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Transcriptomic and microenvironment characteristics of triple-negative breast cancer under three different neoadjuvant treatment regimens
Transcriptomic and microenvironment characteristics of triple-negative breast cancer under three different neoadjuvant treatment regimens
Adding immunotherapy to chemotherapy can modestly improve the pathological complete response (pCR) rate in triple-negative...
Neoadjuvant response stratification based on complete, partial, and no response in HR-positive/HER2-positive breast cancer
Neoadjuvant response stratification based on complete, partial, and no response in HR-positive/HER2-positive breast cancer
This study aimed to evaluate the prognostic relevance of stratified pathological response -complete response (CR), partial...
Integrating large-scale in vitro functional genomic screen and multi-omics data to identify novel breast cancer targets
Integrating large-scale in vitro functional genomic screen and multi-omics data to identify novel breast cancer targets
Our goal is to leverage publicly available whole transcriptome and genome-wide CRISPR-Cas9 screen data to identify and pri...
Natural language processing for local, regional, and distant breast cancer relapse identification in pathology reports
Natural language processing for local, regional, and distant breast cancer relapse identification in pathology reports
Cancer registries rarely track breast cancer relapse due to the resource-intensive nature of manual chart review. To addre...
Clinicopathologic features and contralateral breast cancer risk in BRCA1/2 pathogenic variant carriers: a multicenter registry study of Japanese women
Clinicopathologic features and contralateral breast cancer risk in BRCA1/2 pathogenic variant carriers: a multicenter registry study of Japanese women
This large-scale study presents the clinicopathological characteristics and cumulative incidence of contralateral breast c...
Prescription and self-reported use of endocrine therapy among Black hormone receptor-positive breast cancer survivors in the Detroit Research on Cancer Survivors cohort
Prescription and self-reported use of endocrine therapy among Black hormone receptor-positive breast cancer survivors in the Detroit Research on Cancer Survivors cohort
Black women with hormone receptor-positive (HR +) breast cancer are twice as likely as White women to have weakly HR + tum...
Effects of intermittent discontinuation cyclin–dependent kinase inhibitors on metastatic breast cancer during Lebanon’s economic crisis
Effects of intermittent discontinuation cyclin–dependent kinase inhibitors on metastatic breast cancer during Lebanon’s economic crisis
This study examines the intermittent discontinuation of palbociclib based on its availability and its clinical outcomes du...
Evaluating clinical response to primary endocrine therapy in elderly breast cancer patients in routine practice
Evaluating clinical response to primary endocrine therapy in elderly breast cancer patients in routine practice
Endocrine therapy (ET) can be used as a definitive treatment in frail and elderly breast cancer patients who are unwilling...
Breast surgical site infections in patients undergoing lumpectomy with and without closure of defect
Breast surgical site infections in patients undergoing lumpectomy with and without closure of defect
Postoperative infection rates in the United States following breast cancer surgery, including mastectomy with or without r...
Survival impact of adjuvant capecitabine in triple-negative breast cancer Latin American patients with residual disease: a real-world study
Survival impact of adjuvant capecitabine in triple-negative breast cancer Latin American patients with residual disease: a real-world study
Patients with triple-negative breast cancer (TNBC) who do not achieve pathological complete response (non-pCR) after neoad...
Pathological complete response and survival outcomes in single hormone receptor-positive/HER2-negative breast cancer after neoadjuvant chemotherapy and its intrinsic biological features and immune landscape
Pathological complete response and survival outcomes in single hormone receptor-positive/HER2-negative breast cancer after neoadjuvant chemotherapy and its intrinsic biological features and immune landscape
Previous studies often combined double hormone receptor-positive (dHR +) and single HR-positive (sHR +) tumors...
Time trends, uptake, and oncological effects of risk-reducing surgeries in 3067 Danish carriers: a population-based study with matched controls
Time trends, uptake, and oncological effects of risk-reducing surgeries in 3067 Danish carriers: a population-based study with matched controls
Knowledge of the uptake and breast and ovarian cancer-preventive and survival effects of bilateral risk-reducing mastectom...
IHC4 and COMBINE scores for enhanced prognostic stratification in HR+/HER2− breast cancer patients after neoadjuvant chemotherapy
IHC4 and COMBINE scores for enhanced prognostic stratification in HR+/HER2− breast cancer patients after neoadjuvant chemotherapy
The prognostic value of pathological complete response (pCR) in HR+/HER2− breast cancer patients following neoadjuva...
Prolonged time to breast cancer surgery and the risk of metastasis: an explorative simulation analysis using epidemiological data from Germany and the USA
Prolonged time to breast cancer surgery and the risk of metastasis: an explorative simulation analysis using epidemiological data from Germany and the USA
Growing breast cancer is associated with an inherent risk of metastasis. If surgical treatment of breast cancer is delayed...
Malignant upgrade in lesions of uncertain malignant potential in the breast (B3 lesions) – is open excision always necessary?
Malignant upgrade in lesions of uncertain malignant potential in the breast (B3 lesions) – is open excision always necessary?
Unclear or suspicious breast findings are typically clarified by interventional breast biopsy. Lesions with uncertain mali...
Cognitive behavioral stress management effects on cancer-related distress and neuroendocrine signaling in breast cancer: differential effects by neighborhood disadvantage
Cognitive behavioral stress management effects on cancer-related distress and neuroendocrine signaling in breast cancer: differential effects by neighborhood disadvantage
Women residing in disadvantaged neighborhoods experience disparities in breast cancer (BC) survival which persist when acc...
Radar reflectors for marking of target lymph nodes in initially node-positive patients receiving neoadjuvant chemotherapy for breast cancer—a subgroup analysis of the prospective AXSANA (EUBREAST-03) trial
Radar reflectors for marking of target lymph nodes in initially node-positive patients receiving neoadjuvant chemotherapy for breast cancer—a subgroup analysis of the prospective AXSANA (EUBREAST-03) trial
Surgical staging procedures of the axilla in initially clinically node-positive (cN +) breast cancer patients receiv...
Treatment patterns and clinical outcomes in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative metastatic breast cancer treated with chemotherapy: a large-scale data analysis using the Japanese claims database
Treatment patterns and clinical outcomes in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative metastatic breast cancer treated with chemotherapy: a large-scale data analysis using the Japanese claims database
This study aimed to evaluate treatment patterns and clinical outcomes in patients with hormone receptor-positive (HR+)/hum...
Preferences of patients with high-risk HR + /HER2- breast cancer for adjuvant endocrine treatment: an adaptive choice-based conjoint analysis study from Germany
Preferences of patients with high-risk HR + /HER2- breast cancer for adjuvant endocrine treatment: an adaptive choice-based conjoint analysis study from Germany
This study aimed to identify preferences of patients with high-risk hormone receptor positive/human epidermal growth facto...
The regulation mechanism of perceived stress on cognitive function of patients with breast cancer undergoing chemotherapy: a multiple mediation analysis
The regulation mechanism of perceived stress on cognitive function of patients with breast cancer undergoing chemotherapy: a multiple mediation analysis
Cancer-related cognitive impairment (CRCI) is one of the severe side effects affecting the quality of life of breast cance...
Genetic counseling referral rates and genetic testing outcomes in women with young breast cancer: a 20-year Canadian review
Genetic counseling referral rates and genetic testing outcomes in women with young breast cancer: a 20-year Canadian review
Despite guidelines recommending genetic testing for all cases of very young breast cancer (VYBC), poor uptake has been rep...
Long-term outcomes of volume de-escalation for breast nodal irradiation
Long-term outcomes of volume de-escalation for breast nodal irradiation
NCCN recommendations suggest irradiating chest wall/breast only + regional node irradiation (RNI) of the undis...
Considerations for hereditary breast and ovarian cancer syndrome molecular diagnosis: experience from the clinical practice
Considerations for hereditary breast and ovarian cancer syndrome molecular diagnosis: experience from the clinical practice
The implementation of the next-generation sequencing (NGS) in clinical practice has improved the genetic diagnosis of Here...
Somatostatin receptor-targeted theranostics in patients with estrogen receptor-positive metastatic breast cancer—a prospective exploratory study
Somatostatin receptor-targeted theranostics in patients with estrogen receptor-positive metastatic breast cancer—a prospective exploratory study
Somatostatin receptor (SSTR) expression has been reported in estrogen receptor-positive (ER +) metastatic breast can...
High risk surveillance MRI may not be necessary in BRCA1/2 mutation carriers over 70 years old
High risk surveillance MRI may not be necessary in BRCA1/2 mutation carriers over 70 years old
The risk of developing breast cancer up to age 80 for women with BRCA1/2 mutations is approximately 69–72%. The risk...
The impact of coadministration of venlafaxine, citalopram or gabapentin on the metabolic activation of tamoxifen
The impact of coadministration of venlafaxine, citalopram or gabapentin on the metabolic activation of tamoxifen
Tamoxifen undergoes metabolic activation by cytochrome P450 (CYP) enzymes to metabolites with more potent anti-estrogenic ...
Mammographic density as a predictor of invasive breast cancer and ductal carcinoma in situ in over six million South Korean women
Mammographic density as a predictor of invasive breast cancer and ductal carcinoma in situ in over six million South Korean women
Evidence on the associations between categorical mammographic density and breast cancer risk by tumor invasiveness remains...
Use of adjuvant capecitabine in older patients with early-stage triple-negative breast cancer
Use of adjuvant capecitabine in older patients with early-stage triple-negative breast cancer
Patients with triple-negative breast cancer (TNBC) who have residual disease after neoadjuvant chemotherapy (NACT) benefit...
The natural history of ductal carcinoma in situ: development, validation, and estimated outcomes of the SimDCIS model
The natural history of ductal carcinoma in situ: development, validation, and estimated outcomes of the SimDCIS model
To develop a novel simulation model for ductal carcinoma in situ (DCIS), fully validate it, and provide new estimates for ...
Second primary non-breast cancers in young breast cancer survivors
Second primary non-breast cancers in young breast cancer survivors
We evaluated the incidence, timing, and risk factors for second primary non-breast cancers (SPNBC) among young breast canc...
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