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The Value of Serum Nestin in Monitoring the Effects of Surgery and Chemotherapy in Female Breast Cancer Patients: A Comparison with Serum CA15.3
Background: Traditional tumor markers such as cancer antigen 15.3 (CA15.3) and carcinoembryonic antigen (CEA) exhibit limi...
Molecular Characterization and Metastatic Gene Signatures Based on Targeted Cancer Treatment Modalities
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Evaluation of the Interchangeability of Cone Beam Computed Tomography and Catalyst for Patient Positioning in Radiotherapy for Head and Neck Cancer Patients
Background: This study aims to evaluate the interchangeability between cone beam computed tomography (CBCT) and the optica...
An Ensemble Deep Learning Model for the Detection and Classification of Breast Cancer
Background: Detecting breast cancer in its early stages remains a significant challenge in the present context and is a le...
Disseminated Metastasis after Resection of Sacrococcygeal Teratoma with Mucinous Adenocarcinoma: A Case Report
Mature teratoma is a common tumor that can undergo malignant transformation, either in ovarian or extragonadal sites. Whil...
Primary Extraskeletal Ewing Sarcoma of the Pancreas - A Case Report
Extraskeletal Ewing sarcomas (EES) is a rare, aggressive malignancy that typically affects adolescents or young adults, pr...
Sipple Syndrome: From Diagnosis to Management - A Case Report
Multiple endocrine neoplasia (MEN) is a rare inherited disease caused by multiple complex mutations in the RET gene. It is...
Prognostic Significance of Notch-4, SATB-2, and Glutaminase-1 in Colorectal Adenocarcinoma
Background: Neurogenic Locus Notch Homology 4 (Notch-4) is crucial in maintaining stem cells. Special AT-rich sequence-bin...
Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients
Background: This study aimed to evaluate serum vitamin D levels in patients with oral lichen planus (OLP) and oral squamou...
Evaluation of Fis-1 and miR-484 Expression Levels in Tumor Tissue Samples and Healthy Tumor Margins in Lung Cancer
Background: MicroRNAs (miRNAs) regulate gene expression and various cellular activities. They also hold significant import...
MYCN Gene Copy Number Status Detected by FISH Method and Its Correlation with Outcome and Clinicopathological Variables in Childhood Neuroblastoma
Background: Neuroblastoma is the most common extracranial solid tumor in children. MYCN gene amplification (MNA) is an ind...
Improvement of NK Cell Cytotoxicity in Reconstituting NK Cells after Allogeneic Stem Cell Transplantation by Blocking NKG2A Checkpoint
Background: One cause of tumor relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the alterat...
Cancer Screening: Knowledge, Attitudes, and Practices among Healthcare Personnel
Background: It is crucial for medical personnel to be aware of cancer symptoms and engage in appropriate screening practic...
Feasibility of Dose Reduction to the Left Anterior Descending Coronary Artery without Compromising Target Volume Coverage Using Tomotherapy Techniques
Background: Radiotherapy is associated with a high risk of heart disease in patients with left-sided breast cancer. Previo...
The Dosimetric Performance of Volumetric Modulated Arc Therapy and Intensity Modulated Radiation Therapy in the Treatment of Locally Advanced Laryngeal Cancer
Background: This study aims to compare the performance of intensity modulated radiation therapy (IMRT) and volumetric modu...
Evaluation of TRAF3IP2 Gene Expression in Brain Tumor Tissue of Patients with Glioblastoma Multiforme in Comparison to Non-Tumoral Brain Tissue
Background: Glioblastoma, not otherwise specified (NOS), is the most common primary malignant brain tumor. The TRAF3IP2 ge...
Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions
Background: Preoperative marking of impalpable breast lesions is crucial for limiting false negative results and reducing ...
The Effect of Bortezomib Regimen on Multiple Myeloma Patients Infected with COVID-19
Background: Patients with multiple myeloma (MM) have compromised immune systems due to the nature of the malignancy and an...
Second-line Modified GTX versus Gemcitabine-Nab-Paclitaxel (GmAb) Following First-Line FOLFIRINOX in Advanced Pancreatic Cancer: A Retrospective Analysis at the American University of Beirut Medical Center (AUBMC)
Background: Pancreatic cancer is characterized by its generally poor prognosis and ranks seventh worldwide in cancer-relat...
Identification of Immunogenic Proteins in Early and Advanced Stages of Breast Cancer: An Immunoproteomics Study
Background: Early detection of breast cancer (BC) is extremely important as late diagnosis has been associated with a high...
Prostate Cancer Survival Analysis of 872 Patients in Southern Iran: A Retrospective Cohort Study
Background: Prostate cancer remains one of the most common and lethal cancers among men worldwide. This study aimed to inv...
Vitamin D Serum Level in Oral Lichen Planus and Oral Cancer Patients
Background: This study aimed to evaluate serum vitamin D levels in patients with oral lichen planus (OLP) and oral squamou...
Comparison of Carcinoembryonic Antigen Level and E-Cadherin Expression between Metastatic and Non-Metastatic Colorectal Carcinoma in RSUP, Dr. Sardjito Yogyakarta-Indonesia
Background: WHO has reported 34,189 (8.6%) colorectal carcinoma cases out of 396,914 total cancer cases in Indonesia. Accu...
Evaluation of the Serum Levels of TNF-α and Interleukin-6 as Potential Diagnostic Biomarkers in the First-Degree Relatives of Patients with Gastric Cancer: A Case-Control Study
Background: Gastric cancer is one of the most prevalent ones with high incidence and mortality worldwide. The aim of this ...
The Effect of Vincristine on Hypoxic, Apoptotic, and Autophagic Gene Expressions in Gastric Cancer Cells under Hypoxic Conditions
Background: Apoptosis and autophagy functions are known as death-inducing mechanisms. Vincristine (VCR) is a chemotherapeu...
Evaluating Oxidative Stress Condition in Human Bladder Cancer 5637 Cell Line upon Exposure to Silver Nanoparticles
Background: Bladder cancer (BC) is known as the most frequent neoplasm of the urinary system, whose prevalence has signifi...
The Emerging Role of Chitosan-based Polymeric Nanoparticles in the Diagnosis and Treatment of Gynecological Cancers
Breast and gynecological cancers are the most common malignancies in females. Early-stage detection and treatment could si...
The Protective Effect of Curcumin on Hepatic Function in Cancer Patients Receiving Taxane-Based Chemotherapy: A Randomized Controlled Clinical Trial
Background: Cancer has become a significant health challenge in recent decades. The Taxane family is one of the popular ch...
Anticancer Effect of Carob Bean Extract on Human Prostate Cancer Cell Lines: Apoptosis Induction and Bax/Bcl-2 Ratio Improvement
Background: Carob (Ceratonia siliqua L.) has been used to cure various diseases in traditional medicine. This plant has al...
The Impact of Radiotherapy Boost Dose Delivery in Breast Cancer Treatment on Acute Skin Reactions and Cosmetic Outcome: A Randomized Trial of Sequential and Concomitant Schedules Boost
Background: Minimizing the overall treatment time is an issue of great importance in cancer management. Concomitant boost ...
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