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Predictors of brain metastases in patients with oligometastatic solid tumours treated with stereotactic body radiation therapy
Predictors of brain metastases in patients with oligometastatic solid tumours treated with stereotactic body radiation therapy
In patients with oligometastatic disease (OMD) treated with stereotactic body radiation therapy (SBRT), those who develop ...
Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium
Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium
Spine metastases are a major burden of oncologic care, contributing to substantial morbidity. A well-established treatment...
How well can simple clinical features predict long-term language recovery after left-hemisphere glioma surgery?
How well can simple clinical features predict long-term language recovery after left-hemisphere glioma surgery?
Long-term language recovery after left-hemisphere glioma surgery varies substantially across patients. We investigated how...
The 4S of spinal astrocytoma: specific location, syrinx, spasticity and score on Modified Mccormick Scale (MMS) predict long term outcomes in patients undergoing surgical resection of intramedullary spinal astrocytomas
The 4S of spinal astrocytoma: specific location, syrinx, spasticity and score on Modified Mccormick Scale (MMS) predict long term outcomes in patients undergoing surgical resection of intramedullary spinal astrocytomas
The aim of this study was to explore the factors that could predict long term clinical outcomes in SA. A retrospective stu...
Clinical trial design for novel targeted agents in neuro-oncology
Clinical trial design for novel targeted agents in neuro-oncology
Biomarker-based clinical trials investigating targeted treatments for brain tumors have surged due to better access to bio...
Association of preoperative seizures with reduced expression of soluble CD163, an M2 macrophage marker, in the cerebrospinal fluid in isocitrate dehydrogenase wild-type glioblastoma
Association of preoperative seizures with reduced expression of soluble CD163, an M2 macrophage marker, in the cerebrospinal fluid in isocitrate dehydrogenase wild-type glioblastoma
To investigate the relationship between the tumor microenvironment (TME), tumor-related seizures (TRS), and cerebrospinal ...
Impact of upfront adjuvant chemoradiation on survival in patients with molecularly defined oligodendroglioma: the benefits of PCV over TMZ
Impact of upfront adjuvant chemoradiation on survival in patients with molecularly defined oligodendroglioma: the benefits of PCV over TMZ
Oligodendroglioma is an adult-type diffuse glioma defined by 1p/19q codeletion and IDH1/2 mutation. Treatment includes sur...
In-patient neurosurgical tumor treatments for malignant glioma patients in Germany
In-patient neurosurgical tumor treatments for malignant glioma patients in Germany
Treatment for malignant gliomas involves multiple disciplines, including neurosurgery, radiation therapy, medical and neur...
Advanced imaging reveals enhanced malignancy in glioblastomas involving the subventricular zone: evidence of increased infiltrative growth and perfusion
Advanced imaging reveals enhanced malignancy in glioblastomas involving the subventricular zone: evidence of increased infiltrative growth and perfusion
Glioblastoma’s infiltrative growth and heterogeneity are influenced by neural, molecular, genetic, and immunological...
Development and application of explainable artificial intelligence using machine learning classification for long-term facial nerve function after vestibular schwannoma surgery
Development and application of explainable artificial intelligence using machine learning classification for long-term facial nerve function after vestibular schwannoma surgery
Vestibular schwannomas (VSs) represent the most common cerebellopontine angle tumors, posing a challenge in preserving fac...
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2–3 gliomas
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2–3 gliomas
Radiation therapy (RT) is an integral treatment component in patients with glioma but associated with neurotoxicity. Proto...
Congress of Neurological Surgeons systematic review and evidence‑based guidelines on the management of recurrent diffuse low-grade glioma: update
Congress of Neurological Surgeons systematic review and evidence‑based guidelines on the management of recurrent diffuse low-grade glioma: update
Target population These recommendations apply to adult patients with recurrent WHO grade 2 infiltrative diffuse glioma (ol...
Social media “SoMe” in neuro-oncology: a review of the literature
Social media “SoMe” in neuro-oncology: a review of the literature
This article examines the current state of social media (SoMe) in neuro-oncology and neurosurgical oncology. The goal of t...
DTI fiber-tracking parameters adjacent to gliomas: the role of tract irregularity value in operative planning, resection, and outcome
DTI fiber-tracking parameters adjacent to gliomas: the role of tract irregularity value in operative planning, resection, and outcome
The goal of glioma surgery is maximal tumor resection associated with minimal post-operative morbidity. Diffusion tensor i...
Therapeutic strategies for mobile spine chordoma: en bloc Versus intralesional surgery with adjuvant charged-particle therapy
Therapeutic strategies for mobile spine chordoma: en bloc Versus intralesional surgery with adjuvant charged-particle therapy
The aim of this retrospective study is to analyze the impact of en bloc resection with negative margins versus intralesion...
Intrathecal anti-PD-1 treatment in metastatic melanoma patients with leptomeningeal disease (LMD): real-world data and evidence
Intrathecal anti-PD-1 treatment in metastatic melanoma patients with leptomeningeal disease (LMD): real-world data and evidence
Leptomeningeal disease (LMD) is a severe complication of melanoma with a very poor prognosis. Despite improved treatment s...
Early experience with an artificial intelligence-based module for brain metastasis detection and segmentation
Early experience with an artificial intelligence-based module for brain metastasis detection and segmentation
– Accurate detection, segmentation, and volumetric analysis of brain lesions are essential in neuro-oncology. Artifi...
Pre-treatment systemic inflammation response index and systemic immune inflammation in patients with primary central nerve system lymphoma as a useful prognostic indicator
Pre-treatment systemic inflammation response index and systemic immune inflammation in patients with primary central nerve system lymphoma as a useful prognostic indicator
The systemic inflammation response index (SIRI) and systemic immune-inflammation index (SII) are based on neutrophil, mono...
Constitutive type-1 interferons signaling activity in malignant gliomas
Constitutive type-1 interferons signaling activity in malignant gliomas
Recent studies revealed a pro-tumor effect of constitutive Type-1 interferons (IFN-I) production and the downstream signal...
Frailty in patients with IDH-mutant gliomas: experience from a high-volume tumor center
Frailty in patients with IDH-mutant gliomas: experience from a high-volume tumor center
Gliomas are increasingly diagnosed in an aging population, with treatment outcomes influenced by factors like tumor geneti...
Long term follow-up of patients with newly diagnosed glioblastoma treated by intraoperative photodynamic therapy: an update from the INDYGO trial (NCT03048240)
Long term follow-up of patients with newly diagnosed glioblastoma treated by intraoperative photodynamic therapy: an update from the INDYGO trial (NCT03048240)
Glioblastoma remains incurable despite optimal multimodal management. The interim analysis of open label, single arm INDYG...
Histopathological correlation of brain tumor recurrence vs. radiation effect post-radiosurgery as detected by MRI contrast clearance analysis: a validation study
Histopathological correlation of brain tumor recurrence vs. radiation effect post-radiosurgery as detected by MRI contrast clearance analysis: a validation study
The differentiation between adverse radiation effects (ARE) and tumor recurrence or progression (TRP) is a major decision-...
Neuroradiological features of patients with bilateral macronodular adrenocortical disease and meningiomas associated or not with genetic variants of ARMC5– a case series
Neuroradiological features of patients with bilateral macronodular adrenocortical disease and meningiomas associated or not with genetic variants of ARMC5– a case series
Meningiomas are the most common primary brain and central nervous system tumors, accounting for approximately 40% of these...
Intraoperative radiotherapy combined with spinal stabilization surgery—a novel treatment strategy for spinal metastases based on a first single-center experiences
Intraoperative radiotherapy combined with spinal stabilization surgery—a novel treatment strategy for spinal metastases based on a first single-center experiences
Current treatment of spinal metastases (SM) aims on preserving spinal stability, neurological status, and functional statu...
Personalized prognosis stratification of newly diagnosed glioblastoma applying a statistical decision tree model
Personalized prognosis stratification of newly diagnosed glioblastoma applying a statistical decision tree model
Glioblastoma (GBM) is the most frequent glioma in adults with a high treatment resistance resulting into limited survival....
Screening and surveillance recommendations for central nervous system hemangioblastomas in pediatric patients with Von Hippel-Lindau disease
Screening and surveillance recommendations for central nervous system hemangioblastomas in pediatric patients with Von Hippel-Lindau disease
Von Hippel-Lindau (VHL) disease is an autosomal-dominantly inherited tumor predisposition syndrome. One of the most common...
Treatment, healthcare utilization and outcomes in patients with glioblastoma in Ontario: a 10-year cohort study
Treatment, healthcare utilization and outcomes in patients with glioblastoma in Ontario: a 10-year cohort study
Glioblastoma (GBM) is the most common malignant primary brain tumour in adults. Receipt of adjuvant therapies has been sho...
Impact of concurrent antibody–drug conjugates and radiotherapy on symptomatic radiation necrosis in breast cancer patients with brain metastases: a multicenter retrospective study
Impact of concurrent antibody–drug conjugates and radiotherapy on symptomatic radiation necrosis in breast cancer patients with brain metastases: a multicenter retrospective study
We aimed to investigate the impact of concurrent antibody–drug conjugates (ADC) and radiotherapy on symptomatic radi...
Pharmaceutical equivalent 5-aminolevulinic acid fluorescence guided resection of central nervous system tumors: feasibility, safeness and cost-benefit considerations
Pharmaceutical equivalent 5-aminolevulinic acid fluorescence guided resection of central nervous system tumors: feasibility, safeness and cost-benefit considerations
5-aminolevulinic acid (5-ALA) fluorescence-guided resection (FGR) has been an essential tool in the ‘standard of car...
Use of complementary therapies and supportive measures of patients with intracranial gliomas—a prospective evaluation in an outpatient clinic
Use of complementary therapies and supportive measures of patients with intracranial gliomas—a prospective evaluation in an outpatient clinic
Patients with intracranial gliomas frequently seek for complementary and alternative medicine (CAM), in addition to guidel...
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