnover of dynamic biomolecular condensates and static protein aggregate...
A prognostic model based on prognosis-related ferroptosis genes for patients with acute myeloid leukemia
A prognostic model based on prognosis-related ferroptosis genes for patients with acute myeloid leukemia
Background: Acute myeloid leukemia (AML) is a heterogeneous disorder with an unpredictable prognosis. Ferroptosis, the iro...
The elucidation of the multimodal action of the investigational anti-Candida lipopeptide (AF4) lead from Bacillus subtilis
The elucidation of the multimodal action of the investigational anti-Candida lipopeptide (AF4) lead from Bacillus subtilis
Background:Candida species are the main etiological agents for candidiasis, and Candida albicans are the most common infec...
Crosstalk of ferroptosis and oxidative stress in infectious diseases
Crosstalk of ferroptosis and oxidative stress in infectious diseases
Ferroptosis is a type of programmed cell death that pathogens can leverage to enhance their replication, transmission, and...
Evidence of DISC1 as an arsenic binding protein and implications regarding its role as a translational activator
Evidence of DISC1 as an arsenic binding protein and implications regarding its role as a translational activator
Disrupted-in-schizophrenia-1 (DISC1) is a scaffolding protein that plays a pivotal role in orchestrating signaling pathway...
Tools and tactics to define specificity of metabolic chemical reporters
Tools and tactics to define specificity of metabolic chemical reporters
Metabolic chemical reporters (MCRs) provide easily accessible means to study glycans in their native environments. However...
ASCA-related antibodies in the blood sera of healthy donors and patients with colorectal cancer: characterization with oligosaccharides related to Saccharomyces cerevisiae mannan
ASCA-related antibodies in the blood sera of healthy donors and patients with colorectal cancer: characterization with oligosaccharides related to Saccharomyces cerevisiae mannan
Mannans are polysaccharide antigens expressed on the cell wall of different fungal species including Saccharomyces cerevis...
Misfolding of fukutin-related protein (FKRP) variants in congenital and limb girdle muscular dystrophies
Misfolding of fukutin-related protein (FKRP) variants in congenital and limb girdle muscular dystrophies
Fukutin-related protein (FKRP, MIM ID 606596) variants cause a range of muscular dystrophies associated with hypo-glycosyl...
Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort
Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort
Type 2 diabetes mellitus (T2DM) can be multifactorial where both genetics and environmental factors play a role. We aimed ...
阅读更多
format_indent_increase