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Large vestibular schwannoma treated using a cranial nerve sparing approach with planned subtotal microsurgical resection and stereotactic radiosurgery: meta-analysis and International Stereotactic Radiosurgery Society (ISRS) practice guidelines
Large vestibular schwannoma treated using a cranial nerve sparing approach with planned subtotal microsurgical resection and stereotactic radiosurgery: meta-analysis and International Stereotactic Radiosurgery Society (ISRS) practice guidelines
Stereotactic radiosurgery (SRS) has become a standard of care for small- to medium- size vestibular schwannomas (VS), whil...
Outcomes of concurrent versus non-concurrent immune checkpoint inhibition with stereotactic radiosurgery for melanoma brain metastases
Outcomes of concurrent versus non-concurrent immune checkpoint inhibition with stereotactic radiosurgery for melanoma brain metastases
Immune checkpoint inhibition (ICI) has revolutionized the treatment of melanoma care. Stereotactic radiosurgery combined w...
The association of neighborhood-level deprivation with glioblastoma outcomes: a single center cohort study
The association of neighborhood-level deprivation with glioblastoma outcomes: a single center cohort study
Glioblastoma is the most common primary brain malignancy. Though literature has suggested the association of glioblastoma ...
Repeat stereotactic radiosurgery for recurrent brain metastases: a retrospective comparison of local progression and distant brain metastases after prior radiosurgery
Repeat stereotactic radiosurgery for recurrent brain metastases: a retrospective comparison of local progression and distant brain metastases after prior radiosurgery
This study evaluated the efficacy and safety of repeat stereotactic radiosurgery (SRS) for recurrent brain metastases (BMs...
Patterns of response following gamma knife radiosurgery for tectal plate gliomas
Patterns of response following gamma knife radiosurgery for tectal plate gliomas
Tectal plate gliomas are slow-growing brainstem tumors often causing obstructive hydrocephalus. This study evaluates radio...
Prognostic implications of DNA methylation machinery (DNMTs and TETs) expression in gliomas: correlations with tumor grading and patient survival
Prognostic implications of DNA methylation machinery (DNMTs and TETs) expression in gliomas: correlations with tumor grading and patient survival
DNA methylation is a crucial epigenetic modification that regulates gene expression and chromatin structure. Its dysregula...
Use of psychotropic medications among glioma patients in Denmark, Norway, Sweden, and Wales
Use of psychotropic medications among glioma patients in Denmark, Norway, Sweden, and Wales
Glioma patients often suffer from psychiatric and neurological conditions. However, little is known about the patterns of ...
Epidemiology and palliative care of in-patient cerebral metastases cases in Germany
Epidemiology and palliative care of in-patient cerebral metastases cases in Germany
Cerebral metastases (CM) are the most common intracranial neoplasms, significantly impacting patient quality-of-life. Desp...
Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response
Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response
Recurrent glioblastomas showing a survival benefit from anti-VEGF agents are known to exhibit a distinct diffusion MRI phe...
Stereotactic body radiation therapy for spinal metastases from gastrointestinal primary cancers
Stereotactic body radiation therapy for spinal metastases from gastrointestinal primary cancers
Metastases from gastrointestinal (GI) primary cancers are considered relatively radioresistant. This study is one of the l...
Pitfalls in the evaluation of copy number status in meningioma
Pitfalls in the evaluation of copy number status in meningioma
Meningiomas are the most common primary intracranial tumors, with anaplastic variants linked to a poor prognosis. CDKN2A d...
Glioma-derived SPARCL1 promotes the formation of peritumoral neuron–glioma synapses
Glioma-derived SPARCL1 promotes the formation of peritumoral neuron–glioma synapses
Gliomas are the most common type of primary malignant brain tumor with high degree of malignancy and rapid progression, an...
Variables associated with 90-day readmission following craniotomy for tumor in the pediatric population
Variables associated with 90-day readmission following craniotomy for tumor in the pediatric population
Readmission is a vital component of healthcare quality and is one of the core group metrics for quality-dependent outcomes...
Acute side effects of proton and photon radiotherapy for medulloblastoma: a retrospective national multicenter study
Acute side effects of proton and photon radiotherapy for medulloblastoma: a retrospective national multicenter study
A comparison of acute toxicity between photon and proton radiotherapy (RT) for children undergoing treatment for medullobl...
Impact of brain metastasis size at the time of radiotherapy on local control and radiation necrosis
Impact of brain metastasis size at the time of radiotherapy on local control and radiation necrosis
No consensus has been reached regarding whether upfront versus deferred radiation to small, asymptomatic brain metastases ...
Individualized therapeutic approaches for relapsed and refractory pediatric ependymomas: a single institution experience
Individualized therapeutic approaches for relapsed and refractory pediatric ependymomas: a single institution experience
This retrospective study aims to show a real-life single-center experience with clinical management of relapsed pediatric ...
A Delphi study of current practices and establishing consensus regarding assessment of fitness to drive among patients with brain tumours
A Delphi study of current practices and establishing consensus regarding assessment of fitness to drive among patients with brain tumours
Evaluating fitness to drive among patients with brain tumours remains a challenge for clinicians. Due to difficulties in c...
Increased cortical iron deposition in glioma patients: a quantitative susceptibility mapping study
Increased cortical iron deposition in glioma patients: a quantitative susceptibility mapping study
This study aimed to evaluate how cortical gray matter iron, measured using quantitative susceptibility mapping (QSM), chan...
Predictors of brain metastases in patients with oligometastatic solid tumours treated with stereotactic body radiation therapy
Predictors of brain metastases in patients with oligometastatic solid tumours treated with stereotactic body radiation therapy
In patients with oligometastatic disease (OMD) treated with stereotactic body radiation therapy (SBRT), those who develop ...
Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium
Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium
Spine metastases are a major burden of oncologic care, contributing to substantial morbidity. A well-established treatment...
How well can simple clinical features predict long-term language recovery after left-hemisphere glioma surgery?
How well can simple clinical features predict long-term language recovery after left-hemisphere glioma surgery?
Long-term language recovery after left-hemisphere glioma surgery varies substantially across patients. We investigated how...
The 4S of spinal astrocytoma: specific location, syrinx, spasticity and score on Modified Mccormick Scale (MMS) predict long term outcomes in patients undergoing surgical resection of intramedullary spinal astrocytomas
The 4S of spinal astrocytoma: specific location, syrinx, spasticity and score on Modified Mccormick Scale (MMS) predict long term outcomes in patients undergoing surgical resection of intramedullary spinal astrocytomas
The aim of this study was to explore the factors that could predict long term clinical outcomes in SA. A retrospective stu...
Clinical trial design for novel targeted agents in neuro-oncology
Clinical trial design for novel targeted agents in neuro-oncology
Biomarker-based clinical trials investigating targeted treatments for brain tumors have surged due to better access to bio...
Association of preoperative seizures with reduced expression of soluble CD163, an M2 macrophage marker, in the cerebrospinal fluid in isocitrate dehydrogenase wild-type glioblastoma
Association of preoperative seizures with reduced expression of soluble CD163, an M2 macrophage marker, in the cerebrospinal fluid in isocitrate dehydrogenase wild-type glioblastoma
To investigate the relationship between the tumor microenvironment (TME), tumor-related seizures (TRS), and cerebrospinal ...
Impact of upfront adjuvant chemoradiation on survival in patients with molecularly defined oligodendroglioma: the benefits of PCV over TMZ
Impact of upfront adjuvant chemoradiation on survival in patients with molecularly defined oligodendroglioma: the benefits of PCV over TMZ
Oligodendroglioma is an adult-type diffuse glioma defined by 1p/19q codeletion and IDH1/2 mutation. Treatment includes sur...
In-patient neurosurgical tumor treatments for malignant glioma patients in Germany
In-patient neurosurgical tumor treatments for malignant glioma patients in Germany
Treatment for malignant gliomas involves multiple disciplines, including neurosurgery, radiation therapy, medical and neur...
Advanced imaging reveals enhanced malignancy in glioblastomas involving the subventricular zone: evidence of increased infiltrative growth and perfusion
Advanced imaging reveals enhanced malignancy in glioblastomas involving the subventricular zone: evidence of increased infiltrative growth and perfusion
Glioblastoma’s infiltrative growth and heterogeneity are influenced by neural, molecular, genetic, and immunological...
Development and application of explainable artificial intelligence using machine learning classification for long-term facial nerve function after vestibular schwannoma surgery
Development and application of explainable artificial intelligence using machine learning classification for long-term facial nerve function after vestibular schwannoma surgery
Vestibular schwannomas (VSs) represent the most common cerebellopontine angle tumors, posing a challenge in preserving fac...
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2–3 gliomas
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2–3 gliomas
Radiation therapy (RT) is an integral treatment component in patients with glioma but associated with neurotoxicity. Proto...
Congress of Neurological Surgeons systematic review and evidence‑based guidelines on the management of recurrent diffuse low-grade glioma: update
Congress of Neurological Surgeons systematic review and evidence‑based guidelines on the management of recurrent diffuse low-grade glioma: update
Target population These recommendations apply to adult patients with recurrent WHO grade 2 infiltrative diffuse glioma (ol...
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