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YBX1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma via transcriptional regulation of PLRG1
YBX1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma via transcriptional regulation of PLRG1
Hepatocellular carcinoma (HCC) ranks as the sixth most prevalent cancer worldwide. The epithelial-mesenchymal transition (...
The role of kinesin superfamily proteins in hepatocellular carcinoma
The role of kinesin superfamily proteins in hepatocellular carcinoma
The most prevalent form of primary liver cancer, hepatocellular carcinoma (HCC) poses a significant global health challeng...
Glycolytic pathway analysis and gene expression profiles of combination of aloe vera and paclitaxel on non-small cell lung cancer and breast cancer
Glycolytic pathway analysis and gene expression profiles of combination of aloe vera and paclitaxel on non-small cell lung cancer and breast cancer
The purpose of this study is to enhance the effectiveness of known anticancer medications using natural compounds. The stu...
PARP1 acetylation at K119 is essential in regulating the progression and proliferation of cervical cancer cells
PARP1 acetylation at K119 is essential in regulating the progression and proliferation of cervical cancer cells
Cervical cancer, CC, is one of the malignant cancers in women worldwide. Many studies about the genesis and progression of...
Modulation of the tumor microenvironment in non-muscle-invasive bladder cancer by OncoTherad® (MRB-CFI-1) nanoimmunotherapy: effects on tumor-associated macrophages, tumor-infiltrating lymphocytes, and monoamine oxidases
Modulation of the tumor microenvironment in non-muscle-invasive bladder cancer by OncoTherad® (MRB-CFI-1) nanoimmunotherapy: effects on tumor-associated macrophages, tumor-infiltrating lymphocytes, and monoamine oxidases
Non-muscle-invasive bladder cancer (NMIBC) presents management challenges due to its high recurrence rate and a complex tu...
Personalized oncology in pheochromocytomas and paragangliomas: integrating genetic analysis with machine learning
Personalized oncology in pheochromocytomas and paragangliomas: integrating genetic analysis with machine learning
Pheochromocytomas and paragangliomas (PCCs/PGLs) are uncommon neuroendocrine tumors with a significant genetic tendency. A...
Current evidence on patient precautions for reducing breast cancer-related lymphedema manifestation and progression risks
Current evidence on patient precautions for reducing breast cancer-related lymphedema manifestation and progression risks
Risk management and self-management strategies for breast cancer-related lymphedema (BCRL) must balance best-evidence guid...
Essential components of the maintenance phase of complex decongestive therapy
Essential components of the maintenance phase of complex decongestive therapy
Complex decongestive therapy is the current gold standard for non-surgical clinical lymphedema management and consists of ...
The effect of compression therapies and therapeutic modalities on lymphedema secondary to cancer: a rapid review and evidence map
The effect of compression therapies and therapeutic modalities on lymphedema secondary to cancer: a rapid review and evidence map
The identification of effective therapeutic modalities to manage lymphedema secondary to cancer is a high priority among p...
Recent advancements in cGAS-STING activation, tumor immune evasion, and therapeutic implications
Recent advancements in cGAS-STING activation, tumor immune evasion, and therapeutic implications
The cGAS-STING signaling pathway is indeed a pivotal component of the immune system and serve as a crucial link between in...
Salvianolic acid B inhibits the growth and metastasis of A549 lung cancer cells through the NDRG2/PTEN pathway by inducing oxidative stress
Salvianolic acid B inhibits the growth and metastasis of A549 lung cancer cells through the NDRG2/PTEN pathway by inducing oxidative stress
Salvianolic acid B (Sal B) has demonstrated anticancer activity against various types of cancer. However, the underlying m...
Highlighting the role of long non-coding RNA (LncRNA) in multiple myeloma (MM) pathogenesis and response to therapy
Highlighting the role of long non-coding RNA (LncRNA) in multiple myeloma (MM) pathogenesis and response to therapy
Transcripts longer than 200 nucleotides that are not translated into proteins are known as long non-coding RNAs, or lncRNA...
Multifaceted role of erlotinib in various cancer: nanotechnology intervention, patent landscape, and advancements in clinical trials
Multifaceted role of erlotinib in various cancer: nanotechnology intervention, patent landscape, and advancements in clinical trials
Erlotinib (ELB) is a tyrosine kinase inhibitor that targets the activity of Epidermal Growth Factor Receptor (EGFR) protei...
IRTKS contributes to the malignant progression of cervical cancer cells
IRTKS contributes to the malignant progression of cervical cancer cells
Cervical cancer (CC), one of the most aggressive tumors in women, has high risk rates of recurrence and metastasis. It is ...
Revealing the therapeutic properties of gut microbiota: transforming cancer immunotherapy from basic to clinical approaches
Revealing the therapeutic properties of gut microbiota: transforming cancer immunotherapy from basic to clinical approaches
The immune system plays a pivotal role in the battle against cancer, serving as a formidable guardian in the ongoing fight...
Strategic advancement of E3 ubiquitin ligase in the management of hepatocellular carcinoma
Strategic advancement of E3 ubiquitin ligase in the management of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) presents a significant global health challenge due to its high incidence, poor prognosis, a...
Multifaceted effects of LRP6 in cancer: exploring tumor development, immune modulation and targeted therapies
Multifaceted effects of LRP6 in cancer: exploring tumor development, immune modulation and targeted therapies
Low-density lipoprotein receptor (LDLR)-related protein 6 (LRP6), a member of the LDLR superfamily of cell surface recepto...
Dissecting the multifaceted roles of autophagy in cancer initiation, growth, and metastasis: from molecular mechanisms to therapeutic applications
Dissecting the multifaceted roles of autophagy in cancer initiation, growth, and metastasis: from molecular mechanisms to therapeutic applications
Autophagy is a cytoplasmic defense mechanism that cells use to break and reprocess their intracellular components. This ut...
Interleukin-6 serves as a critical factor in various cancer progression and therapy
Interleukin-6 serves as a critical factor in various cancer progression and therapy
Interleukin-6 (IL-6), a pro-inflammatory cytokine, plays a crucial role in host immune defense and acute stress responses....
Inhibition of STAT3-NF-κB pathway facilitates SSPH I-induced ferroptosis in HepG2 cells
Inhibition of STAT3-NF-κB pathway facilitates SSPH I-induced ferroptosis in HepG2 cells
Hepatocellular carcinoma (HCC), a highly lethal solid tumor, has shown responsiveness to ferroptosis inducers, presenting ...
A study with cancer stem cells and three-dimensional tumoroids: investigation of the combined effects of 5-fluorouracil and doxorubicin in breast cancer
A study with cancer stem cells and three-dimensional tumoroids: investigation of the combined effects of 5-fluorouracil and doxorubicin in breast cancer
The purpose of the present study was in vitro determination of the combined effects of doxorubucin and 5-fluorouracil by 2...
Genipin’s potential as an anti-cancer agent: from phytochemical origins to clinical prospects
Genipin’s potential as an anti-cancer agent: from phytochemical origins to clinical prospects
This comprehensive review delves into the multifaceted aspects of genipin, a bioactive compound derived from medicinal pla...
A drug repurposing study identifies novel FOXM1 inhibitors with in vitro activity against breast cancer cells
A drug repurposing study identifies novel FOXM1 inhibitors with in vitro activity against breast cancer cells
FOXM1, a proto-oncogenic transcription factor, plays a critical role in cancer development and treatment resistance in can...
The role of IL-17 in the pathogenesis and treatment of glioblastoma—an update on the state of the art and future perspectives
The role of IL-17 in the pathogenesis and treatment of glioblastoma—an update on the state of the art and future perspectives
Glioblastoma (GBM) is the most common malignant brain tumor, which, despite significant progress made in the last years in...
Up and away with cervical cancer: IL-29 is a promising cytokine for immunotherapy of cervical cancer due to its powerful upregulation of p18, p27, and TRAILR1
Up and away with cervical cancer: IL-29 is a promising cytokine for immunotherapy of cervical cancer due to its powerful upregulation of p18, p27, and TRAILR1
CC is one of the most common types of cancers in women, and for advanced CC, the median survival is a mere 16.8 months [6]...
Unlocking the ‘ova’-coming power: immunotherapy’s role in shaping the future of ovarian cancer treatment
Unlocking the ‘ova’-coming power: immunotherapy’s role in shaping the future of ovarian cancer treatment
Ovarian cancer is a prominent cancer worldwide with a relatively low survival rate for women diagnosed. Many individuals a...
Regulation of the P53 tumor suppressor gene and the Mcl-2 oncogene expression by an active herbal component delivered through a smart thermo-pH-sensitive PLGA carrier to improve Osteosarcoma treatment
Regulation of the P53 tumor suppressor gene and the Mcl-2 oncogene expression by an active herbal component delivered through a smart thermo-pH-sensitive PLGA carrier to improve Osteosarcoma treatment
Osteosarcoma (OS), a lethal malignancy, has witnessed an escalating incidence rate. Contemporary therapeutic strategies fo...
A therapeutical insight into the correlation between circRNAs and signaling pathways involved in cancer pathogenesis
A therapeutical insight into the correlation between circRNAs and signaling pathways involved in cancer pathogenesis
Pre-messenger RNA molecules are back-spliced to create circular RNAs, which are non-coding RNA molecules. After a thorough...
The combined anti-tumor effects of 5-fluorouracil and neurokinin receptor inhibitor, aprepitant, against colorectal cancer: In vitro and in vivo study
The combined anti-tumor effects of 5-fluorouracil and neurokinin receptor inhibitor, aprepitant, against colorectal cancer: In vitro and in vivo study
Colorectal cancer (CRC) is one of the world’s largest health concerns with growing global incidence and mortality. T...
Selective targeting or reprogramming of intra-tumoral Tregs
Selective targeting or reprogramming of intra-tumoral Tregs
Regulatory T cells (Tregs) are critical immunosuppressive cells that are frequently present in the tumor microenvironment ...
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