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Prognostic Significance of Circulating Tumor DNA Mutations in Gastrointestinal Stromal Tumors: A Systematic Review and Meta-analysis Based on Time-To-Event Data
Prognostic Significance of Circulating Tumor DNA Mutations in Gastrointestinal Stromal Tumors: A Systematic Review and Meta-analysis Based on Time-To-Event Data
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the digestive tract, most commonly originating i...
Robotic Versus Laparoscopic Lateral Lymph Node Dissection for Advanced Pelvic Cancers: a Systematic Review and Meta-analysis
Robotic Versus Laparoscopic Lateral Lymph Node Dissection for Advanced Pelvic Cancers: a Systematic Review and Meta-analysis
Lateral pelvic lymph node dissection (LPND) is a key component in the surgical treatment of advanced pelvic malignancies. ...
A Prospective Observational Study on Compliance with Enhanced Recovery Pathways and Their Impact on Postoperative Outcomes Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
A Prospective Observational Study on Compliance with Enhanced Recovery Pathways and Their Impact on Postoperative Outcomes Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Enhanced recovery pathways have been shown to improve postoperative morbidity and reduce hospital stay across various surg...
Frequency of Chronic Liver Disease Due to Chemotherapy-Associated Liver Injury in Patients with Gastrointestinal Cancers
Frequency of Chronic Liver Disease Due to Chemotherapy-Associated Liver Injury in Patients with Gastrointestinal Cancers
Chronic liver disease (CLD) has been reported in long-term survivors of gastrointestinal (GI) cancers treated with irinote...
Imaging Characteristics and Clinical Outcomes in Gastric Cancer with Brain Metastasis: A Propensity Score-Matched Study
Imaging Characteristics and Clinical Outcomes in Gastric Cancer with Brain Metastasis: A Propensity Score-Matched Study
This study aimed to investigate the impact of brain metastasis (BM) on the clinical outcomes of gastric cancer (GC) and ex...
Prostate-Specific Membrane Antigen Expression in Colorectal Cancer and Its Potential Implication in Disease Monitoring in Rectal Cancer
Prostate-Specific Membrane Antigen Expression in Colorectal Cancer and Its Potential Implication in Disease Monitoring in Rectal Cancer
Prostate-specific membrane antigen (PSMA) is expressed in tumor-associated vessels of diverse malignancies, such as colore...
Outcomes of Conversion Surgery vs Conventional Systemic Therapy in Stage IV Gastric Cancer: A Systematic Review and Meta-Analysis
Outcomes of Conversion Surgery vs Conventional Systemic Therapy in Stage IV Gastric Cancer: A Systematic Review and Meta-Analysis
The overall prognosis of stage IV gastric cancer (GC) is poor. Large-scale and high-quality evidence on the role of conver...
Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
Portal vein tumor thrombus (PVTT) develops in up to half of patients with hepatocellular carcinoma (HCC) and historically ...
“Impact of Limberg Flap Reconstruction Following Abdominoperineal Resection: A Randomized Controlled Trial.”
“Impact of Limberg Flap Reconstruction Following Abdominoperineal Resection: A Randomized Controlled Trial.”
Perineal wound complications after abdominoperineal resection (APR) for low rectal cancer remain a significant challenge. ...
Comprehensive Analysis of Native Hawaiians and Other Pacific Islanders with Early Onset Colorectal Cancer
Comprehensive Analysis of Native Hawaiians and Other Pacific Islanders with Early Onset Colorectal Cancer
Rates of early-onset colorectal cancers (EOCRC) are increasing in Hawaii across all racial groups. Previous studies have s...
Screening Uptake and Diagnostic Yield of One-time Fecal Immunochemical Testing Vs One-time Colonoscopy for Colorectal Cancer: a Systematic Review and Meta-analysis
Screening Uptake and Diagnostic Yield of One-time Fecal Immunochemical Testing Vs One-time Colonoscopy for Colorectal Cancer: a Systematic Review and Meta-analysis
Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide. In recent ye...
Survival Benefits of Neoadjuvant Immunochemotherapy Versus Chemotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma: A Propensity Matched Score
Survival Benefits of Neoadjuvant Immunochemotherapy Versus Chemotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma: A Propensity Matched Score
While neoadjuvant chemotherapy (NCT) and neoadjuvant immunochemotherapy (NICT) are effective treatments for locally advanc...
Trends and Disparities in Mortality Due to Gastric Malignancies the United States: A Nationwide Analysis from 1999 to 2020
Trends and Disparities in Mortality Due to Gastric Malignancies the United States: A Nationwide Analysis from 1999 to 2020
Gastric malignancies remain a significant public health concern and a major contributor to cancer-related mortality worldw...
Systematic Analysis of the Differential Effects of Red Meat on Colorectal Cancer Risks: A Meta-Analytic Approach
Systematic Analysis of the Differential Effects of Red Meat on Colorectal Cancer Risks: A Meta-Analytic Approach
Colorectal cancer (CRC) is the third most common cancer worldwide, with rising incidence in younger populations. Red meat ...
Effects of Sarcopenia on Patient Outcomes in Gastrointestinal Cancer: An Umbrella Review of Published Meta-Analyses
Effects of Sarcopenia on Patient Outcomes in Gastrointestinal Cancer: An Umbrella Review of Published Meta-Analyses
Gastrointestinal tumors represent a significant proportion of malignant neoplasms worldwide. Sarcopenia has emerged as a c...
Efficacy and Safety of Metronomic Capecitabine in Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Efficacy and Safety of Metronomic Capecitabine in Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Metronomic capecitabine has been found to be useful in several types of cancers such as pancreatic cancer, breast cancer, ...
Role of Interleukins in Pancreatic Cancer: A Literature Review
Role of Interleukins in Pancreatic Cancer: A Literature Review
This review article summarizes the pathophysiological aspects of interleukins (ILs) including IL-1, IL-2, IL-3, IL-4, IL-5...
Endoscopic Resection of Stage T1 Colorectal Adenocarcinoma Followed by Surgical Intervention: a Single-center Retrospective Study
Endoscopic Resection of Stage T1 Colorectal Adenocarcinoma Followed by Surgical Intervention: a Single-center Retrospective Study
Domestic and international guidelines recommend endoscopic resection for stage T1 colorectal adenocarcinoma with indicatio...
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Fruquintinib has received approval for the management of patients with chemotherapy-resistant metastatic colorectal cancer...
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary intrahepatic mesothelioma (PIHMM) has been rarely reported. Its typical clinical presentation, radiological featur...
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal leiomyosarcoma (CR-LMS) is a rare neoplasm arising from smooth muscle cells. It accounts for less than 0.1% of ...
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Hepatocellular carcinoma (HCC) is the most common primary carcinoma arising from the liver. Although HCC can arise de novo...
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Intrahepatic cholangiocarcinoma is a biliary neoplasm usually showing a dismal prognosis. In early stages, surgical resect...
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
The clinical effectiveness of triple chemotherapy consisting of gemcitabine, cisplatin plus either S-1 (GCS), durvalumab (...
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
As long-term survival improves after allogeneic hematopoietic stem cell transplantation (HSCT), the risk for secondary sol...
Anti-EGFR Rechallenge in Metastatic Colorectal Cancer and the Role of ctDNA: A Systematic Review and Meta-analysis
Anti-EGFR Rechallenge in Metastatic Colorectal Cancer and the Role of ctDNA: A Systematic Review and Meta-analysis
Metastatic colorectal cancer (mCRC) remains a significant clinical challenge. While anti-EGFR inhibitors have improved sur...
A Phase 2 study of Savolitinib in Patients with MET Amplified Metastatic Colorectal Cancer
A Phase 2 study of Savolitinib in Patients with MET Amplified Metastatic Colorectal Cancer
MET amplification (amp) is a driver of acquired resistance to epidermal growth factor receptor (EGFR) antibodies in patien...
Delayed Surgery after Neoadjuvant Short-course Radiation for Rectal Cancer Improves Pathologic Outcomes without Impacting Survival: A National Cancer Database Analysis
Delayed Surgery after Neoadjuvant Short-course Radiation for Rectal Cancer Improves Pathologic Outcomes without Impacting Survival: A National Cancer Database Analysis
Interval to surgery following short course radiotherapy (SCRT) for rectal cancer is not standardized. This study investiga...
The Association Between Patient-Reported Outcomes and Surgical Attrition During Neoadjuvant Therapy for Gastrointestinal Malignancies
The Association Between Patient-Reported Outcomes and Surgical Attrition During Neoadjuvant Therapy for Gastrointestinal Malignancies
Neoadjuvant therapy (NT) is increasingly used for gastrointestinal (GI) and hepatopancreatobiliary (HPB) cancers. Risk fac...
Predictors of Understaging with EUS and PET-CECT in Early Esophageal Carcinoma
Predictors of Understaging with EUS and PET-CECT in Early Esophageal Carcinoma
The clinicoradiological staging for esophageal cancer is fraught with variable accuracy, potentially depriving patients wh...
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