Zhu J, Zhang K, Zhou Y, Wang R, Gong L, Wang C et al (2023) A carrier-free nanomedicine enables apoptosis-ferroptosis synergistic breast cancer therapy by targeting subcellular organelles. ACS Appl Mater Interfac. https://doi.org/10.1021/acsami.3c01350

Article  Google Scholar 

Zhao P, Song H, Gao F, Chen L, Qiu J, Jin J et al (2023) A novel derivative of curcumol, HCL-23, inhibits the malignant phenotype of triple-negative breast cancer and induces apoptosis and HO-1-dependent ferroptosis. Molecules. https://doi.org/10.3390/molecules28083389

Article  PubMed  PubMed Central  Google Scholar 

Zhang H, Zhu S, Zhou H, Li R, Xia X, Xiong H (2023) Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer. Front Oncol 13:1098357. https://doi.org/10.3389/fonc.2023.1098357

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yuan L, Liu J, Bao L, Qu H, Xiang J, Sun P (2023) Upregulation of the ferroptosis-related STEAP3 gene is a specific predictor of poor triple-negative breast cancer patient outcomes. Front Oncol 13:1032364. https://doi.org/10.3389/fonc.2023.1032364

Article  PubMed  PubMed Central  CAS  Google Scholar 

Xu N, Li B, Liu Y, Yang C, Tang S, Cho WC et al (2022) Ferroptosis and triple-negative breast cancer: potential therapeutic targets. Front Oncol 12:1017041. https://doi.org/10.3389/fonc.2022.1017041

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bou Zerdan M, Ghorayeb T, Saliba F, Allam S, Bou Zerdan M, Yaghi M et al (2022) Triple negative breast cancer: updates on classification and treatment in 2021. Cancers (Basel). https://doi.org/10.3390/cancers14051253

Article  PubMed  Google Scholar 

Li Y, Zhang H, Merkher Y, Chen L, Liu N, Leonov S et al (2022) Recent advances in therapeutic strategies for triple-negative breast cancer. J Hematol Oncol 15(1):121. https://doi.org/10.1186/s13045-022-01341-0

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zhao Y, Ruan X, Cheng J, Xu X, Gu M, Mueck AO (2023) PGRMC1 promotes triple-negative breast cancer cell growth via suppressing ferroptosis. Climacteric 26(2):135–142. https://doi.org/10.1080/13697137.2023.2170225

Article  PubMed  CAS  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209–249. https://doi.org/10.3322/caac.21660

Article  PubMed  CAS  Google Scholar 

Yang F, Xiao Y, Ding JH, Jin X, Ma D, Li DQ et al (2023) Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy. Cell Metab 35(1):84-100.e8. https://doi.org/10.1016/j.cmet.2022.09.021

Article  PubMed  CAS  Google Scholar 

Tong X, Yu Z, Xing J, Liu H, Zhou S, Huang Y et al (2023) LncRNA HCP5-encoded protein regulates ferroptosis to promote the progression of triple-negative breast cancer. Cancers (Basel). https://doi.org/10.3390/cancers15061880

Article  PubMed  Google Scholar 

Mbah NE, Lyssiotis CA (2022) Metabolic regulation of ferroptosis in the tumor microenvironment. J Biol Chem 298(3):101617. https://doi.org/10.1016/j.jbc.2022.101617

Article  PubMed  PubMed Central  CAS  Google Scholar 

Han C, Liu Y, Dai R, Ismail N, Su W, Li B (2020) Ferroptosis and its potential role in human diseases. Front Pharmacol 11:239

Article  PubMed  PubMed Central  CAS  Google Scholar 

Devos D, Moreau C, Devedjian JC, Kluza J, Petrault M, Laloux C et al (2014) Targeting chelatable iron as a therapeutic modality in Parkinson’s disease. Antioxid Redox Signal 21(2):195–210

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ye L, Jin F, Kumar SK, Dai Y (2021) The mechanisms and therapeutic targets of ferroptosis in cancer. Expert Opin Ther Targets 25(11):965–986

Article  PubMed  CAS  Google Scholar 

Liu M, Liu B, Liu Q, Du K, Wang Z, He N (2019) Nanomaterial-induced ferroptosis for cancer specific therapy. Coord Chem Rev 382:160–180

Article  CAS  Google Scholar 

Zhu L, Luo S, Zhu Y, Tang S, Li C, Jin X et al (2023) The emerging role of ferroptosis in various chronic liver diseases: opportunity or challenge. J Inflamm Res 16:381–389. https://doi.org/10.2147/jir.S385977

Article  PubMed  PubMed Central  Google Scholar 

Lin Z, Liu J, Kang R, Yang M, Tang D (2021) Lipid metabolism in ferroptosis. Adv Biol 5(8):2100396

Article  CAS  Google Scholar 

Luo L, Wang H, Tian W, Zeng J, Huang Y, Luo H (2021) Targeting ferroptosis for cancer therapy: iron metabolism and anticancer immunity. Am J Cancer Res 11(11):5508

PubMed  PubMed Central  CAS  Google Scholar 

Hassannia B, Vandenabeele P, Berghe TV (2019) Targeting ferroptosis to iron out cancer. Cancer Cell 35(6):830–849

Article  PubMed  CAS  Google Scholar 

Nedeljković M, Damjanović A (2019) Mechanisms of chemotherapy resistance in triple-negative breast cancer-how we can rise to the challenge. Cells. https://doi.org/10.3390/cells8090957

Article  PubMed  PubMed Central  Google Scholar 

Liu M, Kong XY, Yao Y, Wang XA, Yang W, Wu H et al (2022) The critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review. Ann Transl Med 10(6):368. https://doi.org/10.21037/atm-21-6942

Article  PubMed  PubMed Central  CAS  Google Scholar 

Li FJ, Long HZ, Zhou ZW, Luo HY, Xu SG, Gao LC (2022) System X(c) (-)/GSH/GPX4 axis: an important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy. Front Pharmacol 13:910292. https://doi.org/10.3389/fphar.2022.910292

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wang B, Wang Y, Zhang J, Hu C, Jiang J, Li Y et al (2023) ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis. Arch Toxicol 97(6):1439–1451. https://doi.org/10.1007/s00204-023-03476-6

Article  PubMed  CAS  Google Scholar 

Xu L, Liu Y, Chen X, Zhong H, Wang Y (2023) Ferroptosis in life: to be or not to be. Biomed Pharmacother 159:114241. https://doi.org/10.1016/j.biopha.2023.114241

Article  PubMed  CAS  Google Scholar 

Rohr-Udilova N, Bauer E, Timelthaler G, Eferl R, Stolze K, Pinter M et al (2018) Impact of glutathione peroxidase 4 on cell proliferation, angiogenesis and cytokine production in hepatocellular carcinoma. Oncotarget 9(11):10054–10068. https://doi.org/10.18632/oncotarget.24300

Article  PubMed  PubMed Central  Google Scholar 

Sugezawa K, Morimoto M, Yamamoto M, Matsumi Y, Nakayama Y, Hara K et al (2022) GPX4 regulates tumor cell proliferation via suppressing ferroptosis and exhibits prognostic significance in gastric cancer. Anticancer Res 42(12):5719–5729. https://doi.org/10.21873/anticanres.16079

Article  PubMed  CAS  Google Scholar 

Zhang X, Sui S, Wang L, Li H, Zhang L, Xu S et al (2020) Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin. J Cell Physiol 235(4):3425–3437. https://doi.org/10.1002/jcp.29232

Article