Thrombopoiesis and Androgen Biosynthesis in Patients with Adrenal Cortex Tumors

Klinicheskie rekomendatsii po raku kory nadpochechnikov (Adrenokortikal’nyi rak) (Clinical Guidelines for Adrenal Cortex Cancer (Adrenocortical Cancer)), Mel’nichenko, G.A., Alekseev, B.Ya., Bel’tsevich, D.G., et al., Eds., Moscow, 2020.

Terzolo, M. and Fassnacht, M., ENDOCRINE TUMOURS: Our experience with the management of patients with non-metastatic adrenocortical carcinoma, Eur. J. Endocrinol., 2022, vol. 187, no. 3, pp. R27–R40.

CAS  PubMed  Google Scholar 

Elhassan, Y.S. et al., S-GRAS score for prognostic classification of adrenocortical carcinoma: An international, multicenter ENSAT study, Eur. J. Endocrinol., 2022, vol. 186, no. 1, pp. 25–36.

CAS  Google Scholar 

Catani, M.V. et al., The “Janus face” of platelets in cancer, Int. J. Mol. Sci., 2020, vol. 21, no. 3, p. 788.

CAS  PubMed  PubMed Central  Google Scholar 

Cao, W. et al., Prognostic role of pretreatment thrombocytosis on survival in patients with cervical cancer: A systematic review and meta-analysis, World J. Surg. Oncol., 2019, vol. 17, no. 1, p. 132.

PubMed  PubMed Central  Google Scholar 

Zhang, X. and Ran, Y., Prognostic role of elevated platelet count in patients with lung cancer: A systematic review and meta-analysis, Int. J. Clin. Exp. Med., 2015, vol. 15, no. 8 (4), pp. 5379–5387.

Gu, D. and Szallasi, A., Thrombocytosis portends adverse prognosis in colorectal cancer: A meta-analysis of 5,619 patients in 16 individual studies, Anticancer Res., 2017, vol. 37, no. 9, pp. 4717–4726.

PubMed  Google Scholar 

Stone, R.L., et al., Paraneoplastic thrombocytosis in ovarian cancer, N. Engl. J. Med., 2012, vol. 366, no. 7, pp. 610–618.

CAS  PubMed  PubMed Central  Google Scholar 

Braun, A., et al., Platelet-cancer interplay: Molecular mechanisms and new therapeutic avenues, Front. On-col., 2021, vol. 11, p. 665534.

CAS  Google Scholar 

Duvernay, M.T., et al., Contributions of protease-activated receptors PAR1 and PAR4 to thrombin-induced GPIIbIIIa activation in human platelets, Mol. Pharmacol., 2017, vol. 91, no. 1, pp. 39–47.

CAS  PubMed  PubMed Central  Google Scholar 

Roşca, A.E., et al., Effects of exogenous androgens on platelet activity and their thrombogenic potential in supraphysiological administration: A literature review, J. Clin. Med., 2021, vol. 10, no. 1, p. 147.

PubMed  PubMed Central  Google Scholar 

Khetawat, G., et al., Human megakaryocytes and platelets contain the estrogen receptor β and androgen receptor (AR): Testosterone regulates AR expression, Blood, 2000, vol. 95, no. 7, pp. 2289–2296.

CAS  PubMed  Google Scholar 

Milewich, L. and Whisenant, M.G., Metabolism of androstenedione by human platelets: A source of potent androgens, J. Clin. Endocrinol. Metab., 1982, vol. 54, no. 5, pp. 969–974.

CAS  PubMed  Google Scholar 

Zaslavsky, A.B., et al., Platelet-synthesized testosterone in men with prostate cancer induces androgen receptor signaling, Neoplasia, 2015, vol. 17, no. 6, pp. 490–496.

CAS  PubMed  PubMed Central  Google Scholar 

Akhvlediani, N.D., Babaev, M.U., and Solov’ev, V.V., Evolution of concepts on the role of testosterone in prostate cancer. A literature review, Androl. Genital’naya Khir., 2022, vol. 23, no. 4, pp. 26–35.

Google Scholar 

TNM Classification of Malignant Tumours, Brierley, J.D., Gospodarowicz, M.K., and Wittrkind, C., Eds., Oxford: Blackwell, 2017.

Google Scholar 

Marques, P. et al., Pre-operative serum inflammation-based scores in patients with pituitary adenomas, Pituitary, 2021, vol. 24, no. 3, pp. 334–350.

CAS  PubMed  Google Scholar 

Weiss, L.M., Comparative histologic study of 43 metastasizing and nonmetastasizing adrenocortical tumors, Am. J. Surg. Pathol., 1984, vol. 8, no. 3, pp. 163–169.

CAS  PubMed  Google Scholar 

Velikanova, L.I., Strel’nikova, E.G., Obedkova, E.V., et al., Generation of urinary steroid profiles in patients with adrenal incidentaloma using gas chromatography–mass spectrometry, J. Anal. Chem., 2016, vol. 71, no. 7, pp. 748–754.

Suzuki, A., Takahashi, T., Nakamura, K., Tsuyuoka, R., Okuno, Y., Enomoto, T., Fukumoto, M., and Imura, H., Thrombocytosis in patients with tumors producing colony-stimulating factor, Blood, 1992, vol. 80, no. 8, pp. 2052–2059.

CAS  PubMed  Google Scholar 

Kerkhofs, T.M.A. et al., Diagnostic value of urinary steroid profiling in the evaluation of adrenal tumors, Horm. Cancer, 2015, vol. 6, no. 4, pp. 168–175.

CAS  PubMed  PubMed Central  Google Scholar 

Hong, X. et al., Systemic immune-inflammation index, based on platelet counts and neutrophil−lymphocyte ratio, is useful for predicting prognosis in small cell lung cancer, Tohoku J. Exp. Med., 2015, vol. 236, no. 4, pp. 297–304.

CAS  PubMed  Google Scholar 

Hu, B. et al., Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma, Clin. Cancer Res., 2014, vol. 20, no. 23, pp. 6212–6222.

CAS  PubMed  Google Scholar 

Feng, J.-F., Chen, S., and Yang, X., Systemic immune-inflammation index (SII) is a useful prognostic indicator for patients with squamous cell carcinoma of the esophagus, Medicine, 2017, vol. 96, no. 4, p. e5886.

PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif