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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma
Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma
Neuroblastoma (NB) is a predominantly pediatric cancer with greater than 90% of cases arising in children under the age of...
Advancing glioblastoma treatment by targeting metabolism
Advancing glioblastoma treatment by targeting metabolism
Volume 51, May 2024, 100985Author links open overlay panel, , , , , , AbstractAlterations in cellular metabolism are impor...
ST6GAL1 is associated with poor response to chemoradiation in rectal cancer
ST6GAL1 is associated with poor response to chemoradiation in rectal cancer
Volume 51, May 2024, 100984Author links open overlay panel, , , , , , , AbstractIntroductionColorectal cancer is the third...
PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures
PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures
Gene fusions are common in high-grade serous ovarian cancer (HGSC). Such genetic lesions may promote tumorigenesis, but th...
Disease burden and projection of total and early-onset colorectal cancer in Gulf cooperation council countries from 1990 to 2019
Disease burden and projection of total and early-onset colorectal cancer in Gulf cooperation council countries from 1990 to 2019
BackgroundEarly-onset colorectal cancer (EO-CRC) incidence and prevalence trends in the rise in high income countries, suc...
A synergistic approach for modulating the tumor microenvironment to enhance nano-immunotherapy in sarcomas
A synergistic approach for modulating the tumor microenvironment to enhance nano-immunotherapy in sarcomas
KeywordsMechanotherapeuticsSonopermeationNanomedicineImmune checkpoint inhibitionUltrasoundAbbreviationsTMEtumor microenvi...