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The Challenge of Melanoma Chemoprevention
The Challenge of Melanoma Chemoprevention
AbstractMelanoma is a treatment-resistant cancer of melanocytes. There is a serious unmet need for chemopreventive agents ...
Dietary Pterostilbene for MTA1-Targeted Interception in High-Risk Premalignant Prostate Cancer
Dietary Pterostilbene for MTA1-Targeted Interception in High-Risk Premalignant Prostate Cancer
Prostate cancer remains one of the most prevalent cancers in aging men. Active surveillance subpopulation of patients with...
Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study
Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study
AbstractData from germline testing in unselected patients with hepatobiliary cancers are limited. Identification of germli...
A Randomized Double-blind Placebo-controlled Trial of Oral Aspirin for Protection of Melanocytic Nevi Against UV-induced DNA Damage
A Randomized Double-blind Placebo-controlled Trial of Oral Aspirin for Protection of Melanocytic Nevi Against UV-induced DNA Damage
DNA damage plays a role in ultraviolet (UV)-induced melanoma. We previously showed that aspirin (ASA) can suppress prostag...
The First Lady Presses for Cancer Screening to Get Back On Track
The First Lady Presses for Cancer Screening to Get Back On Track
The First Lady of the United States, Dr. Jill Biden, visited the Hollings Cancer Center at the Medical University of South...
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer Adelaide Young, Wen Bu, Weiyu ...
Composite Score of Healthy Lifestyle Factors and the Risk of Pancreatic Cancer in a Prospective Cohort Study
Composite Score of Healthy Lifestyle Factors and the Risk of Pancreatic Cancer in a Prospective Cohort Study
While the associations between individual lifestyle factors and risk of pancreatic cancer were studied extensively, their ...
Cost Effectiveness of Lung Cancer Screening With Low-Dose CT in Heavy Smokers in China
Cost Effectiveness of Lung Cancer Screening With Low-Dose CT in Heavy Smokers in China
Although lung cancer screening with low-dose CT (LDCT) can reduce lung cancer mortality by 20%, without an appropriate eli...
Reduction in Vaccine HPV Type Infections in a Young Women Group (18-25 Years) Five Years after HPV Vaccine Introduction in Colombia
Reduction in Vaccine HPV Type Infections in a Young Women Group (18-25 Years) Five Years after HPV Vaccine Introduction in Colombia
IntroductionNational human papillomavirus (HPV) vaccination programs have been implemented in many countries with coverage...
The Urgent Need for Expanded Cancer Screening
The Urgent Need for Expanded Cancer Screening
AbstractOn October 20, 2021, I had the privilege of testifying before the House Energy and Commerce Committee, Subcommitte...
Preventing Cervical Cancer Globally: Are We Making Progress?
Preventing Cervical Cancer Globally: Are We Making Progress?
An unacceptable number of women continue to die from cervical cancer around the world each year. Despite established prima...
High-burden Cancers in Middle-income Countries: A Review of Prevention and Early Detection Strategies Targeting At-risk Populations
High-burden Cancers in Middle-income Countries: A Review of Prevention and Early Detection Strategies Targeting At-risk Populations
Cancer incidence is rising in low- and especially middle-income countries (MIC), driven primarily by four high-burden canc...
Environmental Enrichment Mitigates Age-Related Metabolic Decline and Lewis Lung Carcinoma Growth in Aged Female Mice
Environmental Enrichment Mitigates Age-Related Metabolic Decline and Lewis Lung Carcinoma Growth in Aged Female Mice
1Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, Ohio.2The Ohio State...
Uptake and Predictors of Opportunistic Salpingectomy for Ovarian Cancer Risk Reduction in the United States
Uptake and Predictors of Opportunistic Salpingectomy for Ovarian Cancer Risk Reduction in the United States
Evidence suggesting that high-grade serous ovarian cancers originate in the fallopian tubes has led to the emergence of op...
Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids
Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids
Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids Matthew...
Predicting Progression of Low-Grade Oral Dysplasia Using Brushing-Based DNA Ploidy and Chromatin Organization Analysis
Predicting Progression of Low-Grade Oral Dysplasia Using Brushing-Based DNA Ploidy and Chromatin Organization Analysis
Most oral cancers arise from oral potentially malignant lesions, which show varying grades of dysplasia. Risk of progressi...
Establishing a Primary Care Alliance for Conducting Cancer Prevention Clinical Research at Community Sites
Establishing a Primary Care Alliance for Conducting Cancer Prevention Clinical Research at Community Sites
AbstractIn September 2020, the National Cancer Institute convened the first PARTNRS Workshop as an initiative to forge par...
Bilateral Salpingo-oophorectomy and Breast Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Assessing the Evidence
Bilateral Salpingo-oophorectomy and Breast Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Assessing the Evidence
Historical studiesA meta-analysis by Rebbeck and colleagues (3), published in 2009, evaluated four case–control or cohort ...
Editors' Selections from Relevant Scientific Publications
Editors' Selections from Relevant Scientific Publications
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