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Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions
Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions
Pterostilbene (PT), a natural dimethoxy analogue of resveratrol, exhibits enhanced bioavailability and lipophilicity, maki...
Radiomics applications in the modern management of esophageal squamous cell carcinoma
Radiomics applications in the modern management of esophageal squamous cell carcinoma
Esophageal cancer ranks among the most lethal malignancies globally, with China accounting for more than half of worldwide...
Toward diffusion MRI in the diagnosis and treatment of pancreatic cancer
Toward diffusion MRI in the diagnosis and treatment of pancreatic cancer
Pancreatic cancer is a highly aggressive malignancy with rising incidence and mortality rates, often diagnosed at advanced...
Cx43 mediates cross-talk of tumor cells and macrophage via cGAS-STING signaling
Cx43 mediates cross-talk of tumor cells and macrophage via cGAS-STING signaling
Tumor microenvironment (TME) plays a pivotal role in immunotherapy, especially in immune checkpoint inhibitors (ICIs) ther...
Demographic and prognostic factors affecting survival in invasive mucinous adenocarcinoma: a national cancer database analysis
Demographic and prognostic factors affecting survival in invasive mucinous adenocarcinoma: a national cancer database analysis
Invasive mucinous adenocarcinoma (IMA) is a rare lung tumor with a distinctive histology of goblet and columnar cells char...
Correction to: Downregulation of suppressed migration and invasion by regulating epithelial–mesenchymal transition in prostate cancer cells
Correction to: Downregulation of suppressed migration and invasion by regulating epithelial–mesenchymal transition in prostate cancer cells
Cite this articleChen, L., Cao, R., Wang, G. et al. Correction to: Downregulation of TRPM7 suppressed migration and invasi...
Differential regulation of STING expression and cisplatin sensitivity by autophagy in non-small cell lung cancer cells
Differential regulation of STING expression and cisplatin sensitivity by autophagy in non-small cell lung cancer cells
The cGAS-STING pathway is a central signalling mechanism in inflammatory responses and can be activated by cisplatin. Incr...
Investigating the antiproliferative mechanisms of NaHS, a hydrogen sulfide donor, in the SH-SY5Y cell line
Investigating the antiproliferative mechanisms of NaHS, a hydrogen sulfide donor, in the SH-SY5Y cell line
Neuroblastoma, a childhood cancer, arises from neural crest cells within the sympathetic nervous system. This study invest...
Revolutionising cancer intervention: the repercussions of CAR-T cell therapy on modern oncology practices
Revolutionising cancer intervention: the repercussions of CAR-T cell therapy on modern oncology practices
Chimeric Antigen Receptor T-cell (CAR-T) therapy represents a groundbreaking advance in oncology, leveraging patient-speci...
Synthesis, characterization, and evaluation of the cytotoxic effects of caffeine nanoparticles on K562 cancer cell line
Synthesis, characterization, and evaluation of the cytotoxic effects of caffeine nanoparticles on K562 cancer cell line
Caffeine (1, 3, 7—trimethylxanthine) can be used as an anti-cancer compound in low concentrations. Considering this ...
SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
Recently, we reported that the SARS-CoV-2 nucleocapsid (N) protein triggers DNA damage by inducing autophagic degradation ...
Targeting endothelial growth factor receptor in thyroid cancer: current concepts and future directions
Targeting endothelial growth factor receptor in thyroid cancer: current concepts and future directions
Thyroid cancer (TC) ranks among the most prevalent cancers globally. The incidence rate of thyroid cancer has significantl...
Bit1 promotes the progression of gastric cancer by facilitating epithelial–mesenchymal transition and alleviating apoptosis
Bit1 promotes the progression of gastric cancer by facilitating epithelial–mesenchymal transition and alleviating apoptosis
Gastric cancer remains the fifth most common malignant cancer all around the world, in 2024, 2,001,140 new cancer cases an...
Targeting platelet-tumor cell interactions: a novel approach to cancer therapy
Targeting platelet-tumor cell interactions: a novel approach to cancer therapy
Metastasis—the dissemination of cancer cells to distant organs—is the leading cause of cancer-related death. B...
Antitumor effect of BC12-3 on multiple myeloma via proteasome inhibition
Antitumor effect of BC12-3 on multiple myeloma via proteasome inhibition
Multiple myeloma (MM) ranks second only to lymphoma among hematologic malignancies in terms of incidence. Current treatmen...
Genetic, epigenetic, and molecular determinants of multiple myeloma and precursor plasma cell disorders: a pathophysiological overview
Genetic, epigenetic, and molecular determinants of multiple myeloma and precursor plasma cell disorders: a pathophysiological overview
Multiple myeloma (MM) is a malignancy of clonal plasma cells that arises from precursor conditions, including monoclonal g...
Targeting Gastrointestinal Cancers with Cannabidiol: Mechanisms, Challenges, and Therapeutic Implications
Targeting Gastrointestinal Cancers with Cannabidiol: Mechanisms, Challenges, and Therapeutic Implications
Cannabidiol (CBD), a non-psychoactive compound derived from cannabis, has gained significant attention for its potential t...
Integration of immunotherapy and radiotherapy in a therapeutic algorithm for locally advanced squamous cell skin cancer
Integration of immunotherapy and radiotherapy in a therapeutic algorithm for locally advanced squamous cell skin cancer
Locally advanced squamous cell skin cancer (LA-sqCSC) affects older patients who initially decline medical assistance and ...
Advancing the potential of nanoparticles for cancer detection and precision therapeutics
Advancing the potential of nanoparticles for cancer detection and precision therapeutics
Cancer poses a significant challenge with high death rate marked by heterogeneity, complexity, and resistance to available...
Introducing the ELPIS scale: a novel tool for measuring emotional empathy toward cancer patients
Introducing the ELPIS scale: a novel tool for measuring emotional empathy toward cancer patients
Empathy, defined as the ability to understand and share another person’s feelings, is crucial in the healthcare sett...
siRNA-based strategies to combat drug resistance in gastric cancer
siRNA-based strategies to combat drug resistance in gastric cancer
Chemotherapy is a key treatment option for gastric cancer, but over 50% of patients develop either inherent or acquired re...
Transforming cancer detection and treatment with nanoflowers
Transforming cancer detection and treatment with nanoflowers
Nanoflowers, an innovative class of nanoparticles with a distinctive flower-like structure, have garnered significant inte...
Effectiveness of complete decongestive therapy for upper extremity breast cancer-related lymphedema: a review of systematic reviews
Effectiveness of complete decongestive therapy for upper extremity breast cancer-related lymphedema: a review of systematic reviews
Breast cancer-related lymphedema (BCRL) remains a challenging condition impacting function and quality of life. Complete d...
Post-operative care for patients following surgical treatment of lymphedema
Post-operative care for patients following surgical treatment of lymphedema
Surgical treatments are promising for the treatment of lymphedema. It is important for patients, healthcare providers, and...
Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel
Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel
Several recent studies have investigated the validity of precautionary practices for lymphedema risk reduction after breas...
Self-assembled nanoparticles of alginate and paclitaxel-triphenylphosphonium for mitochondrial apoptosis targeting
Self-assembled nanoparticles of alginate and paclitaxel-triphenylphosphonium for mitochondrial apoptosis targeting
Paclitaxel (PTX), an antimitotic drug from the taxanes group, prevents the proliferation of breast cancer cells through mi...
Understanding the chemistry & pharmacology of antibody–drug conjugates in triple-negative breast cancer with special reference to exatecan derivatives
Understanding the chemistry & pharmacology of antibody–drug conjugates in triple-negative breast cancer with special reference to exatecan derivatives
In the spectrum of breast malignancies, triple-negative breast cancer is the most widely spreading subtype of breast cance...
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a leading liver cancer that significantly impacts global life expectancy and remains cha...
Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery
Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery
Glioblastoma (GBM) is a highly prevalent and aggressive brain tumor in adults with limited treatment response, leading to ...
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer
As the first anti-HER2 targeted agent approved by FDA in 1998, Trastuzumab has significantly improved the outcome of patie...
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